Skeletal Muscle: A Brief Review of Structure and Function
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Skeletal Muscle : A Brief Review of Structure and Function. / Frontera, Walter R.; Ochala, Julien.
In: Behavior Genetics, Vol. 45, No. 2, 04.03.2015, p. 183-195.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Skeletal Muscle
T2 - A Brief Review of Structure and Function
AU - Frontera, Walter R.
AU - Ochala, Julien
PY - 2015/3/4
Y1 - 2015/3/4
N2 - Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In humans, skeletal muscle comprises approximately 40 % of total body weight and contains 50–75 % of all body proteins. In general, muscle mass depends on the balance between protein synthesis and degradation and both processes are sensitive to factors such as nutritional status, hormonal balance, physical activity/exercise, and injury or disease, among others. In this review, we discuss the various domains of muscle structure and function including its cytoskeletal architecture, excitation-contraction coupling, energy metabolism, and force and power generation. We will limit the discussion to human skeletal muscle and emphasize recent scientific literature on single muscle fibers.
AB - Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In humans, skeletal muscle comprises approximately 40 % of total body weight and contains 50–75 % of all body proteins. In general, muscle mass depends on the balance between protein synthesis and degradation and both processes are sensitive to factors such as nutritional status, hormonal balance, physical activity/exercise, and injury or disease, among others. In this review, we discuss the various domains of muscle structure and function including its cytoskeletal architecture, excitation-contraction coupling, energy metabolism, and force and power generation. We will limit the discussion to human skeletal muscle and emphasize recent scientific literature on single muscle fibers.
KW - Dystrophy
KW - Exercise
KW - Force generation
KW - Metabolism
KW - Muscle actions
KW - Sarcopenia
UR - http://www.scopus.com/inward/record.url?scp=84941651873&partnerID=8YFLogxK
U2 - 10.1007/s00223-014-9915-y
DO - 10.1007/s00223-014-9915-y
M3 - Review
C2 - 25294644
AN - SCOPUS:84941651873
VL - 45
SP - 183
EP - 195
JO - Behavior Genetics
JF - Behavior Genetics
SN - 0001-8244
IS - 2
ER -
ID: 245662890