Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure. / Gabrielsen, A; Bie, P; Christensen, N J; Frandsen, E; Galatius, S; Pump, B; Sørensen, V B; Kastrup, J; Norsk, P.

In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 62, No. 4, 01.01.2002, p. 245-54.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gabrielsen, A, Bie, P, Christensen, NJ, Frandsen, E, Galatius, S, Pump, B, Sørensen, VB, Kastrup, J & Norsk, P 2002, 'Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 62, no. 4, pp. 245-54.

APA

Gabrielsen, A., Bie, P., Christensen, N. J., Frandsen, E., Galatius, S., Pump, B., Sørensen, V. B., Kastrup, J., & Norsk, P. (2002). Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure. Scandinavian Journal of Clinical & Laboratory Investigation, 62(4), 245-54.

Vancouver

Gabrielsen A, Bie P, Christensen NJ, Frandsen E, Galatius S, Pump B et al. Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure. Scandinavian Journal of Clinical & Laboratory Investigation. 2002 Jan 1;62(4):245-54.

Author

Gabrielsen, A ; Bie, P ; Christensen, N J ; Frandsen, E ; Galatius, S ; Pump, B ; Sørensen, V B ; Kastrup, J ; Norsk, P. / Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure. In: Scandinavian Journal of Clinical & Laboratory Investigation. 2002 ; Vol. 62, No. 4. pp. 245-54.

Bibtex

@article{9489a36b224c4d198aadb99c789712c1,
title = "Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure",
abstract = "We tested the hypothesis that moderate increases in endogenous angiotensin II (Ang II) concentrations, induced by withdrawal of angiotensin converting enzyme inhibition (ACE-I) in patients with compensated heart failure (HF) on chronic medical therapy, do not increase or impair control of systemic vascular resistance (SVR). SVR was determined in supine and seated positions in 12 HF patients [NYHA class II-III; ejection fraction=0.29 +/- 0.03 (mean +/- SE)] and 9 control subjects. HF patients were investigated during high (n=11; withdrawal of ACE-I treatment for 24 h) and low (n=9; sustained ACE-I therapy) endogenous plasma Ang II concentrations. Withdrawal of ACE-I therapy in HF caused moderately increased Ang II concentrations of 30 +/- 5 pg/ml compared with 12 +/- 2 pg/ml in controls (p",
keywords = "Angiotensin-Converting Enzyme Inhibitors, Baroreflex, Blood Pressure, Cardiac Output, Heart Failure, Humans, Male, Middle Aged, Posture, Substance Withdrawal Syndrome, Sympathetic Nervous System, Vascular Resistance",
author = "A Gabrielsen and P Bie and Christensen, {N J} and E Frandsen and S Galatius and B Pump and S{\o}rensen, {V B} and J Kastrup and P Norsk",
year = "2002",
month = jan,
day = "1",
language = "English",
volume = "62",
pages = "245--54",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure

AU - Gabrielsen, A

AU - Bie, P

AU - Christensen, N J

AU - Frandsen, E

AU - Galatius, S

AU - Pump, B

AU - Sørensen, V B

AU - Kastrup, J

AU - Norsk, P

PY - 2002/1/1

Y1 - 2002/1/1

N2 - We tested the hypothesis that moderate increases in endogenous angiotensin II (Ang II) concentrations, induced by withdrawal of angiotensin converting enzyme inhibition (ACE-I) in patients with compensated heart failure (HF) on chronic medical therapy, do not increase or impair control of systemic vascular resistance (SVR). SVR was determined in supine and seated positions in 12 HF patients [NYHA class II-III; ejection fraction=0.29 +/- 0.03 (mean +/- SE)] and 9 control subjects. HF patients were investigated during high (n=11; withdrawal of ACE-I treatment for 24 h) and low (n=9; sustained ACE-I therapy) endogenous plasma Ang II concentrations. Withdrawal of ACE-I therapy in HF caused moderately increased Ang II concentrations of 30 +/- 5 pg/ml compared with 12 +/- 2 pg/ml in controls (p

AB - We tested the hypothesis that moderate increases in endogenous angiotensin II (Ang II) concentrations, induced by withdrawal of angiotensin converting enzyme inhibition (ACE-I) in patients with compensated heart failure (HF) on chronic medical therapy, do not increase or impair control of systemic vascular resistance (SVR). SVR was determined in supine and seated positions in 12 HF patients [NYHA class II-III; ejection fraction=0.29 +/- 0.03 (mean +/- SE)] and 9 control subjects. HF patients were investigated during high (n=11; withdrawal of ACE-I treatment for 24 h) and low (n=9; sustained ACE-I therapy) endogenous plasma Ang II concentrations. Withdrawal of ACE-I therapy in HF caused moderately increased Ang II concentrations of 30 +/- 5 pg/ml compared with 12 +/- 2 pg/ml in controls (p

KW - Angiotensin-Converting Enzyme Inhibitors

KW - Baroreflex

KW - Blood Pressure

KW - Cardiac Output

KW - Heart Failure

KW - Humans

KW - Male

KW - Middle Aged

KW - Posture

KW - Substance Withdrawal Syndrome

KW - Sympathetic Nervous System

KW - Vascular Resistance

M3 - Journal article

C2 - 12476922

VL - 62

SP - 245

EP - 254

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 4

ER -

ID: 33967768