Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice
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Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice. / Gothelf, A; Hojman, P; Gehl, Julie.
In: Gene Therapy (Basingstoke), Vol. 17, No. 9, 01.09.2010, p. 1077-84.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice
AU - Gothelf, A
AU - Hojman, P
AU - Gehl, Julie
PY - 2010/9/1
Y1 - 2010/9/1
N2 - Gene electrotransfer refers to gene transfection by electroporation and is an effective non-viral method for delivering naked DNA into cells and tissues. This study presents data from gene electrotransfer with erythropoietin (EPO) to mouse skin. Nine-week-old female NMRI mice received one, two or three intradermal injections of 50 microg EPO plasmid and were subsequently electroporated. With plate electrodes and 100 microg of EPO, a significant increase in hemoglobin (P
AB - Gene electrotransfer refers to gene transfection by electroporation and is an effective non-viral method for delivering naked DNA into cells and tissues. This study presents data from gene electrotransfer with erythropoietin (EPO) to mouse skin. Nine-week-old female NMRI mice received one, two or three intradermal injections of 50 microg EPO plasmid and were subsequently electroporated. With plate electrodes and 100 microg of EPO, a significant increase in hemoglobin (P
U2 - http://dx.doi.org/10.1038/gt.2010.46
DO - http://dx.doi.org/10.1038/gt.2010.46
M3 - Journal article
VL - 17
SP - 1077
EP - 1084
JO - Gene Therapy
JF - Gene Therapy
SN - 0969-7128
IS - 9
ER -
ID: 34143397