Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
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Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives. / Borges, Elton L.; Ignasiak, Marta T.; Velichenko, Yuliia; Perin, Gelson; Hutton, Craig A.; Davies, Michael J.; Schiesser, Carl H.
In: Chemical Communications, Vol. 54, No. 24, 25.03.2018, p. 2990-2993.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
AU - Borges, Elton L.
AU - Ignasiak, Marta T.
AU - Velichenko, Yuliia
AU - Perin, Gelson
AU - Hutton, Craig A.
AU - Davies, Michael J.
AU - Schiesser, Carl H.
PY - 2018/3/25
Y1 - 2018/3/25
N2 - Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.
AB - Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.
U2 - 10.1039/c8cc00565f
DO - 10.1039/c8cc00565f
M3 - Journal article
C2 - 29505059
VL - 54
SP - 2990
EP - 2993
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 24
ER -
ID: 210610293