Bo Hjorth Bentzen
Associate Professor
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3
2200 København N.
- Published
2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels
Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.Research output: Contribution to journal › Journal article › Research › peer-review
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4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries
Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels
Simo Vicens, R., Kirchhoff, J. E., Dolce , B., Abildgaard, L., Speerschneider, T., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 5 Dec 2017, In: British Journal of Pharmacology. 174, 23, p. 4396-4408 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Loss-of-Function Variant in the Chloride Ion Channel Gene Clcn2 Associates with Atrial Fibrillation
Hansen, T. H., Yan, Y., Ahlberg, G., Vad, O. B., Refsgaard, L., Dos Santos, J. L., Mutsaers, N., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, 29 Jan 2020, In: Scientific Reports. 10, 1, 10 p., 1453.Research output: Contribution to journal › Journal article › Research › peer-review
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A comparison of two models of experimental periodontitis in rats
Bentzen, Bo Hjorth, Grauballe, M. C. B., Björnsson, M. J., Stoltze, K., Hjørting-Hansen, E. & Holmstrup, Palle, 2005, In: Scandinavian Journal of Laboratory Animal Science. 2, p. 73-80Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation
Yfanti, C., Vestbjerg, B., van't Westende, J., Edvardsson, N., Monfort, L. M., Olesen, Morten Steen Salling, Bentzen, Bo Hjorth, Grunnet, Morten, Eveleens Maarse, B. C., Diness, Jonas Goldin, Kemme, M. J. B., Sørensen, U., Moerland, M., van Esdonk, M. J., Klaassen, E. S., Gal, P. & Holst, A. G., 2024, (E-pub ahead of print) In: British Journal of Clinical Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury
Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro
Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Tzortzini, E., Xue, K., Giller, K., Becker, S., Mujezinovic, A., Bentzen, Bo Hjorth, Andreas, L. B., Kolocouris, A., Kledal, T. N. & Rosenkilde, Mette, 2021, In: Communications Biology. 4, 10 p., 1347.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats
Bentzen, Bo Hjorth, Grunnet, Morten, Hyveled-Nielsen, L., Sundgreen, C., lassen, J. B. & Hansen, H. H., 2012, In: Obesity.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium
Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization
Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure
Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BK channel activators and their therapeutic perspectives
Bentzen, Bo Hjorth, Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzimidazolyl-acetamide derivatives useful as potassium channel modulators
SØRENSEN, U. S., Grunnet, Morten, Bentzen, Bo Hjorth, Christophersen, P., Diness, Jonas Goldin, SKIBSBYE, L. & Strøbæk, D., 7 Jan 2013Research output: Other contribution › Research
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Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms
Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiac ion channels and mechanisms for protection against atrial fibrillation.
Grunnet, Morten, Bentzen, Bo Hjorth, Sørensen, U. S. & Diness, Jonas Goldin, 2011, In: Reviews of Physiology, Biochemistry and Pharmacology. 162, p. 1-58 59 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Central and Peripheral GABA(A) Receptor Regulation of the Heart Rate Depends on the Conscious State of the Animal
Bentzen, Bo Hjorth & Grunnet, Morten, 2011, In: Advances in Pharmacological Sciences. 2011, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart
Osadchii, O. E., Bentzen, Bo Hjorth & Olesen, Søren-Peter, 2009, In: Experimental Physiology. 94, 4, p. 434-46 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing
Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Gentilini, F., Forni, M., Zannoni, A., Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia
Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants
Gregers, E., Ahlberg, G., Christensen, T., Jabbari, J., Larsen, K. O., Herfelt, C. B., Henningsen, K. M., Andreasen, Laura Korsholm, Thiis, J. J., Lund, J., Holme, S., Haunsø, Stig, Bentzen, Bo Hjorth, Schmitt, Nicole, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, Oct 2017, In: Heart Rhythm. 14, 10, p. 1531-1538Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels
Larsen, A. P., Bentzen, Bo Hjorth & Grunnet, Morten, Oct 2010, In: British Journal of Pharmacology. 161, 3, p. 614-28 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels
Simo Vicens, R., Sauter, D. R. P., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 15 May 2017, In: European Journal of Pharmacology. 803, p. 118-123 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction
Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval
Hiniesto-Iñigo, I., Castro-Gonzalez, L. M., Corradi, V., Skarsfeldt, M. A., Yazdi, S., Lundholm, S., Nikesjö, J., Noskov, S. Y., Bentzen, Bo Hjorth, Tieleman, D. P. & Liin, S. I., 2023, In: EBioMedicine. 89, 17 p., 104459.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13529
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342
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Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
341
downloads
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
252
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Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer
Research output: Contribution to journal › Journal article › Research › peer-review
Published