Improved pancreatic beta-cell function in type 2 diabetic patients after lifestyle-induced weight loss is related to glucose-dependent insulinotropic polypeptide
Research output: Contribution to journal › Journal article › Research › peer-review
Restoration of insulin secretion is critical for the treatment of type 2 diabetes. Exercise and diet can alter glucose-induced insulin responses, but whether this is due to changes in beta-cell function per se is not clear. The mechanisms by which lifestyle intervention may modify insulin secretion in type 2 diabetes have also not been examined but may involve the incretin axis.
| Original language | English |
|---|---|
| Journal | Diabetes Care |
| Volume | 33 |
| Issue number | 7 |
| Pages (from-to) | 1561-6 |
| Number of pages | 6 |
| ISSN | 0149-5992 |
| DOIs | |
| Publication status | Published - Jul 2010 |
- Aged, Blood Glucose, Diabetes Mellitus, Type 2, Diet, Reducing, Exercise, Female, Gastric Inhibitory Polypeptide, Glucose Clamp Technique, Humans, Hyperinsulinism, Insulin, Insulin Resistance, Insulin-Secreting Cells, Life Style, Male, Middle Aged, Obesity, Physical Fitness, Weight Loss
Research areas
ID: 50218285