Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis

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Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis. / Engkilde, Kaare; Buschard, Karsten; Hansen, Axel Jacob Kornerup; Menné, Torkil; Johansen, Jeanne Duus.

In: PLoS ONE, Vol. 5, No. 5, 2010, p. e10591.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Engkilde, K, Buschard, K, Hansen, AJK, Menné, T & Johansen, JD 2010, 'Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis', PLoS ONE, vol. 5, no. 5, pp. e10591. https://doi.org/10.1371/journal.pone.0010591

APA

Engkilde, K., Buschard, K., Hansen, A. J. K., Menné, T., & Johansen, J. D. (2010). Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis. PLoS ONE, 5(5), e10591. https://doi.org/10.1371/journal.pone.0010591

Vancouver

Engkilde K, Buschard K, Hansen AJK, Menné T, Johansen JD. Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis. PLoS ONE. 2010;5(5):e10591. https://doi.org/10.1371/journal.pone.0010591

Author

Engkilde, Kaare ; Buschard, Karsten ; Hansen, Axel Jacob Kornerup ; Menné, Torkil ; Johansen, Jeanne Duus. / Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis. In: PLoS ONE. 2010 ; Vol. 5, No. 5. pp. e10591.

Bibtex

@article{5f055af0845411df928f000ea68e967b,
title = "Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis",
abstract = "Type 1 diabetes is an autoimmune disease, while allergic contact dermatitis although immune mediated, is considered an exposure driven disease that develops due to epicutaneous contact with reactive low-molecular chemicals. The objective of the present study was to experimentally study the effect of contact allergens on the development of diabetes in NOD mice. As the link between contact allergy and diabetes is yet unexplained we also examined the effect of provocation with allergens on Natural Killer T (NKT) cells, since involvement of NKT cells could suggest an innate connection between the two diseases.",
author = "Kaare Engkilde and Karsten Buschard and Hansen, {Axel Jacob Kornerup} and Torkil Menn{\'e} and Johansen, {Jeanne Duus}",
note = "e10591",
year = "2010",
doi = "10.1371/journal.pone.0010591",
language = "English",
volume = "5",
pages = "e10591",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "5",

}

RIS

TY - JOUR

T1 - Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis

AU - Engkilde, Kaare

AU - Buschard, Karsten

AU - Hansen, Axel Jacob Kornerup

AU - Menné, Torkil

AU - Johansen, Jeanne Duus

N1 - e10591

PY - 2010

Y1 - 2010

N2 - Type 1 diabetes is an autoimmune disease, while allergic contact dermatitis although immune mediated, is considered an exposure driven disease that develops due to epicutaneous contact with reactive low-molecular chemicals. The objective of the present study was to experimentally study the effect of contact allergens on the development of diabetes in NOD mice. As the link between contact allergy and diabetes is yet unexplained we also examined the effect of provocation with allergens on Natural Killer T (NKT) cells, since involvement of NKT cells could suggest an innate connection between the two diseases.

AB - Type 1 diabetes is an autoimmune disease, while allergic contact dermatitis although immune mediated, is considered an exposure driven disease that develops due to epicutaneous contact with reactive low-molecular chemicals. The objective of the present study was to experimentally study the effect of contact allergens on the development of diabetes in NOD mice. As the link between contact allergy and diabetes is yet unexplained we also examined the effect of provocation with allergens on Natural Killer T (NKT) cells, since involvement of NKT cells could suggest an innate connection between the two diseases.

U2 - 10.1371/journal.pone.0010591

DO - 10.1371/journal.pone.0010591

M3 - Journal article

C2 - 20485668

VL - 5

SP - e10591

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 5

ER -

ID: 20601874