The c-erb-A protein is a high-affinity receptor for thyroid hormone.
Research output: Contribution to journal › Journal article › Research › peer-review
Hormone binding and localization of the c-erb-A protein suggest that it is a receptor for thyroid hormone, a nuclear protein that binds to DNA and activates transcription. In contrast, the product of the viral oncogene v-erb-A is defective in binding the hormone but is still located in the nucleus.
| Original language | English |
|---|---|
| Journal | Nature |
| Volume | 324 |
| Issue number | 6098 |
| Pages (from-to) | 635-40 |
| Number of pages | 5 |
| ISSN | 0028-0836 |
| DOIs | |
| Publication status | Published - 1987 |
Bibliographical note
Keywords: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA; Genes; Humans; Proto-Oncogene Proteins; Proto-Oncogenes; Receptors, Thyroid Hormone; Retroviridae; Triiodothyronine
ID: 5070304