Combined therapy with amifostine plus erythropoietin for the treatment of myelodysplastic syndromes.
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Combined therapy with amifostine plus erythropoietin for the treatment of myelodysplastic syndromes. / Musto, Pellegrino; Santini, Valeria; Balestri, Francesca; Fabbri, Alberto; Falcone, Antonietta; Sanpaolo, Grazia.
In: Haematologica, Vol. 87, No. 3, 2002, p. 322-3.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Combined therapy with amifostine plus erythropoietin for the treatment of myelodysplastic syndromes.
AU - Musto, Pellegrino
AU - Santini, Valeria
AU - Balestri, Francesca
AU - Fabbri, Alberto
AU - Falcone, Antonietta
AU - Sanpaolo, Grazia
N1 - Keywords: Aged; Aged, 80 and over; Amifostine; Drug Evaluation; Drug Therapy, Combination; Erythropoietin, Recombinant; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome
PY - 2002
Y1 - 2002
N2 - Twelve patients with myelodysplasia were treated with amifostine plus recombinant human erythropoietin (rHuEpo) for 6 weeks. A complete erythroid response was obtained in 2/12(16.6%) and a partial response in 4/12 (33.3%). Two of 8 patients with a platelet count < 100 x 10(9)/L had a complete response, as did 3/9 with a neutrophil count < 1.5 x 10(9)/L.Compared to rHuEpo or amifostine used as single agents, their combination did not offer substantial advantages.
AB - Twelve patients with myelodysplasia were treated with amifostine plus recombinant human erythropoietin (rHuEpo) for 6 weeks. A complete erythroid response was obtained in 2/12(16.6%) and a partial response in 4/12 (33.3%). Two of 8 patients with a platelet count < 100 x 10(9)/L had a complete response, as did 3/9 with a neutrophil count < 1.5 x 10(9)/L.Compared to rHuEpo or amifostine used as single agents, their combination did not offer substantial advantages.
M3 - Journal article
C2 - 11869946
VL - 87
SP - 322
EP - 323
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 3
ER -
ID: 8463466