Eccentric exercise: acute and chronic effects on healthy and diseased tendons
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Eccentric exercise : acute and chronic effects on healthy and diseased tendons. / Kjaer, Michael; Heinemeier, Katja Maria.
In: Journal of Applied Physiology, Vol. 116, No. 11, 01.06.2014, p. 1435-1438.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Eccentric exercise
T2 - acute and chronic effects on healthy and diseased tendons
AU - Kjaer, Michael
AU - Heinemeier, Katja Maria
N1 - Copyright © 2014 the American Physiological Society.
PY - 2014/6/1
Y1 - 2014/6/1
N2 - Eccentric exercise can influence tendon mechanical properties and matrix protein synthesis. mRNA for collagen and regulatory factors thereof are upregulated in animal tendons, independent of muscular contraction type, supporting the view that tendon, compared with skeletal muscle, is less sensitive to differences in type and/or amount of mechanical stimulus with regard to expression of collagen, regulatory factors for collagen, and cross-link regulators. In overused (tendinopathic) human tendon, eccentric exercise training has a beneficial effect, but the mechanism by which this is elicited is unknown, and slow concentric loading appears to have similar beneficial effects. It may be that tendinopathic regions, as long as they are subjected to a certain magnitude of load at a slow speed, independent of whether this is eccentric or concentric in nature, can reestablish their normal tendon fibril alignment and cell morphology.
AB - Eccentric exercise can influence tendon mechanical properties and matrix protein synthesis. mRNA for collagen and regulatory factors thereof are upregulated in animal tendons, independent of muscular contraction type, supporting the view that tendon, compared with skeletal muscle, is less sensitive to differences in type and/or amount of mechanical stimulus with regard to expression of collagen, regulatory factors for collagen, and cross-link regulators. In overused (tendinopathic) human tendon, eccentric exercise training has a beneficial effect, but the mechanism by which this is elicited is unknown, and slow concentric loading appears to have similar beneficial effects. It may be that tendinopathic regions, as long as they are subjected to a certain magnitude of load at a slow speed, independent of whether this is eccentric or concentric in nature, can reestablish their normal tendon fibril alignment and cell morphology.
U2 - 10.1152/japplphysiol.01044.2013
DO - 10.1152/japplphysiol.01044.2013
M3 - Journal article
C2 - 24436295
VL - 116
SP - 1435
EP - 1438
JO - Journal of Applied Physiology
JF - Journal of Applied Physiology
SN - 8750-7587
IS - 11
ER -
ID: 127352619