Dynamic light scattering imaging
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Dynamic light scattering imaging. / Postnov, Dmitry D.; Tang, Jianbo; Erdener, Sefik Evren; Kilic, Kivilcim; Boas, David A.
In: Science Advances, Vol. 6, No. 45, 4628, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Dynamic light scattering imaging
AU - Postnov, Dmitry D.
AU - Tang, Jianbo
AU - Erdener, Sefik Evren
AU - Kilic, Kivilcim
AU - Boas, David A.
PY - 2020
Y1 - 2020
N2 - We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.
AB - We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.
KW - DIFFUSE CORRELATION SPECTROSCOPY
KW - FOCAL CEREBRAL-ISCHEMIA
KW - BLOOD-FLOW
KW - SPECKLE
KW - MODEL
KW - FLOWMETRY
KW - ACCURACY
KW - BRAIN
KW - SKULL
U2 - 10.1126/sciadv.abc4628
DO - 10.1126/sciadv.abc4628
M3 - Journal article
C2 - 33158865
VL - 6
JO - Science advances
JF - Science advances
SN - 2375-2548
IS - 45
M1 - 4628
ER -
ID: 252042639