GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients

Research output: Contribution to journalJournal articleResearchpeer-review

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GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients. / Doessing, Simon; Holm, Lars; Heinemeier, Katja M; Feldt-Rasmussen, Ulla; Schjerling, Peter; Qvortrup, Klaus; Larsen, Jytte O; Nielsen, Rie H; Flyvbjerg, Allan; Kjaer, Michael.

In: European Journal of Endocrinology, Vol. 163, No. 6, 12.2010, p. 853-62.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Doessing, S, Holm, L, Heinemeier, KM, Feldt-Rasmussen, U, Schjerling, P, Qvortrup, K, Larsen, JO, Nielsen, RH, Flyvbjerg, A & Kjaer, M 2010, 'GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients', European Journal of Endocrinology, vol. 163, no. 6, pp. 853-62. https://doi.org/10.1530/EJE-10-0818

APA

Doessing, S., Holm, L., Heinemeier, K. M., Feldt-Rasmussen, U., Schjerling, P., Qvortrup, K., Larsen, J. O., Nielsen, R. H., Flyvbjerg, A., & Kjaer, M. (2010). GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients. European Journal of Endocrinology, 163(6), 853-62. https://doi.org/10.1530/EJE-10-0818

Vancouver

Doessing S, Holm L, Heinemeier KM, Feldt-Rasmussen U, Schjerling P, Qvortrup K et al. GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients. European Journal of Endocrinology. 2010 Dec;163(6):853-62. https://doi.org/10.1530/EJE-10-0818

Author

Doessing, Simon ; Holm, Lars ; Heinemeier, Katja M ; Feldt-Rasmussen, Ulla ; Schjerling, Peter ; Qvortrup, Klaus ; Larsen, Jytte O ; Nielsen, Rie H ; Flyvbjerg, Allan ; Kjaer, Michael. / GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients. In: European Journal of Endocrinology. 2010 ; Vol. 163, No. 6. pp. 853-62.

Bibtex

@article{8269fc6d9b2b430f974edc315d2bbe22,
title = "GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients",
abstract = "Disproportionate growth of musculoskeletal tissue is a major cause of morbidity in both acromegalic (ACRO) and GH-deficient (GHD) patients. GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1.",
keywords = "Adult, Collagen, Collagen Type I, Collagen Type III, Human Growth Hormone, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Male, Microscopy, Electron, Transmission, Middle Aged, Muscle, Skeletal, RNA, Messenger, Tendons",
author = "Simon Doessing and Lars Holm and Heinemeier, {Katja M} and Ulla Feldt-Rasmussen and Peter Schjerling and Klaus Qvortrup and Larsen, {Jytte O} and Nielsen, {Rie H} and Allan Flyvbjerg and Michael Kjaer",
year = "2010",
month = dec,
doi = "10.1530/EJE-10-0818",
language = "English",
volume = "163",
pages = "853--62",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",
number = "6",

}

RIS

TY - JOUR

T1 - GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients

AU - Doessing, Simon

AU - Holm, Lars

AU - Heinemeier, Katja M

AU - Feldt-Rasmussen, Ulla

AU - Schjerling, Peter

AU - Qvortrup, Klaus

AU - Larsen, Jytte O

AU - Nielsen, Rie H

AU - Flyvbjerg, Allan

AU - Kjaer, Michael

PY - 2010/12

Y1 - 2010/12

N2 - Disproportionate growth of musculoskeletal tissue is a major cause of morbidity in both acromegalic (ACRO) and GH-deficient (GHD) patients. GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1.

AB - Disproportionate growth of musculoskeletal tissue is a major cause of morbidity in both acromegalic (ACRO) and GH-deficient (GHD) patients. GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1.

KW - Adult

KW - Collagen

KW - Collagen Type I

KW - Collagen Type III

KW - Human Growth Hormone

KW - Humans

KW - Insulin-Like Growth Factor Binding Protein 3

KW - Insulin-Like Growth Factor I

KW - Male

KW - Microscopy, Electron, Transmission

KW - Middle Aged

KW - Muscle, Skeletal

KW - RNA, Messenger

KW - Tendons

U2 - 10.1530/EJE-10-0818

DO - 10.1530/EJE-10-0818

M3 - Journal article

C2 - 20858702

VL - 163

SP - 853

EP - 862

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 6

ER -

ID: 32321075