Myeloid sarcoma developing in pre-existing pyoderma gangrenosum
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Myeloid sarcoma developing in pre-existing pyoderma gangrenosum. / Kristensen, Ida Bruun; Møller, Hanne; Kjaerskov, Mette Wanscher; Yderstraede, Knud; Møller, Michael Boe; Bergmann, Olav J.
In: Acta Dermato Venereologica, Vol. 89, No. 2, 2009, p. 175-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Myeloid sarcoma developing in pre-existing pyoderma gangrenosum
AU - Kristensen, Ida Bruun
AU - Møller, Hanne
AU - Kjaerskov, Mette Wanscher
AU - Yderstraede, Knud
AU - Møller, Michael Boe
AU - Bergmann, Olav J
N1 - Keywords: Cell Transformation, Neoplastic; Female; Humans; Leg Ulcer; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Pyoderma Gangrenosum; Sarcoma, Myeloid; Skin Neoplasms
PY - 2009
Y1 - 2009
N2 - We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.
AB - We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.
U2 - 10.2340/00015555-0590
DO - 10.2340/00015555-0590
M3 - Journal article
C2 - 19326005
VL - 89
SP - 175
EP - 177
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 2
ER -
ID: 18764158