Bo Hjorth Bentzen

Bo Hjorth Bentzen

Associate Professor

ORCID: 0000-0002-0253-4992

Publication year:
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1 - 50 out of 71Page size: 50
  1. 2003
  2. Published

    The effect of spironolactone on experimental periodontitis in rats

    Grauballe, M. C. B., Bentzen, Bo Hjorth, Bjørnson, M., Moe, D., Jonassen, K., Bendtzen, K. & Holmstrup, Palle, 2003.

    Research output: Contribution to conference › Conference abstract for conference › Research

  3. 2005
  4. Published

    A comparison of two models of experimental periodontitis in rats

    Bentzen, Bo Hjorth, Grauballe, M. C. B., Björnsson, M. J., Stoltze, K., Hjørting-Hansen, E. & Holmstrup, Palle, 2005, In: Scandinavian Journal of Laboratory Animal Science. 2, p. 73-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2006
  6. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2007
  8. Published

    Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

    Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, Morten, Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In: Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.

    Bentzen, Bo Hjorth, Nardi, A., Callø, Kirstine, Madsen, L. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Molecular Pharmacology. 72, 4, p. 1033-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2009
  11. Published

    Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

    Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart

    Osadchii, O. E., Bentzen, Bo Hjorth & Olesen, Søren-Peter, 2009, In: Experimental Physiology. 94, 4, p. 434-46 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Synthesis and characterisation of NS13558: a new important tool for addressing KCa1.1 channel function ex vivo

    Bentzen, Bo Hjorth, Andersen, R. W., Olesen, Søren-Peter, Grunnet, Morten & Nardi, A., 2009, In: NAUNYN-SCHMIEDEBERGS ARCHIV FUR EXPERIMENTELLE PATHOLOGIE UND PHARMAKOLOGIE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2010
  15. Published

    Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels

    Larsen, A. P., Bentzen, Bo Hjorth & Grunnet, Morten, Oct 2010, In: British Journal of Pharmacology. 161, 3, p. 614-28 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2011
  17. Published

    Cardiac ion channels and mechanisms for protection against atrial fibrillation.

    Grunnet, Morten, Bentzen, Bo Hjorth, Sørensen, U. S. & Diness, Jonas Goldin, 2011, In: Reviews of Physiology, Biochemistry and Pharmacology. 162, p. 1-58 59 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Central and Peripheral GABA(A) Receptor Regulation of the Heart Rate Depends on the Conscious State of the Animal

    Bentzen, Bo Hjorth & Grunnet, Morten, 2011, In: Advances in Pharmacological Sciences. 2011, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits

    Bentzen, Bo Hjorth, Bahrke, S., Wu, K., Larsen, A. P., Odening, K. E., Franke, G., Storm vans Gravesande, K., Biermann, J., Peng, X., Koren, G., Zehender, M., Bode, C., Grunnet, Morten & Brunner, M., Feb 2011, In: Journal of Cardiovascular Pharmacology. 57, 2, p. 223-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2012
  22. Published

    Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats

    Bentzen, Bo Hjorth, Grunnet, Morten, Hyveled-Nielsen, L., Sundgreen, C., lassen, J. B. & Hansen, H. H., 2012, In: Obesity.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

    Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

    Olesen, M. S., Bentzen, Bo Hjorth, Nielsen, J. B., Steffensen, Annette Buur, David, J., Jabbari, J., Jensen, H., Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, 2012, In: B M C Medical Genetics. 13, p. 24

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

    Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2013
  27. Published

    Benzimidazolyl-acetamide derivatives useful as potassium channel modulators

    SØRENSEN, U. S., Grunnet, Morten, Bentzen, Bo Hjorth, Christophersen, P., Diness, Jonas Goldin, SKIBSBYE, L. & Strøbæk, D., 7 Jan 2013

    Research output: Other contribution › Research

  28. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2014
  30. Published

    BK channel activators and their therapeutic perspectives

    Bentzen, Bo Hjorth, Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

    Soltysinska, E., Bentzen, B. H., Barthmes, M., Hattel, H., Thrush, A. B., Harper, M-E., Qvortrup, K., Larsen, F. J., Schiffer, T. A., Losa-Reyna, J., Straubinger, J., Kniess, A., Thomsen, M. B., Brüggemann, A., Fenske, S., Biel, M., Ruth, P., Wahl-Schott, C., Boushel, R. C., Olesen, S-P. & 1 others, Lukowski, R., 2014, In: PLOS ONE. 9, 7, p. 1-12 12 p., e103402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

    Nielsen, J. B., Bentzen, Bo Hjorth, Olesen, Morten Steen Salling, David, J., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, Apr 2014, In: Biomarkers in Medicine. 8, 4, p. 557-570 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370

    Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Stott, J. B., Povstyan, O. V., Sivaloganathan, K., Dalby-Brown, W. & Greenwood, I. A., 9 Jun 2014, In: British Journal of Pharmacology. 171, 19, p. 4413-4424 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

    Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

    Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2015
  37. Published

    Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel

    Liin, S. I., Silverå Ejneby, M., Barro-Soria, R., Skarsfeldt, M. A., Larsson, J. E., Starck Härlin, F., Parkkari, T., Bentzen, Bo Hjorth, Schmitt, Nicole, Larsson, H. P. & Elinder, F., 5 May 2015, In: Proceedings of the National Academy of Science of the United States of America. 112, 18, p. 5714–5719 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

    Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

    Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Role of calcium activated potassium channels in atrial fibrillation pathophysiology and therapy

    Diness, Jonas Goldin, Bentzen, Bo Hjorth, S. Sørensen, U. & Grunnet, Morten, Nov 2015, In: Journal of Cardiovascular Pharmacology. 66, 5, p. 441-448 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2016
  42. Published

    Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes

    Liin, S. I., Karlsson, U., Bentzen, Bo Hjorth, Schmitt, Nicole & Elinder, F., 23 Feb 2016, In: Acta Physiologica (Print). 218, 1, p. 28-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

    Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations

    Liin, S. I., Larsson, J. E., Barro-Soria, R., Bentzen, Bo Hjorth & Larsson, H. P., 30 Sep 2016, In: eLife. 5, 19 p., e20272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2017
  47. Published

    Novel negative allosteric modulator inhibits small conductance calcium-activated potassium channels and selectively prolongs atrial refractoriness in conscious pigs

    Simó-Vicens, R., Citerni, C., Edvardsson, N. G., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 11 May 2017, In: Heart Rhythm. 14, 5 suppl., p. S149-S150 P-PO02-15.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. Published

    Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels

    Simo Vicens, R., Sauter, D. R. P., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 15 May 2017, In: European Journal of Pharmacology. 803, p. 118-123 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants

    Gregers, E., Ahlberg, G., Christensen, T., Jabbari, J., Larsen, K. O., Herfelt, C. B., Henningsen, K. M., Andreasen, Laura Korsholm, Thiis, J. J., Lund, J., Holme, S., Haunsø, Stig, Bentzen, Bo Hjorth, Schmitt, Nicole, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, Oct 2017, In: Heart Rhythm. 14, 10, p. 1531-1538

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels

    Simo Vicens, R., Kirchhoff, J. E., Dolce , B., Abildgaard, L., Speerschneider, T., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 5 Dec 2017, In: British Journal of Pharmacology. 174, 23, p. 4396-4408 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2018
  53. Published

    Multiple genetic variations in sodium channel subunits in a case of sudden infant death syndrome

    Denti, F., Bentzen, Bo Hjorth, Wojciak, J., Thomsen, N. M., Scheinman, M. & Schmitt, Nicole, 2018, In: Pacing and Clinical Electrophysiology. 41, 6, p. 620-626

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

    Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, Christian, Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In: Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization

    Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Homozygosity for SCN4A Arg1142Gln causes congenital myopathy with variable disease expression

    Sloth, C. K., Denti, F., Schmitt, Nicole, Bentzen, Bo Hjorth, Fagerberg, C., Vissing, John & Gaist, D., Oct 2018, In: Neurology: Genetics. 4, 5, p. e267 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer

    Jensen, K., Skarsfeldt, M. A., Stærkind, Hans, Arnbak, J., Balabas, M. V., Olesen, Søren-Peter, Bentzen, Bo Hjorth & Polzik, Eugene Simon, 1 Nov 2018, In: Scientific Reports. 8, 9 p., 16218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels

    Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. 2019
  61. Published

    The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

    Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2020
  63. Published

    Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Gentilini, F., Forni, M., Zannoni, A., Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Functional phenotype variations of two novel Kv 7.1 mutations identified in patients with Long QT syndrome

    Bomholtz, Sofia Hammami, Refaat, M., Steffensen, Annette Buur, David, J., Espinosa, K., Nussbaum, R., Wojciak, J., Bentzen, Bo Hjorth, Scheinman, M. & Schmitt, Nicole, 2020, In: Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders

    Grupe, M., Bentzen, Bo Hjorth, Benned-Jensen, T., Nielsen, V., Frederiksen, K., Jensen, H. S., Jacobsen, A., Skibsbye, L., Sams, A. G., Grunnet, M., Rottlander, M. & Bastlund, J. F., 2020, In: European Journal of Pharmacology. 887, 12 p., 173440.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation

    Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.

    Research output: Contribution to journal › Journal article › Research › peer-review

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