Department of Biomedical Sciences

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  1. 2023
  2. Published

    Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival

    Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cryo-EM structure of the trehalose monomycolate transporter, MmpL3, reconstituted into peptidiscs

    Couston, J., Guo, Zongxin, Wang, Kaituo, Gourdon, Pontus Emanuel & Blaise, M., 2023, In: Current Research in Structural Biology. 6, 100109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Achilles Tendon Tissue Turnover Before and Immediately After an Acute Rupture

    Cramer, A., Højfeldt, Grith Stougaard, Schjerling, Peter, Agergaard, J., van Hall, Gerrit, Olsen, J., Hölmich, Per, Kjær, Michael & Barfod, Kristoffer Weisskirchner, 2023, In: American Journal of Sports Medicine. 51, 9, 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Levels of type XVII collagen (BP180) ectodomain are elevated in circulation from patients with multiple cancer types and is prognostic for patients with metastatic colorectal cancer

    Crespo Bravo, Marina, Thorlacius-Ussing, J., Nissen, N. I., Pedersen, Rasmus Sund, Boisen, M. K., Liljefors, M., Johansen, A. Z., Johansen, Julia Sidenius, Karsdal, M. A. & Willumsen, N., 2023, In: BMC Cancer. 23, 1, 12 p., 949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity

    Crombie, E. M., Kim, S., Adamson, S., Dong, H., Lu, T. C., Wu, Y., Wu, Y., Levy, Y., Stimple, N., Lam, W. M. R., Hey, H. W. D., Withers, D. J., Hsu, A. L., Bay, B. H., Ochala, Julien & Tsai, S. Y., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 198–213

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Non-invasive methods to assess muscle function in dogs: A scoping review

    Dahl, Kathrine Højte, Zebis, Mette Kreutzfeldt, Vitger, Anne Désiré, Miles, James Edward & Alkjær, Tine, 2023, In: Frontiers in Veterinary Science. 10, p. 1-10 1116854.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms

    Dam, G., Grønbæk, H., Sundlöv, A., Botling, J., Sundin, A., Petersen, René Horsleben, Welin, S., Evensen, E., Sorbye, H., Tabaksblat, E., Arveschoug, A. K., Mortensen, Jann, Kjær, Andreas, Knigge, Ulrich, Tiensuu Janson, E. & Langer, Seppo W., 16 May 2023, In: Acta Oncologica. 62, 5, p. 431-437 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice

    Daradoumis, J., Ragonnaud, Emeline, Skandorff, I., Nielsen, K. N., Bermejo, A. V., Andersson, A. M., Schroedel, S., Thirion, C., Neukirch, Lasse & Holst, Peter Johannes, 2023, In: Viruses. 15, 4, 26 p., 926.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor

    Deschaine, S. L., Hedegaard, M. A., Pince, C. L., Farokhnia, M., Moose, J. E., Stock, I. A., Adusumalli, S., Akhlaghi, F., Hougland, J. L., Sulima, A., Rice, K. C., Koob, G. F., Vendruscolo, L. F., Holst, Birgitte & Leggio, L., 2023, In: Journal of Pharmacology and Experimental Therapeutics. 386, 2, p. 117-128 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The usefulness of YouTube videos as a source of information in asthma

    Diers, C. S., Remvig, C., Meteran, H., Thomsen, Simon Francis, Sigsgaard, T., Hoj, S. & Meteran, Howraman, 2023, In: Journal of Asthma. 60, 4, p. 737–743

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers

    Doblas, L., Hägglund, Per Mårten, Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Archives of Biochemistry and Biophysics. 733, 7 p., 109482.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Identification of Glomerular and Plasma Apolipoprotein M as Novel Biomarkers in Glomerular Disease

    Drexler, Y., Molina, J., Elfassy, T., Ma, R., Christoffersen, Christina, Kurano, M., Yatomi, Y., Mariani, L. H., Contreras, G., Merscher, S. & Fornoni, A., 2023, In: Kidney International Reports. 8, 4, p. 884-897

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    In Contrast to Anti-CCP, MMP-Degraded and Citrullinated Vimentin (VICM) Is Both a Diagnostic and a Treatment Response Biomarker

    Drobinski, P. J., Nissen, N. I., Sinkeviciute, D., Willumsen, N., Karsdal, M. A. & Bay-Jensen, A. C., Jan 2023, In: International Journal of Molecular Sciences. 24, 1, 12 p., 321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Erectile Dysfunction Is Associated with Left Ventricular Diastolic Dysfunction: A Systematic Review and Meta-analysis

    Durukan, E., Jensen, C. F. S., Skaarup, K. G., Østergren, Peter Busch, Sønksen, Jens Otto Reimers, Biering-Sørensen, Tor & Fode, Mikkel Mejlgaard, 2023, In: European Urology Focus. 9, 6, p. 903-912 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Left atrial functional measurements’ utility in predicting long-term risk of atrial fibrillation after isolated CABG

    Dyhr, M. R., Olsen, F. J., Lindberg, S., Modin, D., Fritz-Hansen, T., Pedersen, S., Iversen, A., Galatius, S., Jespersen, Thomas, Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Echocardiography. 40, 7, p. 695-702 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension

    Ehlers, T. S., van der Horst, Jennifer, Møller, S., Piil, P. K., Gliemann, Lasse, Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Hellsten, Ylva, 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 2179-2189 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Intramural Purkinje fibers facilitate rapid ventricular activation in the equine heart

    Elbrønd (Bibs), Vibeke Sødring, Thomsen, Morten Bækgaard, Isaksen, Jonas L., Lunde, E. D., Vincenti, S., Wang, T., Tranum-Jensen, Jørgen & Callø, Kirstine, 2023, In: Acta Physiologica. 237, 3, e13925.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Circulating Metabolomic and Lipidomic Signatures Identify a Type 2 Diabetes Risk Profile in Low-Birth-Weight Men with Non-Alcoholic Fatty Liver Disease

    Elingaard-Larsen, L. O., Villumsen, S. O., Justesen, L., Thuesen, Anne Cathrine Baun, Kim, M., Ali, M., Danielsen, E. R., Legido-Quigley, C., van Hall, Gerrit, Hansen, Torben, Ahluwalia, T. S., Vaag, Allan & Brøns, C., 2023, In: Nutrients. 15, 7, 16 p., 1590.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Active Transport and Ocular Distribution of Intravitreally Injected Liposomes

    Eriksen, A. Z., Melander, F., Eriksen, G. D. M., Kempen, Paul Joseph, Kjær, Andreas, Andresen, T. L. & Urquhart, A. J., 2023, In: Translational Vision Science & Technology. 12, 8, p. 1-11 1 p., 20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

    Ewart, G., Bobardt, M., Bentzen, Bo Hjorth, Yan, Y., Thomson, A., Klumpp, K., Becker, S., Rosenkilde, Mette, Miller, M. & Gallay, P., 2023, In: PLoS Pathogens. 19, 8 August, 20 p., e1011328.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Re-routing GPR56 signalling using Gα12/13 G protein chimeras

    Faas, Felix, Nørskov, Amalie, Holst, Peter Johannes, Andersson, A. M., Qvortrup, K., Mathiasen, Signe & Rosenkilde, Mette, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 378-389

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Derivation of Human Extraembryonic Mesoderm-like Cells from Primitive Endoderm

    Farkas, Karin & Ferretti, Elisabetta, 2023, In: International Journal of Molecular Sciences. 24, 14, 19 p., 11366.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells

    Ferreira, F. P., Pereira, S. S., Costa, M. M., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Molecular and Cellular Biochemistry. 478, 12, p. 2779-2787

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Human α-Defensin 51–9 and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet

    Filipe Rosa, L., Rings, A., Stolzer, I., Koeninger, L., Wehkamp, J., Beisner, J., Günther, C., Nordkild, P., Jensen, Benjamin Anderschou Holbech & Bischoff, S. C., 2023, In: International Journal of Molecular Sciences. 24, 18, 23 p., 13878.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle

    Fiorenza, Matteo, Onslev, J., Henriquez-Olguín, Carlos, Jensen, Thomas Elbenhardt, Wojtaszewski, Jørgen F P, Hostrup, Morten & Bangsbo, Jens, 12 Apr 2023, bioRxiv, p. 1-39, 39 p.

    Research output: Working paper › Preprint

  30. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    [68Ga]Ga-NODAGA-E[(cRGDyK)]2 and [64Cu]Cu-DOTATATE PET Predict Improvement in Ischemic Cardiomyopathy

    Follin, Bjarke, Pedersen, Cecilie Høeg, Hunter, I., Bentsen, Simon, Juhl, M., Jensen, Jacob Kildevang, Binderup, Tina, Nielsen, Carsten Haagen, Ripa, Rasmus Sejersten, Kastrup, J., Ekblond, A. & Kjær, Andreas, 2023, In: Diagnostics. 13, 2, 15 p., 268.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

    Foo, C. X., Bartlett, S., Chew, K. Y., Ngo, M. D., Bielefeldt-Ohmann, H., Arachchige, B. J., Matthews, B., Reed, S., Wang, R., Smith, C., Sweet, M. J., Burr, L., Bisht, K., Shatunova, S., Sinclair, J. E., Parry, R., Yang, Y., Lévesque, J. P., Khromykh, A., Rosenkilde, M. M. & 2 others, Short, K. R. & Ronacher, K., 2023, In: The European respiratory journal. 61, 3, 15 p., 2201306.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Complexation of AAPH (2,2′-azobis(2-methylpropionamidine) dihydrochloride) with cucurbit[7]uril enhances the yield of AAPH-derived radicals

    Forero-Girón, A. C., Fuentealba, D., Mariño-Ocampo, N., Gutiérrez-Oliva, S., Herrera, B., Toro-Labbé, A., Fuentes Lemus, Eduardo, Davies, Michael J., Aliaga, M. E. & López-Alarcón, C., 2023, In: Journal of Molecular Liquids. 389, 9 p., 122840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Association Between Intensive vs Standard Blood Pressure Control and Incident Left Ventricular Conduction Disease A Post Hoc Analysis of the SPRINT Randomized Clinical Trial

    Frimodt-Moller, E. K., Vittinghoff, E., Kaur, G., Biering-Sørensen, Tor, Soliman, E. Z. & Marcus, G. M., 2023, In: JAMA Cardiology. 8, 6, p. 612-616 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Lifestyle habits associated with cardiac conduction disease

    Frimodt-Moller, E. K., Soliman, E. Z., Kizer, J. R., Vittinghoff, E., Psaty, B. M., Biering-Sørensen, Tor, Gottdiener, J. S. & Marcus, G. M., 2023, In: European Heart Journal. 44, 12, p. 1058–1066

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Inflammation and Incident Conduction Disease

    Frimodt-Møller, E. K., Gottdiener, J. S., Soliman, E. Z., Kizer, J. R., Vittinghoff, E., Psaty, B. M., Biering-Sørensen, Tor & Marcus, G. M., 2023, In: Journal of the American Heart Association. 12, 1, p. e027247

    Research output: Contribution to journal › Letter › Research › peer-review

  37. Published

    CineECG analysis provides new insights into Familial ST-segment Depression Syndrome

    Frosted, R., Paludan-Müller, Christian, Vad, Oliver Tim Bundgaard, Olesen, Morten Steen Salling, Bundgård, Henning, van Dam, P. & Christensen, Alex Hørby, 2023, In: Europace. 25, 5, 11 p., euad116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, Joachim, 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges

    Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

    Fuentes Lemus, Eduardo, Reyes, J. S., Figueroa, J. D., Davies, Michael J. & López-Alarcón, C., 2023, In: Biochemical Society Transactions. 51, 6, p. 2173–2187

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

    Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness

    Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The structure of model and peptide disulfides markedly affects their reactivity and products formed with singlet oxygen

    Gao, Qing, Grzyb, K., Gamon, Luke Francis, Ogilby, P. R., Pędziński, T. & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 207, p. 320-329

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance

    Gawalko, M., Saljic, Arnela, Li, N., Abu-Taha, I., Jespersen, Thomas, Dr Linz, Dominik Karl, Nattel, S., Heijman, J., Fender, A. & Dobrev, D., 2023, In: Cardiovascular Research. 119, 3, p. 614–630 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Patient motivation and adherence to an on-demand app-based heart rate and rhythm monitoring for atrial fibrillation management: data from the TeleCheck-AF project

    TeleCheck-AF investigators, T. I., 2023, In: European Journal of Cardiovascular Nursing. 22, 4, p. 412–424

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Atrial Fibrillation Detection and Management in Hypertension

    Gawałko, M. & Dr Linz, Dominik Karl, 1 Mar 2023, In: Hypertension. 80, 3, p. 523-533

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Does weight matter in cryoballoon ablation?

    Gawałko, M., Dr Linz, Dominik Karl & Dobrev, D., 2023, In: IJC Heart and Vasculature. 47, 2 p., 101251.

    Research output: Contribution to journal › Editorial › Research › peer-review

  50. Published

    Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

    Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study

    Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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