Dietary protein recommendations to support healthy muscle ageing in the 21stCentury and beyond: considerations and future directions
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Dietary protein recommendations to support healthy muscle ageing in the 21stCentury and beyond : considerations and future directions. / Morgan, Paul T.; Witard, Oliver C.; Højfeldt, Grith; Church, David D.; Breen, Leigh.
In: Proceedings of the Nutrition Society, 2024.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Dietary protein recommendations to support healthy muscle ageing in the 21stCentury and beyond
T2 - considerations and future directions
AU - Morgan, Paul T.
AU - Witard, Oliver C.
AU - Højfeldt, Grith
AU - Church, David D.
AU - Breen, Leigh
N1 - Publisher Copyright: © 2023 Cambridge University Press. All rights reserved.
PY - 2024
Y1 - 2024
N2 - This review explores the evolution of dietary protein intake requirements and recommendations, with a focus on skeletal muscle remodeling to support healthy ageing based on presentations at the 2023 Nutrition Society summer conference. In this review, we describe the role of dietary protein for metabolic health and ageing muscle, explain the origins of protein and amino acid requirements, and discuss current recommendations for dietary protein intake, which currently sits at ∼0.8g·kg·-1day-1. We also critique existing (e.g., nitrogen balance) and contemporary (e.g., indicator amino acid oxidation) methods to determine protein/amino acid intake requirements and suggest that existing methods may underestimate requirements, with more contemporary assessments indicating protein recommendations may need to be increased to >1.0g·kg·-1day-1. One example of evolution in dietary protein guidance is the transition from protein requirements to recommendations. Hence, we discuss the refinement of protein/amino acid requirements for skeletal muscle maintenance with advanced age beyond simply the dose (e.g., source, type, quality, timing, pattern, nutrient co-ingestion) and explore the efficacy and sustainability of alternative protein sources beyond animal-based proteins to facilitate skeletal muscle remodeling in older age. We conclude that, whilst a growing body of research has demonstrated that animal-free protein sources can effectively stimulate support muscle remodeling in a manner that is comparable to animal-based proteins, food systems need to sustainably provide a diversity of both plant and animal source foods, not least for their protein content but other vital nutrients. Finally, we propose some priority research directions for the field of protein nutrition and healthy ageing.
AB - This review explores the evolution of dietary protein intake requirements and recommendations, with a focus on skeletal muscle remodeling to support healthy ageing based on presentations at the 2023 Nutrition Society summer conference. In this review, we describe the role of dietary protein for metabolic health and ageing muscle, explain the origins of protein and amino acid requirements, and discuss current recommendations for dietary protein intake, which currently sits at ∼0.8g·kg·-1day-1. We also critique existing (e.g., nitrogen balance) and contemporary (e.g., indicator amino acid oxidation) methods to determine protein/amino acid intake requirements and suggest that existing methods may underestimate requirements, with more contemporary assessments indicating protein recommendations may need to be increased to >1.0g·kg·-1day-1. One example of evolution in dietary protein guidance is the transition from protein requirements to recommendations. Hence, we discuss the refinement of protein/amino acid requirements for skeletal muscle maintenance with advanced age beyond simply the dose (e.g., source, type, quality, timing, pattern, nutrient co-ingestion) and explore the efficacy and sustainability of alternative protein sources beyond animal-based proteins to facilitate skeletal muscle remodeling in older age. We conclude that, whilst a growing body of research has demonstrated that animal-free protein sources can effectively stimulate support muscle remodeling in a manner that is comparable to animal-based proteins, food systems need to sustainably provide a diversity of both plant and animal source foods, not least for their protein content but other vital nutrients. Finally, we propose some priority research directions for the field of protein nutrition and healthy ageing.
KW - amino acids
KW - Dietary protein recommendations
KW - healthy ageing
KW - muscle protein synthesis
KW - recommended daily allowance
UR - http://www.scopus.com/inward/record.url?scp=85174326248&partnerID=8YFLogxK
U2 - 10.1017/S0029665123003750
DO - 10.1017/S0029665123003750
M3 - Journal article
C2 - 37818636
AN - SCOPUS:85174326248
JO - Proceedings of the Nutrition Society
JF - Proceedings of the Nutrition Society
SN - 0029-6651
ER -
ID: 371277480