Bo Hjorth Bentzen
Associate Professor
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3
2200 København N.
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A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels
Simo Vicens, R., Kirchhoff, J. E., Dolce , B., Abildgaard, L., Speerschneider, T., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 5 Dec 2017, In: British Journal of Pharmacology. 174, 23, p. 4396-4408 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel negative allosteric modulator inhibits small conductance calcium-activated potassium channels and selectively prolongs atrial refractoriness in conscious pigs
Simó-Vicens, R., Citerni, C., Edvardsson, N. G., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 11 May 2017, In: Heart Rhythm. 14, 5 suppl., p. S149-S150 P-PO02-15.Research output: Contribution to journal › Conference abstract in journal › Research
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2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels
Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.Research output: Contribution to journal › Journal article › Research › peer-review
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Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization
Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.Research output: Contribution to journal › Journal article › Research › peer-review
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pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts
Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness
Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.Research output: Contribution to journal › Journal article › Research › peer-review
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Polyunsaturated fatty acid-derivedI(Ks)channel activators shorten the QT interval ex-vivo and in-vivo
Skarsfeldt, M. A., Liin, S. I., Larsson, H. P. & Bentzen, Bo Hjorth, 2020, In: Acta Physiologica. 229, 4, 10 p., 13471.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium
Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Homozygosity for SCN4A Arg1142Gln causes congenital myopathy with variable disease expression
Sloth, C. K., Denti, F., Schmitt, Nicole, Bentzen, Bo Hjorth, Fagerberg, C., Vissing, John & Gaist, D., Oct 2018, In: Neurology: Genetics. 4, 5, p. e267 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation
Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury
Soltysinska, E., Bentzen, B. H., Barthmes, M., Hattel, H., Thrush, A. B., Harper, M-E., Qvortrup, K., Larsen, F. J., Schiffer, T. A., Losa-Reyna, J., Straubinger, J., Kniess, A., Thomsen, M. B., Brüggemann, A., Fenske, S., Biel, M., Ruth, P., Wahl-Schott, C., Boushel, R. C., Olesen, S-P. & 1 others, , 2014, In: PLOS ONE. 9, 7, p. 1-12 12 p., e103402.Research output: Contribution to journal › Journal article › Research › peer-review
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Viroporiners potentiale som lægemiddeltargets med fokus på SARS-CoV-2
Sund, J. D., Bollerup, S., Glamann, J. B., Vinten, C. A., Jensen, L. R., Toft-Bertelsen, Trine Lisberg, Bentzen, Bo Hjorth, Kledal, T. N., Weis, Nina & Rosenkilde, M., 13 Jun 2022, In: Ugeskrift for Laeger. 184, 24, 8 p., V02220103.Research output: Contribution to journal › Review › Research › peer-review
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Benzimidazolyl-acetamide derivatives useful as potassium channel modulators
SØRENSEN, U. S., Grunnet, Morten, Bentzen, Bo Hjorth, Christophersen, P., Diness, Jonas Goldin, SKIBSBYE, L. & Strøbæk, D., 7 Jan 2013Research output: Other contribution › Research
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Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms
Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to: How Many SARS-CoV-2 "Viroporins" Are Really Ion Channels? [Inkl. Correction]
Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Landbrug, A., Mujezinovic, A., Bentzen, Bo Hjorth, Kledal, T. N. & Rosenkilde, Mette, 2022, In: Communications Biology . 5, 1, 1 p., 860.Research output: Contribution to journal › Letter › Research › peer-review
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Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro
Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Tzortzini, E., Xue, K., Giller, K., Becker, S., Mujezinovic, A., Bentzen, Bo Hjorth, Andreas, L. B., Kolocouris, A., Kledal, T. N. & Rosenkilde, Mette, 2021, In: Communications Biology. 4, 10 p., 1347.Research output: Contribution to journal › Journal article › Research › peer-review
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Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation
Vad, Oliver Tim Bundgaard, Yan, Y., Denti, F., Ahlberg, Gustav, Refsgaard, L., Bomholtz, Sofia Hammami, Santos, J. L., Rasmussen, Simon, Haunsø, Stig, Svendsen, Jesper Hastrup, Christophersen, I. E., Schmitt, Nicole, Olesen, Morten Steen Salling & Bentzen, Bo Hjorth, 2022, In: Frontiers in Genetics. 13, 8 p., 806429.Research output: Contribution to journal › Journal article › Research › peer-review
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Small conductance calcium activated K+ channel inhibitor decreases stretch induced vulnerability to atrial fibrillation
Yan, Y., Skarsfeldt, M. A., Diness, Jonas Goldin & Bentzen, Bo Hjorth, 2021, In: IJC Heart and Vasculature. 37, 8 p., 100898.Research output: Contribution to journal › Journal article › Research › peer-review
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A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation
Yfanti, C., Vestbjerg, B., van't Westende, J., Edvardsson, N., Monfort, L. M., Olesen, Morten Steen Salling, Bentzen, Bo Hjorth, Grunnet, Morten, Eveleens Maarse, B. C., Diness, Jonas Goldin, Kemme, M. J. B., Sørensen, U., Moerland, M., van Esdonk, M. J., Klaassen, E. S., Gal, P. & Holst, A. G., 2024, In: British Journal of Clinical Pharmacology. 90, 4, p. 1027-1035Research output: Contribution to journal › Journal article › Research › peer-review
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Gating kinetics and pharmacological properties of small-conductance Ca2+-activated potassium channels
van Herck, I. G. M., Seutin, V., Bentzen, Bo Hjorth, Marrion, N. V. & Edwards, A. G., 4 Apr 2023, In: Biophysical Journal. 122, 7, p. 1143-1157 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13529
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
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350
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Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
253
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Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer
Research output: Contribution to journal › Journal article › Research › peer-review
Published