Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor


  1. Published

    A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes

    Wu, T., Little, T., Bound, M., Borg, M., Zhang, X., Deacon, Carolyn F., Horowitz, M., Jones, K. & Rayner, C., 2016, In : Diabetes Care. 39, 4, p. 511-517 7 p.

    Research output: Contribution to journalJournal article

  2. Published

    A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients

    Samkani, A., Skytte, M. G. J., Kandel, D., Kjaer, S., Astrup, Arne, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In : British Journal of Nutrition. 119, 8, p. 910-917 8 p.

    Research output: Contribution to journalJournal article

  3. Published

    A comparative review of DPP-4 inhibitors and sulphonylureas

    Deacon, Carolyn F. & Lebovitz, H., 2016, In : Diabetes, Obesity and Metabolism. 18, p. 333-347

    Research output: Contribution to journalJournal article

  4. Published

    A review of dipeptidyl peptidase-4 inhibitors: Hot topics from randomized controlled trials

    Deacon, Carolyn F., Feb 2018, In : Diabetes, Obesity and Metabolism. 20, p. 34-46 13 p.

    Research output: Contribution to journalReview

  5. Published

    A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials

    Deacon, Carolyn F., 2018, In : Diabetes, Obesity and Metabolism. 20, Suppl. 1, p. 34-46

    Research output: Contribution to journalReview

  6. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, Jens, Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In : American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journalJournal article

  7. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

    Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, Holstein-Rathlou, N., Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In : A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

    Research output: Contribution to journalJournal article

  8. Published

    Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects

    Samkani, A. A., Skytte, M. J., Thomsen, M. N., Astrup, Arne, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, Sep 2018, In : Nutrients. 10, 9, p. 1-14 14 p., 1285.

    Research output: Contribution to journalJournal article

  9. Published
  10. Published

    Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

    Olthof, M., van Dijk, A., Deacon, Carolyn F., Heine, R. & van Dam, R., 2011, In : Nutrition & Metabolism. 8, p. Artikel 10 4 p.

    Research output: Contribution to journalJournal article

  11. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes

    Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In : Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.

    Research output: Contribution to journalJournal article

  12. Published

    Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

    Deacon, Carolyn F., 2008, In : Current Opinion in Investigational Drugs. 9, 4, p. 402-13 11 p.

    Research output: Contribution to journalJournal article

  13. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future

    Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In : Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.

    Research output: Contribution to journalJournal article

  14. Published
  15. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In : Diabetes. 44, p. 1126-1131

    Research output: Contribution to journalJournal article

  16. Published
  17. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

    Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

    Research output: Contribution to journalJournal article

  18. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In : European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal article

  19. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Hornburg, D., Jensen, C. Z., Hornum, Mads, Dirksen, C., Svane, M., Gasbjerg, Lærke Smidt, Jorgensen, N. B., Gabe, Maria Buur Nordskov, Balk-Moller, E., Albrechtsen, Reidar, Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Meissner, F., Jorsal, T., Lund, A., Vilsbøll, Tina, Eliasen, R., Bojsen-Moller, K. N., Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In : Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal article

  20. Published

    Circulation and degradation of GIP and GLP-1

    Deacon, Carolyn F., 2004, In : Hormone and Metabolic Research. 36, p. 761-765

    Research output: Contribution to journalJournal article

  21. Published

    Commentary: Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes?

    Deacon, Carolyn F., 2012, In : Diabetes. 61, 9, p. 2219-2220

    Research output: Contribution to journalJournal article

  22. Published

    Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.

    Deacon, Carolyn F. & Lebovitz, H., 2016, In : Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.

    Research output: Contribution to journalReview

  23. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

    Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In : Diabetologia. 60, 3, p. 531-540

    Research output: Contribution to journalJournal article

  24. Published

    DPP-4 inhibition – advances in our understanding of diabetes management

    Deacon, Carolyn F. & Holst, Jens Juul, 2009, In : European Endocrinology. 4, p. 47-49

    Research output: Contribution to journalReview

  25. Published

    DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

    Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In : Frontiers in Bioscience. 13, p. 1780-94 14 p.

    Research output: Contribution to journalJournal article

  26. Published

    Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide

    Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581

    Research output: Contribution to journalJournal article

  27. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

    Research output: Contribution to journalJournal article

  28. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In : European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

    Research output: Contribution to journalJournal article

  29. Published

    Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men

    Lindgren, O., Mari, A., Deacon, Carolyn F., Carr, R. D., Winzell, M. S., Vikman, J. & Ahrén, B., 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2887-92 5 p.

    Research output: Contribution to journalJournal article

  30. Published

    Differential regional metabolism of glucagon in anesthetized pigs.

    Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In : American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60

    Research output: Contribution to journalJournal article

  31. Published

    Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes.

    Deacon, Carolyn F., 2007, In : Expert Opinion on Investigational Drugs. 16, 4, p. 533-45 12 p.

    Research output: Contribution to journalJournal article

  32. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.

    Deacon, Carolyn F. & Holst, Jens Juul, 2002, In : Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.

    Research output: Contribution to journalJournal article

  33. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In : Diabetes. 47, p. 764-769

    Research output: Contribution to journalJournal article

  34. Published

    Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs

    Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In : Diabetes. 50, p. 1588-1597

    Research output: Contribution to journalJournal article

  35. Published

    Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.

    Deacon, Carolyn F. & Holst, Jens Juul, 2005, In : International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.

    Research output: Contribution to journalJournal article

  36. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In : Diabetologia. 41, p. 271-278

    Research output: Contribution to journalJournal article

  37. Published
  38. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

    Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, Jens Juul, Deacon, Carolyn F., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D., Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In : Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

    Research output: Contribution to journalJournal article

  39. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

    Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In : Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.

    Research output: Contribution to journalJournal article

  40. Published

    Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review

    Deacon, Carolyn F., Jan 2011, In : Diabetes, Obesity and Metabolism. 13, 1, p. 7-18 12 p.

    Research output: Contribution to journalReview

  41. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects

    Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In : Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.

    Research output: Contribution to journalJournal article

  42. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors?

    Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In : Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.

    Research output: Contribution to journalJournal article

  43. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In : American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

    Research output: Contribution to journalJournal article

  44. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

    Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In : Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

    Research output: Contribution to journalJournal article

  45. Published

    Effect of Sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes

    Tremblay, A., Lamarche, B., Deacon, Carolyn F., Weisnagel, S. & Couture, P., Apr 2011, In : Diabetes, Obesity and Metabolism. 13, 4, p. 366-373 8 p.

    Research output: Contribution to journalJournal article

  46. Published

    Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In : Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.

    Research output: Contribution to journalJournal article

  47. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

    Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q., Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

    Research output: Contribution to journalJournal article

  48. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In : Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

    Research output: Contribution to journalJournal article

  49. Published

    Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study

    Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Parameshwar, J. & Hoole, S. P., 2019, In : Clinical Therapeutics. 41, 1, p. 118-127 10 p.

    Research output: Contribution to journalJournal article

  50. Published

    Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes

    Tharp, W. G., Gupta, D., Sideleva, O., Deacon, Carolyn F., Holst, Jens Juul, Elahi, D. & Pratley, R. E., 2020, In : Diabetes. 69, 2, p. 146-157

    Research output: Contribution to journalJournal article

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