Quantitation and gompertzian analysis of tumor growth
Research output: Contribution to journal › Journal article › Research › peer-review
Human tumor xenografts in immune-deficient animals are used to establish tumor growth curves and for studying the effect of experimental therapy on tumor growth. In this review we describe a method for making serial measurements of tumor size in the nude mouse model as well as methods used to transform the experimental data into useful growth curves. A transformed Gompertz function is used as the basis for calculating relevant parameters pertaining to tumor growth and response to therapy. The calculations are facilitated by use of a computer program which performs the necessary calculations and presents the growth data in graphic form.
Original language | English |
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Journal | Breast Cancer Research and Treatment |
Volume | 46 |
Issue number | 2-3 |
Pages (from-to) | 303-12 |
Number of pages | 9 |
ISSN | 0167-6806 |
Publication status | Published - 1998 |
Bibliographical note
Keywords: Animals; Cell Division; Data Interpretation, Statistical; Disease Models, Animal; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Transplantation, Heterologous
ID: 12870087