The basic biochemistry of de novo lipogenesis and the current understanding of fat formation from carbohydrates in humans are reviewed. The suggestion is made that ingestion of carbohydrates in excess of the caloric needs necessarily results in de novo lipogenesis since the glycogen stores are already full. Under these circumstances a formation per day of 15-20 g palmitate from carbohydrates has been reported in the liver and a similar amount in the peripheral tissues.
Udgivelsesdato: 2003-Apr-7