Morten Steen Salling Olesen
Professor MSO
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3
2200 København N.
- 2022
- Published
Association of Common and Rare Genetic Variation in the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
Ghouse, Jonas, Ahlberg, Gustav, Skov, A. G., Bundgård, Henning & Olesen, Morten Steen Salling, 2022, In: Journal of the American Heart Association. 11, 12, p. 1-39 e025361.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles - A Mendelian randomization analysis
Helgadottir, A., Thorleifsson, G., Snaebjarnarson, A., Stefansdottir, L., Sveinbjornsson, G., Tragante, V., Björnsson, E., Steinthorsdottir, V., Gretarsdottir, S., Helgason, H., Saemundsdottir, J., Olafsson, I., Thune, J. J., Axelsson Raja, A., Ghouse, J., Olesen, M. S., Christensen, A., Jacobsen, R. L., Dowsett, J., Bruun, M. T. & 18 others, , 2022, In: European Journal of Preventive Cardiology. 29, 18, p. 2374–2385Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population.
Paludan-Müller, Christian, Larsen, S., Ahlberg, G., Monfort, L. M., Andreasen, L., Svendsen, Jesper Hastrup, Jespersen, Thomas, Bundgård, Henning, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2022, In: Circulation. Genomic and precision medicine. 15, 1, p. 83-85 3 p., e003574.Research output: Contribution to journal › Letter › Research › peer-review
- Published
DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine
Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).Research output: Working paper › Preprint
- Published
Effect of Loss-of-Function Genetic Variants in PCSK9 on Glycemic Traits, Neurocognitive Impairment, and Hepatobiliary Function
Ghouse, Jonas, Ahlberg, G., Bundgård, Henning & Olesen, Morten Steen Salling, 2022, In: Diabetes Care. 45, 1, p. 251-254Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrocardiographic Findings, Arrhythmias, and Left Ventricular Involvement in Familial ST-Depression Syndrome
Christensen, Alex Hørby, Vissing, C. R., Pietersen, A., Tfelt-Hansen, Jacob, Jensen, Thomas Hartvig Lindkær, Pehrson, S., Henriksen, F. L., Sandgaard, N. C. F., Iversen, Kasper, Jensen, H. K., Olesen, Morten Steen Salling & Bundgård, Henning, 2022, In: Circulation. Arrhythmia and electrophysiology. 15, 4, p. 231-240 e010688.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fascicular heart blocks and risk of adverse cardiovascular outcomes: Results from a large primary care population
Nyholm, B. C., Ghouse, J., Lee, C. J. Y., Rasmussen, P. V., Pietersen, A., Hansen, S. M., Torp-Pedersen, Christian, Køber, Lars Valeur, Haunsø, Stig, Olesen, Morten Steen Salling, Svendsen, Jesper Hastrup, Graff, C., Holst, A. G., Nielsen, J. B. & Skov, M. W., 2022, In: Heart Rhythm. 19, 2, p. 252-259 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT
Andreasen, L., Ahlberg, G., Ægisdóttir, H. M., Sveinbjörnsson, G., Lundegaard, P. R., Hartmann, J. P., Paludan-Müller, C., Hadji-Turdeghal, K., Ghouse, J., Pehrson, S., Jensen, H. K., Riahi, S., Hansen, J., Sandgaard, N., Sørensen, E., Banasik, K., Sækmose, S. G., Bruun, M. T., Hjalgrim, H., Erikstrup, C. & 18 others, , 2022, In: Circulation Research. 131, 10, p. 862-865Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 31 others, , 2022, In: Nature Communications. 13, 1, 18 p., 5144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Left Atrial Remodeling and Cerebrovascular Disease Assessed by Magnetic Resonance Imaging in Continuously Monitored Patients
Bertelsen, L., Diederichsen, S. Z., Frederiksen, K. S., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Højberg, S., Olesen, Morten Steen Salling, Biering-Sørensen, Tor, Køber, Lars Valeur, Vejlstrup, N., Hasselbalch, Steen & Svendsen, Jesper Hastrup, 2022, In: Cerebrovascular Diseases. 51, 3, p. 403–412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci
Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, , 2022, In: European Heart Journal. 43, 45, p. 4707–4718Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severity and Etiology of Incident Stroke in Patients Screened for Atrial Fibrillation vs Usual Care and the Impact of Prior Stroke: A Post Hoc Analysis of the LOOP Randomized Clinical Trial
Diederichsen, S. Z., Frederiksen, K. S., Xing, L. Y., Haugan, K. J., Højberg, S., Brandes, A., Graff, C., Olesen, Morten Steen Salling, Krieger, D., Køber, Lars Valeur & Svendsen, Jesper Hastrup, 2022, In: JAMA Neurology. 79, 10, p. 997-1004Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation
Vad, Oliver Tim Bundgaard, Yan, Y., Denti, F., Ahlberg, Gustav, Refsgaard, L., Bomholtz, Sofia Hammami, Santos, J. L., Rasmussen, Simon, Haunsø, Stig, Svendsen, Jesper Hastrup, Christophersen, I. E., Schmitt, Nicole, Olesen, Morten Steen Salling & Bentzen, Bo Hjorth, 2022, In: Frontiers in Genetics. 13, 8 p., 806429.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between primary care electrocardiography and non-Alzheimer dementia
Isaksen, Jonas L., Ghouse, Jonas, Skov, M. W., Olesen, Morten Steen Salling, Holst, A. G., Pietersen, A., Nielsen, J. B., Maier, A. M., Graff, C., Frikke-Schmidt, Ruth & Kanters, Jørgen K., 10 Jul 2022, In: Journal of Stroke & Cerebrovascular Diseases. 31, 9, 7 p., 106640.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Association between primary care electrocardiogram markers and Alzheimer's disease
Isaksen, Jonas L., Ghouse, Jonas, Skov, M. W., Olesen, Morten Steen Salling, Holst, A. G., Pietersen, A., Nielsen, J. B., Maier, A., Graff, C., Gerds, Thomas Alexander, Frikke-Schmidt, Ruth & Kanters, Jørgen K., 2023, In: Journal of the Neurological Sciences. 447, 6 p., 120581.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of PCSK9 Loss-of-Function Variants With Risk of Heart Failure
Trudso, L. C. C., Ghouse, Jonas, Ahlberg, G., Bundgård, Henning & Olesen, Morten Steen Salling, 2023, In: JAMA Cardiology. 8, 2, p. 159-166Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CineECG analysis provides new insights into Familial ST-segment Depression Syndrome
Frosted, R., Paludan-Müller, Christian, Vad, Oliver Tim Bundgaard, Olesen, Morten Steen Salling, Bundgård, Henning, van Dam, P. & Christensen, Alex Hørby, 2023, In: Europace. 25, 5, 11 p., euad116.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex effects of sequence variants on lipid levels and coronary artery disease
Snaebjarnarson, A. S., Helgadottir, A., Arnadottir, G. A., Ivarsdottir, E. V., Thorleifsson, G., Ferkingstad, E., Einarsson, G., Sveinbjornsson, G., Thorgeirsson, T. E., Ulfarsson, M. O., Halldorsson, B. V., Olafsson, I., Erikstrup, C., Pedersen, O. B., Nyegaard, M., Bruun, M. T., Ullum, H., Brunak, S., Iversen, K. K., Christensen, A. H. & 14 others, , 2023, In: Cell. 186, 19, p. 4085-4099.e15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study
Wells, Q. S., Söderberg, S., Stefánsson, K., Schott, J., Rader, D. J., Clarke, R., Engert, J. C., Thanassoulis, G. & Therapeutic targets for AoRtic stenosis using GEneTics (TARGET) Consortium, T. T. F. A. S. U. G. (. C., 2023, In: European Heart Journal. 44, 21, p. 1927-1939 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study
Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: Circulation. 147, 24, p. 1788-1797 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrocardiographic Morphology-Voltage-P-Wave-Duration (MVP) Score to Select Patients for Continuous Atrial Fibrillation Screening to Prevent Stroke
Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D., Graff, C., Olesen, Morten Steen Salling, Nielsen, J. B., Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: American Journal of Cardiology. 205, p. 457-464 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study
Xing, L. Y., Diederichsen, S. Z., Hojberg, S., Krieger, D. W., Graff, C., Olesen, Morten Steen Salling, Nielsen, J. B., Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: Europace. 25, 5, 10 p., euad014.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically predicted adipose tissue distribution influences the risk of atherosclerosis
Vad, Oliver Tim Bundgaard, Paludan-Müller, Christian, Monfort, L. M., Ahlberg, Gustav, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2023, In: European Journal of Preventive Cardiology. 30, 7, p. e41–e45Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism
Ghouse, J., Tragante, V., Ahlberg, G., Rand, S. A., Jespersen, J. B., Leinøe, E. B., Vissing, C. R., Trudsø, L., Jonsdottir, I., Banasik, K., Brunak, S., Ostrowski, S. R., Pedersen, O. B., Sørensen, E., Erikstrup, C., Bruun, M. T., Nielsen, K. R., Køber, L., Christensen, A. H., Iversen, K. & 16 others, , 2023, In: Nature Genetics. 55, p. 399-409 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for atrial fibrillation to prevent stroke in elderly individuals with or without preexisting cardiovascular disease: A post hoc analysis of the randomized LOOP Study
Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: International Journal of Cardiology. 370, p. 197-203 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, , 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Atrial Cardiomyopathies: Common Features, Specific Differences, and Broader Relevance to Understanding Atrial Cardiomyopathy
Marcoux, E., Sosnowski, D., Ninni, S., MacKasey, M., Cadrin-Tourigny, J., Roberts, J. D., Olesen, Morten Steen Salling, Fatkin, D. & Nattel, S., Dec 2023, In: Circulation: Arrhythmia and Electrophysiology. 16, 12, p. 675-698Research output: Contribution to journal › Review › Research › peer-review
- 2024
- Published
A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation
Yfanti, C., Vestbjerg, B., van't Westende, J., Edvardsson, N., Monfort, L. M., Olesen, Morten Steen Salling, Bentzen, Bo Hjorth, Grunnet, Morten, Eveleens Maarse, B. C., Diness, Jonas Goldin, Kemme, M. J. B., Sørensen, U., Moerland, M., van Esdonk, M. J., Klaassen, E. S., Gal, P. & Holst, A. G., 2024, In: British Journal of Clinical Pharmacology. 90, 4, p. 1027-1035Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of DIO2 and MCT10 Polymorphisms With Persistent Symptoms in LT4-Treated Patients in the UK Biobank
Jensen, Christian Zinck, Isaksen, Jonas L., Ahlberg, Gustav, Olesen, Morten Steen Salling, Nygaard, Birte, Ellervik, Christina & Kanters, Jørgen K., 2024, In: The Journal of clinical endocrinology and metabolism. 109, 2, p. e613-e622 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epicardial adipose tissue and subclinical incident atrial fibrillation as detected by continuous monitoring: a cardiac magnetic resonance imaging study
Guldberg, E., Diederichsen, S. Z., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Olesen, Morten Steen Salling, Højberg, S., Køber, Lars Valeur, Vejlstrup, N., Bertelsen, L. & Svendsen, Jesper Hastrup, 2024, In: International Journal of Cardiovascular Imaging. 40, p. 591–599Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, , 2024, In: Nature Genetics. 56, p. 827–837 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation
Vad, Oliver Tim Bundgaard, Angeli, Elisavet, Liss, M., Ahlberg, Gustav, Andreasen, Laura Korsholm, Christophersen, I. E., Hansen, Camilla Collin, Møller, S., Hellsten, Ylva, Haunsø, Stig, Tveit, A., Svendsen, Jesper Hastrup, Gotthardt, M., Lundegaard, Pia Rengtved & Olesen, Morten Steen Salling, 2024, In: JACC: Basic to Translational Science. 9, 2, p. 163-180Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, , 2024, In: Nature Communications. 15, 1, 18 p., 888.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential Influence of Risk Factor Control on the Association between Lipoprotein(a) and Atherosclerotic Cardiovascular Disease
Ghouse, Jonas, Ahlberg, G., Rand, S. A., Olesen, Morten Steen Salling, Vilhjalmsson, B., Stender, Stefan & Bundgård, Henning, 2024, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 44, 6, p. 1455-1457Research output: Contribution to journal › Letter › Research › peer-review
- Published
Presence of Atrioventricular Nodal Reentrant Tachycardia Is Associated With Cardiomyopathy, Heart Failure, and Death
Paludan-Müller, Christian, Stampe, N. K., Monfort, L. M., Andreasen, L., Vad, Oliver Tim Bundgaard, Ahlberg, Gustav, Johansen, J. B., Winkel, B. G., Torp-Pedersen, Christian, Køber, Lars Valeur, Fosbøl, Emil Loldrup, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2024, In: Journal of the American Heart Association. 13, 9, 4 p., e034439.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tackling a growing healthcare challenge: atrial fibrillation epidemiology, prevention, and underlying causes
Vad, Oliver Tim Bundgaard, Paludan-Müller, Christian, Diederichsen, S. Z. & Olesen, Morten Steen Salling, 2024, In: The Lancet Regional Health - Europe. 37, 2 p., 100827.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The ABC-Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study
Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Platonov, P. G., Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2024, In: Journal of the American Heart Association. 13, 4, 12 p., e032744.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Unlocking the Genetic Code: Novel Insights Into Familial Atrial Fibrillation and Gene-Variant Interactions
Vad, Oliver Tim Bundgaard & Olesen, Morten Steen Salling, 2024, (E-pub ahead of print) In: Canadian Journal of Cardiology.Research output: Contribution to journal › Editorial › Research › peer-review
ID: 49763464
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225
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Effect of diabetes duration on the relationship between glycaemic control and risk of death in older adults with type 2 diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
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192
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Electrocardiographic Precordial ST‐Segment Deviations and the Risk of Cardiovascular Death: Results From the Copenhagen ECG Study
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
192
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Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
Research output: Contribution to journal › Journal article › Research › peer-review
Published