Bo Hjorth Bentzen

Bo Hjorth Bentzen

Associate Professor


  1. 2015
  2. Published

    Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel

    Liin, S. I., Silverå Ejneby, M., Barro-Soria, R., Skarsfeldt, M. A., Larsson, J. E., Starck Härlin, F., Parkkari, T., Bentzen, Bo Hjorth, Schmitt, Nicole, Larsson, H. P. & Elinder, F., 5 May 2015, In: Proceedings of the National Academy of Science of the United States of America. 112, 18, p. 5714–5719 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

    Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

    Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Role of calcium activated potassium channels in atrial fibrillation pathophysiology and therapy

    Diness, Jonas Goldin, Bentzen, Bo Hjorth, S. Sørensen, U. & Grunnet, Morten, Nov 2015, In: Journal of Cardiovascular Pharmacology. 66, 5, p. 441-448 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2016
  7. Published

    Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes

    Liin, S. I., Karlsson, U., Bentzen, Bo Hjorth, Schmitt, Nicole & Elinder, F., 23 Feb 2016, In: Acta Physiologica (Print). 218, 1, p. 28-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

    Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations

    Liin, S. I., Larsson, J. E., Barro-Soria, R., Bentzen, Bo Hjorth & Larsson, H. P., 30 Sep 2016, In: eLife. 5, 19 p., e20272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2017
  12. Published

    Novel negative allosteric modulator inhibits small conductance calcium-activated potassium channels and selectively prolongs atrial refractoriness in conscious pigs

    Simó-Vicens, R., Citerni, C., Edvardsson, N. G., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 11 May 2017, In: Heart Rhythm. 14, 5 suppl., p. S149-S150 P-PO02-15.

    Research output: Contribution to journalConference abstract in journalResearch

  13. Published

    Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels

    Simo Vicens, R., Sauter, D. R. P., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 15 May 2017, In: European Journal of Pharmacology. 803, p. 118-123 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants

    Gregers, E., Ahlberg, G., Christensen, T., Jabbari, J., Larsen, K. O., Herfelt, C. B., Henningsen, K. M., Andreasen, Laura Korsholm, Thiis, J. J., Lund, J., Holme, S., Haunsø, Stig, Bentzen, Bo Hjorth, Schmitt, Nicole, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, Oct 2017, In: Heart Rhythm. 14, 10, p. 1531-1538

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels

    Simo Vicens, R., Kirchhoff, J. E., Dolce , B., Abildgaard, L., Speerschneider, T., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 5 Dec 2017, In: British Journal of Pharmacology. 174, 23, p. 4396-4408 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    Multiple genetic variations in sodium channel subunits in a case of sudden infant death syndrome

    Denti, F., Bentzen, Bo Hjorth, Wojciak, J., Thomsen, N. M., Scheinman, M. & Schmitt, Nicole, 2018, In: Pacing and Clinical Electrophysiology. 41, 6, p. 620-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

    Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, Christian, Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In: Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization

    Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Homozygosity for SCN4A Arg1142Gln causes congenital myopathy with variable disease expression

    Sloth, C. K., Denti, F., Schmitt, Nicole, Bentzen, Bo Hjorth, Fagerberg, C., Vissing, John & Gaist, D., Oct 2018, In: Neurology: Genetics. 4, 5, p. e267 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer

    Jensen, K., Skarsfeldt, M. A., Stærkind, Hans, Arnbak, J., Balabas, M. V., Olesen, Søren-Peter, Bentzen, Bo Hjorth & Polzik, Eugene Simon, 1 Nov 2018, In: Scientific Reports. 8, 9 p., 16218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels

    Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2019
  26. Published

    The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

    Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2020
  28. Published

    Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Gentilini, F., Forni, M., Zannoni, A., Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Functional phenotype variations of two novel Kv 7.1 mutations identified in patients with Long QT syndrome

    Bomholtz, Sofia Hammami, Refaat, M., Steffensen, Annette Buur, David, J., Espinosa, K., Nussbaum, R., Wojciak, J., Bentzen, Bo Hjorth, Scheinman, M. & Schmitt, Nicole, 2020, In: Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders

    Grupe, M., Bentzen, Bo Hjorth, Benned-Jensen, T., Nielsen, V., Frederiksen, K., Jensen, H. S., Jacobsen, A., Skibsbye, L., Sams, A. G., Grunnet, M., Rottlander, M. & Bastlund, J. F., 2020, In: European Journal of Pharmacology. 887, 12 p., 173440.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation

    Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13529