Cathrine Ørskov
Head of Department
Endocrinology and Metabolism
Blegdamsvej 3, Building: 12-4-20
2200 København N
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GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.
Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539Research output: Contribution to journal › Journal article › Research › peer-review
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All products of proglucagon are elevated in plasma from ureamic patients
Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1, a new hormone of the enteroinsular axis
Ørskov, Cathrine, 1992, In: Diabetologia. 35, p. 701-711Research output: Contribution to journal › Journal article › Research › peer-review
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Typical Danish Caucasian type 2 diabetic patients do not commonly carry germ line mutations in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
Ørskov, Cathrine, Hjorth, S. A., Jensen, A. D. & Vilsbøll, T., 2004, In: Regul. Pept.. 119, p. 151-154Research output: Contribution to journal › Journal article › Research › peer-review
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Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans
Ørskov, Cathrine & Poulsen, S. S., 1991, In: Diabetes, The American Diabetes Association. Vol 40, no.10, p. 1292-1296Research output: Contribution to journal › Journal article › Research › peer-review
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Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract
Ørskov, Cathrine & Holst, Jens Juul, 2000, Nitric Oxide and the Peripheral Nervous System. London, UK: Portland Press Ltd., p. 131Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas
de Heer, J., Pedersen, J., Ørskov, Cathrine & Holst, Jens Juul, Oct 2007, In: Diabetologia. 50, 10, p. 2135-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targets and tactics: the relative importance of HbA, fasting and postprandial plasma glucose levels to glycaemic control in type 2 diabetes
Woo, V., Shestakova, M. V., Ørskov, Cathrine & Ceriello, A., Dec 2008, In: International Journal of Clinical Practice. 62, 12, p. 1935-42 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, , 2020, In: Molecular Metabolism. 42, 18 p., 101080.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.
Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal-jejunal transposition or small bowel resection
Thulesen, J., Hartmann, B., Kissow, H., Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46 (2), p. 379-388Research output: Contribution to journal › Journal article › Research › peer-review
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The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.
Thulesen, J., Knudsen, L. B., Hartmann, B., Hastrup, S., Kissow, Hannelouise, Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2002, In: Regulatory Peptides. 103, 1, p. 9-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2
Thulesen, J., Hartmann, B., Ørskov, Cathrine, Jeppesen, P. B., Holst, Jens Juul & Poulsen, Steen Seier, 2000, In: Peptides. 10, p. 1511-1517Research output: Contribution to journal › Journal article › Research › peer-review
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Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice
Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection
Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2
Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Release of PYY from pig intestinal mucosa; luminal and neural regulation
Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide has tonic inhibitory effect, byt is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, J. J., 2003, In: Scandinavian Journal of Gastroenterology. Vol. 38, p. 955-61Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, Jens Juul, Sep 2003, In: Scandinavian Journal of Gastroenterology. 38, 9, p. 955-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans
Schjoldager, B. T., Mortensen, P. E., Christiansen, J., Ørskov, Cathrine & Holst, Jens Juul, May 1989, In: Digestive Diseases and Sciences. 34, 5, p. 703-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological evidence for CGRP uptake into perivascular capsaicin sensitive nerve terminals
Sams-Nielsen, A., Ørskov, Cathrine & Jansen-Olesen, I., Mar 2001, In: British Journal of Pharmacology. 132, 5, p. 1145-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships
Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725Research output: Contribution to journal › Journal article › Research › peer-review
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The expression of peptide hormones in normal cells and tumour cells
Rehfeld, Jens Frederik, Bardram, L., Blanke, S., Cantor, P., Friis-Hansen, Lennart Jan, Hilsted, Linda, Johnsen, A. H., Monstein, H. J., Van Solinge, W. W., Ødum, L. & Ørskov, Cathrine, 1991, In: Acta Oncologica. 30, 4, p. 429-433 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
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Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody
Pyke, C., Heller, R. S., Kirk, R. K., Ørskov, Cathrine, Reedtz-Runge, S., Kaastrup, P., Hvelplund, A., Bardram, L., Calatayud, D. & Knudsen, L. B., Apr 2014, In: Endocrinology. 155, 4, p. 1280-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans
Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, , 2023, In: npj Aging. 9, 21 p., 7.Research output: Contribution to journal › Journal article › Research › peer-review
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Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 does not not acutely affect insulin sensitivity in healthy man
Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans. Autoradiographic survey of extracerebral tissues in rats
Ørskov, Cathrine & Poulsen, Steen Seier, Oct 1991, In: Diabetes. 40, 10, p. 1292-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Truncated glucagon-like peptide-1 (proglucagon 78-107 amide), an intestinal insulin-releasing peptide, has specific receptors on rat insulinoma cells (RIN 5AH)
Ørskov, Cathrine & Nielsen, Jens Høiriis, 29 Feb 1988, In: FEBS Letters. 229, 1, p. 175-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
Ørskov, Cathrine, Holst, Jens Juul & Nielsen, O. V., Oct 1988, In: Molecular Endocrinology. 123, 4, p. 2009-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine
Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complete sequences of glucagon-like peptide-1 from human and pig small intestine
Ørskov, Cathrine, Bersani, M., Johnsen, A. H., Højrup, P. & Holst, Jens Juul, 5 Aug 1989, In: The Journal of Biological Chemistry. 264, 22, p. 12826-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)
Ørskov, Cathrine & Holst, Jens Juul, Apr 1987, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 47, 2, p. 165-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, a new hormone of the entero-insular axis
Ørskov, Cathrine, Aug 1992, In: Diabetologia. 35, 8, p. 701-11 11 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 137086045
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In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae
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Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
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No direct effect of SGLT2 activity on glucagon secretion
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