Localization of a new serine protease, ingobsin, in goblet cells in rat, pig and man
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Localization of a new serine protease, ingobsin, in goblet cells in rat, pig and man. / Poulsen, Steen Seier; Nexø, Ebba.
In: The Histochemical Journal, Vol. 17, No. 4, 04.1985, p. 487-92.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Localization of a new serine protease, ingobsin, in goblet cells in rat, pig and man
AU - Poulsen, Steen Seier
AU - Nexø, Ebba
PY - 1985/4
Y1 - 1985/4
N2 - A serine protease, ingobsin, that cleaves Lys-x and Arg-x, has been purified from rat duodenal tissue. By immunohistochemical methods, the enzyme was localized in goblet cells in the small intestine of rat, pig, and man. The immunoreactive cells were most numerous in the proximal part of the intestine. In the electron microscope, the immunoreaction was localized mainly to the rough endoplasmic reticulum of the goblet cells and to the secretion being extruded from the cells.
AB - A serine protease, ingobsin, that cleaves Lys-x and Arg-x, has been purified from rat duodenal tissue. By immunohistochemical methods, the enzyme was localized in goblet cells in the small intestine of rat, pig, and man. The immunoreactive cells were most numerous in the proximal part of the intestine. In the electron microscope, the immunoreaction was localized mainly to the rough endoplasmic reticulum of the goblet cells and to the secretion being extruded from the cells.
KW - Animals
KW - Duodenum
KW - Endopeptidases
KW - Endoplasmic Reticulum
KW - Humans
KW - Immunoenzyme Techniques
KW - Intestinal Mucosa
KW - Male
KW - Microscopy, Electron
KW - Rats
KW - Serine Endopeptidases
KW - Swine
M3 - Journal article
C2 - 3900001
VL - 17
SP - 487
EP - 492
JO - The Histochemical Journal
JF - The Histochemical Journal
SN - 0018-2214
IS - 4
ER -
ID: 47489071