The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population
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The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population. / Husemoen, Lise Lotte N; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, Torben; Pedersen, Oluf; Linneberg, Allan.
In: P L o S One, Vol. 5, No. 8, 01.01.2010, p. e11735.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population
AU - Husemoen, Lise Lotte N
AU - Jørgensen, Torben
AU - Borch-Johnsen, Knut
AU - Hansen, Torben
AU - Pedersen, Oluf
AU - Linneberg, Allan
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Epidemiological studies have shown a J- or U-shaped relation between alcohol and type 2 diabetes and coronary heart disease (CHD). The underlying mechanisms are not clear. The aim was to examine the association between alcohol intake and diabetes and intermediate CHD risk factors in relation to selected ADH and ALDH gene variants.
AB - Epidemiological studies have shown a J- or U-shaped relation between alcohol and type 2 diabetes and coronary heart disease (CHD). The underlying mechanisms are not clear. The aim was to examine the association between alcohol intake and diabetes and intermediate CHD risk factors in relation to selected ADH and ALDH gene variants.
KW - Adult
KW - Aged
KW - Alcohol Dehydrogenase
KW - Alcohol Drinking
KW - Alcohols
KW - Aldehyde Dehydrogenase
KW - Coronary Disease
KW - Diabetes Mellitus
KW - European Continental Ancestry Group
KW - Female
KW - Genetic Predisposition to Disease
KW - Genetic Variation
KW - Humans
KW - Male
KW - Middle Aged
KW - Risk Factors
U2 - 10.1371/journal.pone.0011735
DO - 10.1371/journal.pone.0011735
M3 - Journal article
C2 - 20700531
VL - 5
SP - e11735
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 8
ER -
ID: 33505365