The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model

Research output: Contribution to journalJournal articleResearchpeer-review

  • Esmaeel Taqi
  • Laurie E Wallace
  • Elaine de Heuvel
  • Prasanth K Chelikani
  • Huiyuan Zheng
  • Hans-Rudolph Berthoud
  • Holst, Jens Juul
  • David L Sigalet
The signals that govern the upregulation of nutrient absorption (adaptation) after intestinal resection are not well understood. A Gastric Roux-en-Y bypass (GRYB) model was used to isolate the relative contributions of direct mucosal stimulation by nutrients, biliary-pancreatic secretions, and systemic enteric hormones on intestinal adaptation in short bowel syndrome.
Original languageEnglish
Book seriesEuropean Journal of Pediatric Surgery. Supplement
Volume45
Issue number5
Pages (from-to)987-95
Number of pages9
ISSN0939-6764
DOIs
Publication statusPublished - 1 May 2010

    Research areas

  • Adaptation, Physiological, Animals, Cell Proliferation, Epidermal Growth Factor, Fibroblast Growth Factor 2, Fibroblast Growth Factor 7, Gastric Bypass, Glucagon-Like Peptide 2, Insulin-Like Growth Factor I, Intestinal Mucosa, Intestine, Small, Male, Random Allocation, Rats, Rats, Sprague-Dawley, Short Bowel Syndrome, Sodium-Glucose Transporter 1

ID: 33939769