Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance
Research output: Contribution to journal › Journal article › Research › peer-review
Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P
| Original language | English |
|---|---|
| Journal | Clinical Physiology and Functional Imaging |
| Volume | 30 |
| Issue number | 3 |
| Pages (from-to) | 169-74 |
| Number of pages | 6 |
| ISSN | 1475-0961 |
| DOIs | |
| Publication status | Published - 1 May 2010 |
- Child, Child, Preschool, Chromium Radioisotopes, Edetic Acid, Female, Glomerular Filtration Rate, Humans, Infant, Infant, Newborn, Kidney, Kidney Diseases, Male, Metabolic Clearance Rate, Radioisotope Renography, Radiopharmaceuticals, Reproducibility of Results, Sensitivity and Specificity, Technetium Tc 99m Pentetate
Research areas
ID: 34277311