Bo Hjorth Bentzen

Bo Hjorth Bentzen

Associate Professor


  1. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    BK channel activators and their therapeutic perspectives

    Bentzen, Bo Hjorth, Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits

    Bentzen, Bo Hjorth, Bahrke, S., Wu, K., Larsen, A. P., Odening, K. E., Franke, G., Storm vans Gravesande, K., Biermann, J., Peng, X., Koren, G., Zehender, M., Bode, C., Grunnet, Morten & Brunner, M., Feb 2011, In: Journal of Cardiovascular Pharmacology. 57, 2, p. 223-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

    Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats

    Bentzen, Bo Hjorth, Grunnet, Morten, Hyveled-Nielsen, L., Sundgreen, C., lassen, J. B. & Hansen, H. H., 2012, In: Obesity.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Central and Peripheral GABA(A) Receptor Regulation of the Heart Rate Depends on the Conscious State of the Animal

    Bentzen, Bo Hjorth & Grunnet, Morten, 2011, In: Advances in Pharmacological Sciences. 2011, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

    Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, R., Folkersen, L., Abildgaard, L., Speerschneider, T., Muthukumarasamy, K. M., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.

    Bentzen, Bo Hjorth, Nardi, A., Callø, Kirstine, Madsen, L. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Molecular Pharmacology. 72, 4, p. 1033-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A comparison of two models of experimental periodontitis in rats

    Bentzen, Bo Hjorth, Grauballe, M. C. B., Björnsson, M. J., Stoltze, K., Hjørting-Hansen, E. & Holmstrup, Palle, 2005, In: Scandinavian Journal of Laboratory Animal Science. 2, p. 73-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Synthesis and characterisation of NS13558: a new important tool for addressing KCa1.1 channel function ex vivo

    Bentzen, Bo Hjorth, Andersen, R. W., Olesen, Søren-Peter, Grunnet, Morten & Nardi, A., 2009, In: NAUNYN-SCHMIEDEBERGS ARCHIV FUR EXPERIMENTELLE PATHOLOGIE UND PHARMAKOLOGIE.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 11 p., 556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Gentilini, F., Forni, M., Zannoni, A., Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, Christian, Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In: Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Multiple genetic variations in sodium channel subunits in a case of sudden infant death syndrome

    Denti, F., Bentzen, Bo Hjorth, Wojciak, J., Thomsen, N. M., Scheinman, M. & Schmitt, Nicole, 2018, In: Pacing and Clinical Electrophysiology. 41, 6, p. 620-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Role of calcium activated potassium channels in atrial fibrillation pathophysiology and therapy

    Diness, Jonas Goldin, Bentzen, Bo Hjorth, S. Sørensen, U. & Grunnet, Morten, Nov 2015, In: Journal of Cardiovascular Pharmacology. 66, 5, p. 441-448 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

    Diness, J. G., Kirchhoff, J. E., Speerschneider, T., Abildgaard, L., Edvardsson, N., Sorensen, U. S., Grunnet, Morten & Bentzen, Bo Hjorth, 2020, In: Frontiers in Pharmacology. 11, 9 p., 159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

    Ewart, G., Bobardt, M., Bentzen, Bo Hjorth, Yan, Y., Thomson, A., Klumpp, K., Becker, S., Rosenkilde, Mette, Miller, M. & Gallay, P., 2023, In: PLoS Pathogens. 19, 8 August, 20 p., e1011328.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction

    Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Increased Density of Endogenous Adenosine A2A Receptors in Atrial Fibrillation: From Cellular and Porcine Models to Human Patients

    Godoy-Marín, H., Jiménez-Sábado, V., Tarifa, C., Ginel, A., Santos, J. L. D., Bentzen, Bo Hjorth, Hove-Madsen, L. & Ciruela, F., 2023, In: International Journal of Molecular Sciences. 24, 4, 11 p., 3668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The effect of spironolactone on experimental periodontitis in rats

    Grauballe, M. C. B., Bentzen, Bo Hjorth, Bjørnson, M., Moe, D., Jonassen, K., Bendtzen, K. & Holmstrup, Palle, 2003.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  23. Published

    Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants

    Gregers, E., Ahlberg, G., Christensen, T., Jabbari, J., Larsen, K. O., Herfelt, C. B., Henningsen, K. M., Andreasen, Laura Korsholm, Thiis, J. J., Lund, J., Holme, S., Haunsø, Stig, Bentzen, Bo Hjorth, Schmitt, Nicole, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, Oct 2017, In: Heart Rhythm. 14, 10, p. 1531-1538

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cardiac ion channels and mechanisms for protection against atrial fibrillation.

    Grunnet, Morten, Bentzen, Bo Hjorth, Sørensen, U. S. & Diness, Jonas Goldin, 2011, In: Reviews of Physiology, Biochemistry and Pharmacology. 162, p. 1-58 59 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders

    Grupe, M., Bentzen, Bo Hjorth, Benned-Jensen, T., Nielsen, V., Frederiksen, K., Jensen, H. S., Jacobsen, A., Skibsbye, L., Sams, A. G., Grunnet, M., Rottlander, M. & Bastlund, J. F., 2020, In: European Journal of Pharmacology. 887, 12 p., 173440.

    Research output: Contribution to journalJournal articleResearchpeer-review

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