The paradox of systemic vasodilatation and sympathetic nervous stimulation in space

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The paradox of systemic vasodilatation and sympathetic nervous stimulation in space. / Norsk, Peter; Christensen, Niels Juel.

In: Respiratory Physiology & Neurobiology, Vol. 169 Suppl 1, 2009, p. S26-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Norsk, P & Christensen, NJ 2009, 'The paradox of systemic vasodilatation and sympathetic nervous stimulation in space', Respiratory Physiology & Neurobiology, vol. 169 Suppl 1, pp. S26-9. https://doi.org/10.1016/j.resp.2009.07.020

APA

Norsk, P., & Christensen, N. J. (2009). The paradox of systemic vasodilatation and sympathetic nervous stimulation in space. Respiratory Physiology & Neurobiology, 169 Suppl 1, S26-9. https://doi.org/10.1016/j.resp.2009.07.020

Vancouver

Norsk P, Christensen NJ. The paradox of systemic vasodilatation and sympathetic nervous stimulation in space. Respiratory Physiology & Neurobiology. 2009;169 Suppl 1:S26-9. https://doi.org/10.1016/j.resp.2009.07.020

Author

Norsk, Peter ; Christensen, Niels Juel. / The paradox of systemic vasodilatation and sympathetic nervous stimulation in space. In: Respiratory Physiology & Neurobiology. 2009 ; Vol. 169 Suppl 1. pp. S26-9.

Bibtex

@article{ad6293d035ac11df8ed1000ea68e967b,
title = "The paradox of systemic vasodilatation and sympathetic nervous stimulation in space",
abstract = "Cardiac output is increased by some 18% by weightlessness during the initial week of spaceflight compared to upright standing or sitting on the ground and more so during the initial days of flight than at the end. In addition, mean 24-h diastolic, but not systolic pressure, is significantly decreased by 5mmHg. This is in accordance with observations that very acute weightlessness during parabolic airplane flights and a week of weightlessness in space leads to a decrease in systemic vascular resistance. That the arterial resistance vessels are dilated in space is in contrast to the augmented sympathetic nervous activity and decreased urine production, which have consistently been observed in astronauts in space. These contrasting observations require further investigation.",
author = "Peter Norsk and Christensen, {Niels Juel}",
note = "Keywords: Adaptation, Physiological; Bed Rest; Blood Pressure; Cardiac Output; Humans; Peptides; Space Flight; Sympathetic Nervous System; Vasodilation; Weightlessness",
year = "2009",
doi = "10.1016/j.resp.2009.07.020",
language = "English",
volume = "169 Suppl 1",
pages = "S26--9",
journal = "Respiratory Physiology & Neurobiology",
issn = "1569-9048",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The paradox of systemic vasodilatation and sympathetic nervous stimulation in space

AU - Norsk, Peter

AU - Christensen, Niels Juel

N1 - Keywords: Adaptation, Physiological; Bed Rest; Blood Pressure; Cardiac Output; Humans; Peptides; Space Flight; Sympathetic Nervous System; Vasodilation; Weightlessness

PY - 2009

Y1 - 2009

N2 - Cardiac output is increased by some 18% by weightlessness during the initial week of spaceflight compared to upright standing or sitting on the ground and more so during the initial days of flight than at the end. In addition, mean 24-h diastolic, but not systolic pressure, is significantly decreased by 5mmHg. This is in accordance with observations that very acute weightlessness during parabolic airplane flights and a week of weightlessness in space leads to a decrease in systemic vascular resistance. That the arterial resistance vessels are dilated in space is in contrast to the augmented sympathetic nervous activity and decreased urine production, which have consistently been observed in astronauts in space. These contrasting observations require further investigation.

AB - Cardiac output is increased by some 18% by weightlessness during the initial week of spaceflight compared to upright standing or sitting on the ground and more so during the initial days of flight than at the end. In addition, mean 24-h diastolic, but not systolic pressure, is significantly decreased by 5mmHg. This is in accordance with observations that very acute weightlessness during parabolic airplane flights and a week of weightlessness in space leads to a decrease in systemic vascular resistance. That the arterial resistance vessels are dilated in space is in contrast to the augmented sympathetic nervous activity and decreased urine production, which have consistently been observed in astronauts in space. These contrasting observations require further investigation.

U2 - 10.1016/j.resp.2009.07.020

DO - 10.1016/j.resp.2009.07.020

M3 - Journal article

C2 - 19651245

VL - 169 Suppl 1

SP - S26-9

JO - Respiratory Physiology & Neurobiology

JF - Respiratory Physiology & Neurobiology

SN - 1569-9048

ER -

ID: 18764811