Semimacroscopic examinations of the surface pattern of small intestinal mucosa in Crohn's disease
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Semimacroscopic examinations of the surface pattern of small intestinal mucosa in Crohn's disease. / Poulsen, Steen Seier.
In: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 83, No. 4, 07.1975, p. 379-88.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Semimacroscopic examinations of the surface pattern of small intestinal mucosa in Crohn's disease
AU - Poulsen, Steen Seier
PY - 1975/7
Y1 - 1975/7
N2 - The mucosal surface pattern of surgical specimens from small intestine affected by Crohn's disease are studied using Alcian-green staining of whole mounts. The semimacroscopic appearance of the mucosa is described. Our findings include i.a. malformation and enlargement of villi-often to extreme degree-villi frequently showing small vesicles on their apical region. Polypoid structures were found to be avillous as well as covered by normal or abnormal villi. The semimacroscopic observations are compared with observations from conventional light microscopy. The villus enlargement is in the first stages caused by lymphatic dilatation and later by oedema and inflammation.
AB - The mucosal surface pattern of surgical specimens from small intestine affected by Crohn's disease are studied using Alcian-green staining of whole mounts. The semimacroscopic appearance of the mucosa is described. Our findings include i.a. malformation and enlargement of villi-often to extreme degree-villi frequently showing small vesicles on their apical region. Polypoid structures were found to be avillous as well as covered by normal or abnormal villi. The semimacroscopic observations are compared with observations from conventional light microscopy. The villus enlargement is in the first stages caused by lymphatic dilatation and later by oedema and inflammation.
KW - Adolescent
KW - Adult
KW - Biopsy
KW - Crohn Disease
KW - Humans
KW - Ileum
KW - Intestinal Mucosa
KW - Intestine, Small
M3 - Journal article
C2 - 1155104
VL - 83
SP - 379
EP - 388
JO - Acta Pathologica et Microbiologica Scandinavica - Section A Pathology
JF - Acta Pathologica et Microbiologica Scandinavica - Section A Pathology
SN - 0365-4184
IS - 4
ER -
ID: 47490303