From excitability to oscillations: A case study in vasomotion

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

From excitability to oscillations : A case study in vasomotion. / Postnov, D. E.; Neganova, A. Y.; Jacobsen, J. C. B.; von Holstein-Rathlou, Niels-Henrik; Sosnovtseva, Olga.

In: European Physical Journal. Special Topics, Vol. 222, No. 10, 10.2013, p. 2667-2676.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Postnov, DE, Neganova, AY, Jacobsen, JCB, von Holstein-Rathlou, N-H & Sosnovtseva, O 2013, 'From excitability to oscillations: A case study in vasomotion', European Physical Journal. Special Topics, vol. 222, no. 10, pp. 2667-2676. https://doi.org/10.1140/epjst/e2013-02046-3

APA

Postnov, D. E., Neganova, A. Y., Jacobsen, J. C. B., von Holstein-Rathlou, N-H., & Sosnovtseva, O. (2013). From excitability to oscillations: A case study in vasomotion. European Physical Journal. Special Topics, 222(10), 2667-2676. https://doi.org/10.1140/epjst/e2013-02046-3

Vancouver

Postnov DE, Neganova AY, Jacobsen JCB, von Holstein-Rathlou N-H, Sosnovtseva O. From excitability to oscillations: A case study in vasomotion. European Physical Journal. Special Topics. 2013 Oct;222(10):2667-2676. https://doi.org/10.1140/epjst/e2013-02046-3

Author

Postnov, D. E. ; Neganova, A. Y. ; Jacobsen, J. C. B. ; von Holstein-Rathlou, Niels-Henrik ; Sosnovtseva, Olga. / From excitability to oscillations : A case study in vasomotion. In: European Physical Journal. Special Topics. 2013 ; Vol. 222, No. 10. pp. 2667-2676.

Bibtex

@article{938e685d4aa4422f8526070488a7ee91,
title = "From excitability to oscillations: A case study in vasomotion",
abstract = "One consequence of cell-to-cell communication is the appearance of synchronized behavior, where many cells cooperate to generate new dynamical patterns. We present a simple functional model of vasomotion based on the concept of a two-mode oscillator with dual interactions: via relatively slow diffusive coupling that gives rise to wave dynamics and via fast changes in membrane potential that propagate almost instantly over significant distances. The model reproduces the basic calcium dynamics of the vascular smooth muscle cell: calcium waves which upon increased activity of cGMP-sensitive calcium-dependent chloride channels in the plasma membrane may synchronize into whole-cell oscillations which subsequently may spread across a large population of cells. We show how heterogeneity of the system can induce new patterns.",
author = "Postnov, {D. E.} and Neganova, {A. Y.} and Jacobsen, {J. C. B.} and {von Holstein-Rathlou}, Niels-Henrik and Olga Sosnovtseva",
year = "2013",
month = oct,
doi = "10.1140/epjst/e2013-02046-3",
language = "English",
volume = "222",
pages = "2667--2676",
journal = "European Physical Journal. Special Topics",
issn = "1951-6355",
publisher = "Springer",
number = "10",

}

RIS

TY - JOUR

T1 - From excitability to oscillations

T2 - A case study in vasomotion

AU - Postnov, D. E.

AU - Neganova, A. Y.

AU - Jacobsen, J. C. B.

AU - von Holstein-Rathlou, Niels-Henrik

AU - Sosnovtseva, Olga

PY - 2013/10

Y1 - 2013/10

N2 - One consequence of cell-to-cell communication is the appearance of synchronized behavior, where many cells cooperate to generate new dynamical patterns. We present a simple functional model of vasomotion based on the concept of a two-mode oscillator with dual interactions: via relatively slow diffusive coupling that gives rise to wave dynamics and via fast changes in membrane potential that propagate almost instantly over significant distances. The model reproduces the basic calcium dynamics of the vascular smooth muscle cell: calcium waves which upon increased activity of cGMP-sensitive calcium-dependent chloride channels in the plasma membrane may synchronize into whole-cell oscillations which subsequently may spread across a large population of cells. We show how heterogeneity of the system can induce new patterns.

AB - One consequence of cell-to-cell communication is the appearance of synchronized behavior, where many cells cooperate to generate new dynamical patterns. We present a simple functional model of vasomotion based on the concept of a two-mode oscillator with dual interactions: via relatively slow diffusive coupling that gives rise to wave dynamics and via fast changes in membrane potential that propagate almost instantly over significant distances. The model reproduces the basic calcium dynamics of the vascular smooth muscle cell: calcium waves which upon increased activity of cGMP-sensitive calcium-dependent chloride channels in the plasma membrane may synchronize into whole-cell oscillations which subsequently may spread across a large population of cells. We show how heterogeneity of the system can induce new patterns.

U2 - 10.1140/epjst/e2013-02046-3

DO - 10.1140/epjst/e2013-02046-3

M3 - Journal article

VL - 222

SP - 2667

EP - 2676

JO - European Physical Journal. Special Topics

JF - European Physical Journal. Special Topics

SN - 1951-6355

IS - 10

ER -

ID: 107266106