Management of cutaneous metastases using electrochemotherapy

Research output: Contribution to journalJournal articleResearchpeer-review

  • Louise Wichmann Matthiessen
  • Richard Ling Chalmers
  • David Christopher George Sainsbury
  • Sivakumar Veeramani
  • Gareth Kessell
  • Alison Claire Humphreys
  • Jane Elisabeth Bond
  • Tobian Muir
  • Gehl, Julie
Cutaneous metastases may cause considerable discomfort as a consequence of ulceration, oozing, bleeding and pain. Electrochemotherapy has proven to be highly effective in the treatment of cutaneous metastases. Electrochemotherapy utilises pulses of electricity to increase the permeability of the cell membrane and thereby augment the effect of chemotherapy. For the drug bleomycin, the effect is enhanced several hundred-fold, enabling once-only treatment. The primary endpoint of this study is to evaluate the efficacy of electrochemotherapy as a palliative treatment.
Original languageEnglish
JournalActa Oncologica
Volume50
Issue number5
Pages (from-to)621-9
Number of pages9
ISSN0284-186X
DOIs
Publication statusPublished - 2011

ID: 40153336