C-type natriuretic-derived peptides as biomarkers in human disease
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C-type natriuretic-derived peptides as biomarkers in human disease. / Lippert, Solvej Kølvraa; Goetze, Jens Peter.
In: Biomarkers in Medicine, Vol. 4, No. 4, 01.08.2010, p. 631-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - C-type natriuretic-derived peptides as biomarkers in human disease
AU - Lippert, Solvej Kølvraa
AU - Goetze, Jens Peter
PY - 2010/8/1
Y1 - 2010/8/1
N2 - The natriuretic peptide system comprises three structurally related peptides: atrial natriuretic peptide, B-type natriuretic peptide and C-type natriuretic peptide. In circulation, they play an important endocrine role in the regulation of cardiovascular homeostasis by maintaining blood pressure and extracellular fluid volume. Atrial natriuretic peptide and B-type natriuretic peptide have gained considerable diagnostic interest as biomarkers in cardiovascular disease. By contrast, C-type natriuretic peptide has not yet been ascribed a role in human diagnostics. This perspective aims at recapitulating the present biochemical and clinical issues concerning C-type natriuretic peptide measurement in plasma as a potential biomarker.
AB - The natriuretic peptide system comprises three structurally related peptides: atrial natriuretic peptide, B-type natriuretic peptide and C-type natriuretic peptide. In circulation, they play an important endocrine role in the regulation of cardiovascular homeostasis by maintaining blood pressure and extracellular fluid volume. Atrial natriuretic peptide and B-type natriuretic peptide have gained considerable diagnostic interest as biomarkers in cardiovascular disease. By contrast, C-type natriuretic peptide has not yet been ascribed a role in human diagnostics. This perspective aims at recapitulating the present biochemical and clinical issues concerning C-type natriuretic peptide measurement in plasma as a potential biomarker.
U2 - http://dx.doi.org/10.2217/bmm.10.67
DO - http://dx.doi.org/10.2217/bmm.10.67
M3 - Journal article
VL - 4
SP - 631
EP - 639
JO - Biomarkers in Medicine
JF - Biomarkers in Medicine
SN - 1752-0363
IS - 4
ER -
ID: 34132113