Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure. / Sourris, Karly C; Lyons, Jasmine G; Dougherty, Sonia L; Chand, Vibhasha; Straznicky, Nora E; Schlaich, Markus P; Grima, Mariee T; Cooper, Mark E; Kingwell, Bronwyn A; de Courten, Maximilian; Forbes, Josephine M; de Courten, Barbora.

In: Clinical chemistry and laboratory medicine : CCLM / FESCC, Vol. 52, No. 1, 23.03.2013, p. 129-138.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sourris, KC, Lyons, JG, Dougherty, SL, Chand, V, Straznicky, NE, Schlaich, MP, Grima, MT, Cooper, ME, Kingwell, BA, de Courten, M, Forbes, JM & de Courten, B 2013, 'Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure', Clinical chemistry and laboratory medicine : CCLM / FESCC, vol. 52, no. 1, pp. 129-138. https://doi.org/10.1515/cclm-2012-0850

APA

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., de Courten, M., Forbes, J. M., & de Courten, B. (2013). Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure. Clinical chemistry and laboratory medicine : CCLM / FESCC, 52(1), 129-138. https://doi.org/10.1515/cclm-2012-0850

Vancouver

Sourris KC, Lyons JG, Dougherty SL, Chand V, Straznicky NE, Schlaich MP et al. Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure. Clinical chemistry and laboratory medicine : CCLM / FESCC. 2013 Mar 23;52(1):129-138. https://doi.org/10.1515/cclm-2012-0850

Author

Sourris, Karly C ; Lyons, Jasmine G ; Dougherty, Sonia L ; Chand, Vibhasha ; Straznicky, Nora E ; Schlaich, Markus P ; Grima, Mariee T ; Cooper, Mark E ; Kingwell, Bronwyn A ; de Courten, Maximilian ; Forbes, Josephine M ; de Courten, Barbora. / Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure. In: Clinical chemistry and laboratory medicine : CCLM / FESCC. 2013 ; Vol. 52, No. 1. pp. 129-138.

Bibtex

@article{005da697313440898556ad30113b225c,
title = "Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure",
abstract = "Abstract Background: High levels of circulating advanced glycation end products (AGEs) can initiate chronic low-grade activation of the immune system (CLAIS) with each of these factors independently associated with cardiovascular (CV) morbidity and mortality. Therefore, our objective was to characterize the relationship between serum AGEs, CLAIS and other risk factors for CV disease in normotensive non-diabetic individuals. Methods: We measured body mass index (BMI), waist-to-hip ratio (WHR), blood pressure, lipid and glucose profile in 44 non-diabetic volunteers (17 female, 27 males). Carboxymethyl-lysine (CML) was measured by ELISA as a marker for circulating AGEs and NF-κB p65 activity as an inflammatory marker by DNA-binding in peripheral blood mononuclear cells lysates (PBMC). Results: Plasma CML concentrations were related to diastolic blood pressure (r=-0.51, p",
author = "Sourris, {Karly C} and Lyons, {Jasmine G} and Dougherty, {Sonia L} and Vibhasha Chand and Straznicky, {Nora E} and Schlaich, {Markus P} and Grima, {Mariee T} and Cooper, {Mark E} and Kingwell, {Bronwyn A} and {de Courten}, Maximilian and Forbes, {Josephine M} and {de Courten}, Barbora",
year = "2013",
month = mar,
day = "23",
doi = "10.1515/cclm-2012-0850",
language = "English",
volume = "52",
pages = "129--138",
journal = "Clinical Chemistry and Laboratory Medicine",
issn = "1434-6621",
publisher = "Walterde Gruyter GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

AU - Sourris, Karly C

AU - Lyons, Jasmine G

AU - Dougherty, Sonia L

AU - Chand, Vibhasha

AU - Straznicky, Nora E

AU - Schlaich, Markus P

AU - Grima, Mariee T

AU - Cooper, Mark E

AU - Kingwell, Bronwyn A

AU - de Courten, Maximilian

AU - Forbes, Josephine M

AU - de Courten, Barbora

PY - 2013/3/23

Y1 - 2013/3/23

N2 - Abstract Background: High levels of circulating advanced glycation end products (AGEs) can initiate chronic low-grade activation of the immune system (CLAIS) with each of these factors independently associated with cardiovascular (CV) morbidity and mortality. Therefore, our objective was to characterize the relationship between serum AGEs, CLAIS and other risk factors for CV disease in normotensive non-diabetic individuals. Methods: We measured body mass index (BMI), waist-to-hip ratio (WHR), blood pressure, lipid and glucose profile in 44 non-diabetic volunteers (17 female, 27 males). Carboxymethyl-lysine (CML) was measured by ELISA as a marker for circulating AGEs and NF-κB p65 activity as an inflammatory marker by DNA-binding in peripheral blood mononuclear cells lysates (PBMC). Results: Plasma CML concentrations were related to diastolic blood pressure (r=-0.51, p

AB - Abstract Background: High levels of circulating advanced glycation end products (AGEs) can initiate chronic low-grade activation of the immune system (CLAIS) with each of these factors independently associated with cardiovascular (CV) morbidity and mortality. Therefore, our objective was to characterize the relationship between serum AGEs, CLAIS and other risk factors for CV disease in normotensive non-diabetic individuals. Methods: We measured body mass index (BMI), waist-to-hip ratio (WHR), blood pressure, lipid and glucose profile in 44 non-diabetic volunteers (17 female, 27 males). Carboxymethyl-lysine (CML) was measured by ELISA as a marker for circulating AGEs and NF-κB p65 activity as an inflammatory marker by DNA-binding in peripheral blood mononuclear cells lysates (PBMC). Results: Plasma CML concentrations were related to diastolic blood pressure (r=-0.51, p

U2 - 10.1515/cclm-2012-0850

DO - 10.1515/cclm-2012-0850

M3 - Journal article

C2 - 23525877

VL - 52

SP - 129

EP - 138

JO - Clinical Chemistry and Laboratory Medicine

JF - Clinical Chemistry and Laboratory Medicine

SN - 1434-6621

IS - 1

ER -

ID: 46066727