TY - JOUR

T1 - Echocardiography-derived total atrial conduction time (PA-TDI duration)

T2 - risk stratification and guidance in atrial fibrillation management

AU - Müller, Patrick

AU - Weijs, Bob

AU - Bemelmans, Nadine M.A.A.

AU - Mügge, Andreas

AU - Eckardt, Lars

AU - Crijns, Harry J.G.M.

AU - Bax, Jeroen J.

AU - Linz, Dominik

AU - den Uijl, Dennis W.

N1 - +

PY - 2021

Y1 - 2021

N2 - Atrial fibrillation (AF) is a major cause of cardiovascular morbidity and mortality. To early detect and to avoid AF-related complications, several cardiac imaging modalities and approaches aim to quantify the severity of the underlying atrial cardiomyopathy (i.e., the extent of atrial remodeling). However, most established cardiac imaging modalities just incorporate single components of atrial remodeling and do not reflect the complete multifactorial process, which may contribute to their limited predictive value. Echocardiography-derived PA-TDI duration is a sophisticated echocardiographic parameter to assess total atrial conduction time and directly reflects both electrical and structural changes to the atria. Therefore, PA-TDI duration provides a more comprehensive quantification of the extent of atrial remodeling than other imaging modalities. In this article we review the role of PA-TDI duration as a marker of atrial remodeling and summarize the available data on PA-TDI duration to identify patients at risk for AF, as well as to guide AF management. Moreover, we discuss how to assess PA-TDI duration and provide recommendations on the implementation of PA-TDI duration into routine clinical care. Graphic abstract: [Figure not available: see fulltext.]

AB - Atrial fibrillation (AF) is a major cause of cardiovascular morbidity and mortality. To early detect and to avoid AF-related complications, several cardiac imaging modalities and approaches aim to quantify the severity of the underlying atrial cardiomyopathy (i.e., the extent of atrial remodeling). However, most established cardiac imaging modalities just incorporate single components of atrial remodeling and do not reflect the complete multifactorial process, which may contribute to their limited predictive value. Echocardiography-derived PA-TDI duration is a sophisticated echocardiographic parameter to assess total atrial conduction time and directly reflects both electrical and structural changes to the atria. Therefore, PA-TDI duration provides a more comprehensive quantification of the extent of atrial remodeling than other imaging modalities. In this article we review the role of PA-TDI duration as a marker of atrial remodeling and summarize the available data on PA-TDI duration to identify patients at risk for AF, as well as to guide AF management. Moreover, we discuss how to assess PA-TDI duration and provide recommendations on the implementation of PA-TDI duration into routine clinical care. Graphic abstract: [Figure not available: see fulltext.]

KW - Atrial fibrillation

KW - PA-TDI duration

KW - Total atrial conduction time

UR - http://www.scopus.com/inward/record.url?scp=85113742701&partnerID=8YFLogxK

U2 - 10.1007/s00392-021-01917-9

DO - 10.1007/s00392-021-01917-9

M3 - Review

C2 - 34453577

AN - SCOPUS:85113742701

VL - 110

SP - 1734

EP - 1742

JO - Clinical Research in Cardiology

JF - Clinical Research in Cardiology

SN - 1861-0684

IS - 11

ER -