Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor


  1. 2019
  2. E-pub ahead of print

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice. / Jepsen, Sara L.; Grunddal, Kaare V.; Wewer Albrechtsen, Nicolai J; Engelstoft, Maja S; Gabe, Maria B N; Jensen, Elisa P; Ørskov, Cathrine; Poulsen, Steen S; Rosenkilde, Mette M; Pedersen, Jens; Gribble, Fiona M; Reimann, Frank; Deacon, Carolyn F; Schwartz, Thue W; Christ, Andreas D; Martin, Rainer E; Holst, Jens J.

    In: A J P: Endocrinology and Metabolism (Online), 10.09.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure : A Pilot Study. / Clarke, Sophie J.; Pettit, Stephen; Giblett, Joel P.; Zhao, Tian; Kydd, Anna C.; Albrechtsen, Nicolai J. W.; Deacon, Carolyn F.; Parameshwar, Jayan; Hoole, Stephen P.

    In: Clinical Therapeutics, Vol. 41, No. 1, 2019, p. 118-127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes. / Deacon, Carolyn F.

    In: Frontiers in Endocrinology, Vol. 10, 80, 2019.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men. / Wewer Albrechtsen, Nicolai J; Mark, Peter D; Terzic, Dijana; Hansen, Lasse H; Andersen, Ulrik Ø; Hartmann, Bolette; Carr, Richard D; Gustafsson, Finn; Deacon, Carolyn F; Holst, Jens J; Goetze, Jens P; Plomgaard, Peter.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 104, No. 9, 2019, p. 3868-3876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    GLP-1 Is a Coronary Artery Vasodilator in Humans. / Clarke, Sophie J.; Giblett, Joel P.; Yang, Lucy L.; Hubsch, Annette; Zhao, Tian; Aetesam-ur-Rahman, Muhammad; West, Nick E. J.; O'Sullivan, Michael; Figg, Nichola; Bennett, Martin; Albrechtsen, Nicolai J. Wewer; Deacon, Carolyn F.; Cheriyan, Joseph; Hoole, Stephen P.

    In: Journal of the American Heart Association, Vol. 7, No. 22, e010321, 20.11.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects. / Samkani, Amirsalar Agertoft; Skytte, Mads J; Thomsen, Mads N; Astrup, Arne; Deacon, Carolyn F; Holst, Jens Juul; Madsbad, Sten; Rehfeld, Jens Frederik; Krarup, Thure; Haugaard, Steen B.

    In: Nutrients, Vol. 10, No. 9, 1285, 09.2018, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes? / Andersen, Emilie S.; Lund, A.; Bagger, J. I.; Andreasen, C; Grøndahl, MF; Deacon, Carolyn F.; Hartmann, Bolette; Holst, Jens Juul; Knop, Filip Krag; Lauritsen, Tina Vilsbøll.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 8, 08.2018, p. 1937-1943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Ghrelin secretion in humans - a role for the vagus nerve? / Veedfald, S; Plamboeck, A; Hartmann, B; Vilsbøll, T; Knop, F K; Deacon, C F; Svendsen, L B; Holst, J J.

    In: Neurogastroenterology and Motility, Vol. 30, No. 6, e13295, 06.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A review of dipeptidyl peptidase-4 inhibitors : Hot topics from randomized controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, 02.2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Peptide degradation and the role of DPP-4 inhibitors in the treatment of type 2 diabetes. / Deacon, Carolyn F.

    In: Peptides, Vol. 100, 02.2018, p. 150-157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients. / Samkani, Amirsalar; Skytte, Mads Gustav Juul; Kandel, Daniel; Kjaer, Stine; Astrup, Arne; Deacon, Carolyn F.; Holst, Jens J; Madsbad, Sten; Rehfeld, Jens Frederik; Haugaard, Steen Bendix; Krarup, Thure.

    In: British Journal of Nutrition, Vol. 119, No. 8, 2018, p. 910-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. Suppl. 1, 2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice. / Christiansen, Charlotte B.; Lind, Sara J.; Svendsen, Berit; Balk-Møller, Emilie; Dahlby, Tina; Kuhre, Rune E; Hartmann, Bolette; Mandrup-Poulsen, Thomas; Deacon, Carolyn F; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: Physiological Reports, Vol. 6, No. 13, e13788, 2018, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas. / Kuhre, Rune Ehrenreich; Albrechtsen, Nicolai Jacob Wewer; Larsen, Olav; Jepsen, Sara Lind; Balk-Møller, Emilie; Andersen, Daniel Bjørklund; Deacon, Carolyn F.; Schoonjans, Kristina; Reimann, Frank ; Gribble, Fiona M.; Albrechtsen, Reidar; Hartmann, Bolette; Rosenkilde, Mette; Holst, Jens Juul.

    In: Molecular Metabolism, Vol. 11, 2018, p. 84-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors? / Andersen, Emilie S.; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 1, 2018, p. 34-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men. / Veedfald, Simon; Wu, Tongzhi; Bound, Michelle; Grivell, Jacqueline; Hartmann, Bolette; Rehfeld, Jens F.; Deacon, Carolyn F.; Horowitz, Michael; Holst, Jens J.; Rayner, Christopher K.

    In: Journal of Clinical Endocrinology & Metabolism, Vol. 103, No. 12, 2018, p. 4409-4418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides : a randomized trial. / Samkani, Amirsalar; Skytte, Mads Gustav Juul; Anholm, Christian; Astrup, Arne; Deacon, Carolyn F; Holst, Jens Juul; Madsbad, Sten; Boston, Ray; Krarup, Thure; Haugaard, Steen B.

    In: Lipids in Health and Disease, Vol. 17, 295, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2017
  21. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues. / Ten Kulve, Jennifer S; Veltman, Dick J; Gerdes, Victor E A; van Bloemendaal, Liselotte; Barkhof, Frederik; Deacon, Carolyn F; Holst, Jens J; Drent, Madeleine L; Diamant, Michaela; IJzerman, Richard G.

    In: Diabetes Care, Vol. 40, No. 11, 11.2017, p. 1522-1529.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse? / Windeløv, Johanne A; Wewer Albrechtsen, Nicolai J; Kuhre, Rune E; Jepsen, Sara L; Hornburg, Daniel; Pedersen, Jens; Jensen, Elisa P; Galsgaard, Katrine D; Winther-Sørensen, Marie; Ørgaard, Anne; Deacon, Carolyn F; Mann, Matthias; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens J.

    In: Diabetologia, Vol. 60, No. 10, 10.2017, p. 2066-2075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite. / Wewer Albrechtsen, Nicolai J; Asmar, Ali; Jensen, Frederik; Törang, Signe; Simonsen, Lene; Kuhre, Rune E; Asmar, Meena; Veedfald, Simon; Plamboeck, Astrid; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Nauck, Michael A; Deacon, Carolyn F; Bülow, Jens; Holst, Jens J; Hartmann, Bolette.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 313, No. 3, 01.09.2017, p. E284-E291.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men. / Matikainen, N; Söderlund, S; Björnson, E; Bogl, L H; Pietiläinen, K H; Hakkarainen, A; Lundbom, N; Eliasson, B; Räsänen, S M; Rivellese, A; Patti, L; Prinster, A; Riccardi, G; Després, J-P; Alméras, N; Holst, J J; Deacon, C F; Borén, J; Taskinen, M-R.

    In: Nutrition, Metabolism & Cardiovascular Diseases, Vol. 27, No. 6, 06.2017, p. 534-542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia. / Craig, Colleen M; Liu, Li-Fen; Deacon, Carolyn F; Holst, Jens J; McLaughlin, Tracey L.

    In: Diabetologia, Vol. 60, No. 3, 03.2017, p. 531-540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide : A randomized controlled trial in patients with type 2 diabetes. / Nauck, Michael A; Kahle, Melanie; Baranov, Oleg; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 2, 06.02.2017, p. 200-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.

    In: European Journal of Nutrition, Vol. 56, No. 3, 2017, p. 1063-1076.

    Research output: Contribution to journalJournal articleResearchpeer-review

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