Bolette Hartmann

Bolette Hartmann

Associate Professor


  1. 1994
  2. Published

    Proglucagon processing in porcine and human pancreas

    Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In : Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1999
  4. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In : Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2000
  6. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In : Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, Peter Bak, Sep 2000, In : Gut. 47, 3, p. 370-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

    Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, M. H., 1 May 2000, In : Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In : Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2001
  11. Published

    Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, Flemming, Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul & Mortensen, Peter Bak, Mar 2001, In : Gastroenterology. 120, 4, p. 806-815 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In : Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2002
  14. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon

    Haderslev, K. V., Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In : Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2003
  16. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1

    Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In : Gastroenterology. 125, 1, p. 136-47 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In : Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Injected TFF1 and TFF3 bind to TFF2-immunoreactive cells in the gastrointestinal tract in rats

    Poulsen, Steen Seier, Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Nexø, E. & Thim, L., 2003, In : Regulatory Peptides. 115, 2, p. 91-99 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In : Regulatory Peptides. 116, 1-3, p. 21-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, Lone Brinkmann, Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, Arne, Apr 2003, In : International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2004
  22. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In : Regulatory Peptides. 118, 1-2, p. 11-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In : Journal of Nutrition. 134, 6, p. 1467-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In : Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In : Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2005
  27. Published

    Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment

    Andreassen, B. U., Paerregaard, A., Schmiegelow, Kjeld, Rechnitzer, C., Heilman, C., Hartmann, Bolette, Holst, Jens Juul & Michaelsen, Kim F., Jan 2005, In : Journal of Pediatric Gastroenterology and Nutrition. 40, 1, p. 48-53 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome

    Martin, G. R., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Demchyshyn, L., Toney, K. & Sigalet, D. L., Mar 2005, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 288, 3, p. G431-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY

    Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In : European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2007
  31. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In : Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In : Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In : Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2008
  35. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In : Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In : Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2009
  38. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In : Bone. 45, 5, p. 833-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In : Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2010
  41. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In : Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2011
  43. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., nsx114, nsx114, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In : Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Reduction of parathyoid hormone levels

    Hartmann, Bolette & B. Henriksen, D., 1 Apr 2011, Patent No. US2010/0081,622, 28 Sep 2009

    Research output: Patent

  45. Published

    Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning

    Thymann, Thomas, Huërou-Luron, I. L., Petersen, Y. M., Hedemann, M. S., Elnif, J., Jensen, B. B., Hartmann, Bolette, Holst, Jens Juul & Sangild, Per Torp, 2011, 44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), p. 202 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  46. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, Signe Sørensen, Ma, L., Grarup, Niels, Hartmann, Bolette, Hainerová, I. A., Kielgast, U., Kissow, Hannelouise, Rosenkilde, Mette, Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, Allan René, Madsbad, Sten, Holst, Jens Juul, Hansen, Torben, Pedersen, Oluf Borbye & GIANT Consortium, G. C., 2011, In : Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2012
  48. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model

    Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In : Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine

    Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In : Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In : Regulatory Peptides. 179, 1-3, p. 91-100 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul & Poulsen, Steen Seier, 20 Oct 2012, In : Gut.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome

    Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In : European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs

    Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In : Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2013
  55. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure

    Askov-Hansen, C., Jeppesen, Palle Bekker, Lund, P., Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 10 Feb 2013, In : Regulatory Peptides. 181, p. 4-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass

    Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In : International Journal of Obesity. 37, p. 1452-1459 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin

    Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, J., 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  58. Published

    Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males

    Lund, M. T., Taudorf, L., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 1 Nov 2013, In : European Journal of Applied Physiology. 113, 11, p. 2737-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study

    Madsen, K. B., Askov-Hansen, C., Naimi, R. M., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, Peter Bak & Jeppesen, Palle Bekker, 10 Jun 2013, In : Regulatory Peptides. 184, 10, p. 30-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients

    Naimi, R. M., Madsen, K. B., Askov-Hansen, C., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In : Regulatory Peptides. 184, 10, p. 47-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In : European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients

    Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In : Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates

    Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, Stine Brandt, Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2014
  66. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In : Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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