Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance
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Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance. / Gutte, Henrik; Møller, Michael L; Pfeifer, Andreas K; Thorup, Jørgen Mogens; Borgwardt, Line; Borgwardt, Lise; Kristoffersen, Ulrik S; Kjaer, Andreas.
In: Clinical Physiology and Functional Imaging, Vol. 30, No. 3, 01.05.2010, p. 169-74.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance
AU - Gutte, Henrik
AU - Møller, Michael L
AU - Pfeifer, Andreas K
AU - Thorup, Jørgen Mogens
AU - Borgwardt, Line
AU - Borgwardt, Lise
AU - Kristoffersen, Ulrik S
AU - Kjaer, Andreas
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P
AB - Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P
KW - Child
KW - Child, Preschool
KW - Chromium Radioisotopes
KW - Edetic Acid
KW - Female
KW - Glomerular Filtration Rate
KW - Humans
KW - Infant
KW - Infant, Newborn
KW - Kidney
KW - Kidney Diseases
KW - Male
KW - Metabolic Clearance Rate
KW - Radioisotope Renography
KW - Radiopharmaceuticals
KW - Reproducibility of Results
KW - Sensitivity and Specificity
KW - Technetium Tc 99m Pentetate
U2 - 10.1111/j.1475-097X.2009.00910.x
DO - 10.1111/j.1475-097X.2009.00910.x
M3 - Journal article
C2 - 20214666
VL - 30
SP - 169
EP - 174
JO - Clinical Physiology and Functional Imaging
JF - Clinical Physiology and Functional Imaging
SN - 1475-0961
IS - 3
ER -
ID: 34277311