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c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals. / Sourris, Karly C; Lyons, Jasmine G; de Courten, Maximilian; Dougherty, Sonia L; Henstridge, Darren C; Cooper, Mark E; Hage, Michelle; Dart, Anthony; Kingwell, Bronwyn A; Forbes, Josephine M; de Courten, Barbora.
In:
Diabetes, Vol. 58, No. 6, 01.06.2009, p. 1259-65.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Sourris, KC, Lyons, JG, de Courten, M, Dougherty, SL, Henstridge, DC, Cooper, ME, Hage, M, Dart, A, Kingwell, BA, Forbes, JM & de Courten, B 2009, '
c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals',
Diabetes, vol. 58, no. 6, pp. 1259-65.
https://doi.org/10.2337/db08-1725APA
Sourris, K. C., Lyons, J. G., de Courten, M., Dougherty, S. L., Henstridge, D. C., Cooper, M. E., Hage, M., Dart, A., Kingwell, B. A., Forbes, J. M., & de Courten, B. (2009).
c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals.
Diabetes,
58(6), 1259-65.
https://doi.org/10.2337/db08-1725Vancouver
Sourris KC, Lyons JG, de Courten M, Dougherty SL, Henstridge DC, Cooper ME et al.
c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals.
Diabetes. 2009 Jun 1;58(6):1259-65.
https://doi.org/10.2337/db08-1725Author
Sourris, Karly C ; Lyons, Jasmine G ; de Courten, Maximilian ; Dougherty, Sonia L ; Henstridge, Darren C ; Cooper, Mark E ; Hage, Michelle ; Dart, Anthony ; Kingwell, Bronwyn A ; Forbes, Josephine M ; de Courten, Barbora. / c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals. In: Diabetes. 2009 ; Vol. 58, No. 6. pp. 1259-65.
Bibtex
@article{0f8baec9d6814d0d8b410ff5751e8ac0,
title = "c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals",
abstract = "Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK) pathways-two pathways proposed as the link between CLAIS and insulin resistance.",
keywords = "Adolescent, Adult, Biopsy, Blood Glucose, Body Mass Index, Cell Nucleus, DNA Primers, Female, Humans, Insulin Resistance, JNK Mitogen-Activated Protein Kinases, Leukocyte Count, Leukocytes, Mononuclear, Male, Middle Aged, Mitogen-Activated Protein Kinase 8, Mitogen-Activated Protein Kinase 9, Muscle, Skeletal, NF-kappa B, Reference Values, Reverse Transcriptase Polymerase Chain Reaction, Subcutaneous Fat, Waist-Hip Ratio, Young Adult, eIF-2 Kinase",
author = "Sourris, {Karly C} and Lyons, {Jasmine G} and {de Courten}, Maximilian and Dougherty, {Sonia L} and Henstridge, {Darren C} and Cooper, {Mark E} and Michelle Hage and Anthony Dart and Kingwell, {Bronwyn A} and Forbes, {Josephine M} and {de Courten}, Barbora",
year = "2009",
month = jun,
day = "1",
doi = "10.2337/db08-1725",
language = "English",
volume = "58",
pages = "1259--65",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "6",
}
RIS
TY - JOUR
T1 - c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals
AU - Sourris, Karly C
AU - Lyons, Jasmine G
AU - de Courten, Maximilian
AU - Dougherty, Sonia L
AU - Henstridge, Darren C
AU - Cooper, Mark E
AU - Hage, Michelle
AU - Dart, Anthony
AU - Kingwell, Bronwyn A
AU - Forbes, Josephine M
AU - de Courten, Barbora
PY - 2009/6/1
Y1 - 2009/6/1
N2 - Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK) pathways-two pathways proposed as the link between CLAIS and insulin resistance.
AB - Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK) pathways-two pathways proposed as the link between CLAIS and insulin resistance.
KW - Adolescent
KW - Adult
KW - Biopsy
KW - Blood Glucose
KW - Body Mass Index
KW - Cell Nucleus
KW - DNA Primers
KW - Female
KW - Humans
KW - Insulin Resistance
KW - JNK Mitogen-Activated Protein Kinases
KW - Leukocyte Count
KW - Leukocytes, Mononuclear
KW - Male
KW - Middle Aged
KW - Mitogen-Activated Protein Kinase 8
KW - Mitogen-Activated Protein Kinase 9
KW - Muscle, Skeletal
KW - NF-kappa B
KW - Reference Values
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Subcutaneous Fat
KW - Waist-Hip Ratio
KW - Young Adult
KW - eIF-2 Kinase
U2 - 10.2337/db08-1725
DO - 10.2337/db08-1725
M3 - Journal article
C2 - 19258436
VL - 58
SP - 1259
EP - 1265
JO - Diabetes
JF - Diabetes
SN - 0012-1797
IS - 6
ER -
