Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans.
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans. / Yoneda, Atsuko; Couchman, John R.
In: Matrix Biology, Vol. 22, No. 1, 2003, p. 25-33.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans.
AU - Yoneda, Atsuko
AU - Couchman, John R
N1 - Keywords: Actins; Amino Acid Sequence; Animals; Cytoskeleton; Focal Adhesions; Humans; Integrins; Membrane Glycoproteins; Molecular Sequence Data; Neurites; Proteoglycans; Syndecans
PY - 2003
Y1 - 2003
N2 - Syndecans, a family of transmembrane proteoglycans, interact with numerous extracellular ligands through specific sequences in their heparan sulfate chains and have been considered to be co-receptors for matrix molecules and growth factors. In addition to their roles as co-receptors, many studies have recently suggested that signaling through core protein of syndecans can regulate cytoskeletal organization through their clustering, association with cytoskeletal structures, binding to cytoplasmic binding proteins, and intracellular phosphorylation. Here we will review current understanding of signaling through syndecans in cytoskeletal organization.
AB - Syndecans, a family of transmembrane proteoglycans, interact with numerous extracellular ligands through specific sequences in their heparan sulfate chains and have been considered to be co-receptors for matrix molecules and growth factors. In addition to their roles as co-receptors, many studies have recently suggested that signaling through core protein of syndecans can regulate cytoskeletal organization through their clustering, association with cytoskeletal structures, binding to cytoplasmic binding proteins, and intracellular phosphorylation. Here we will review current understanding of signaling through syndecans in cytoskeletal organization.
M3 - Journal article
C2 - 12714039
VL - 22
SP - 25
EP - 33
JO - Matrix Biology
JF - Matrix Biology
SN - 0945-053X
IS - 1
ER -
ID: 5162655