The immunological network: Novel approaches to the treatment of Crohn's disease
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The immunological network : Novel approaches to the treatment of Crohn's disease. / Davidsen, B.; Nielsen, O. H.; Vainer, B.; Kirman, I.
In: Expert Opinion on Investigational Drugs, Vol. 5, No. 5, 01.01.1996, p. 555-564.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - The immunological network
T2 - Novel approaches to the treatment of Crohn's disease
AU - Davidsen, B.
AU - Nielsen, O. H.
AU - Vainer, B.
AU - Kirman, I.
PY - 1996/1/1
Y1 - 1996/1/1
N2 - This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.
AB - This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.
KW - Antibodies
KW - Crohn's disease
KW - Cytokines
KW - Disease modulation
KW - Immunology
KW - Immunomodulation
KW - Inflammation
KW - Intestinal mucosa
KW - Pharmacotherapeutics
UR - http://www.scopus.com/inward/record.url?scp=0029994839&partnerID=8YFLogxK
M3 - Review
AN - SCOPUS:0029994839
VL - 5
SP - 555
EP - 564
JO - Current Opinion in Investigational Drugs
JF - Current Opinion in Investigational Drugs
SN - 1354-3784
IS - 5
ER -
ID: 218718880