Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice
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- Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice
Final published version, 3.65 MB, PDF document
Chronic cranial windows allow for longitudinal brain imaging experiments in awake, behaving mice. Different imaging technologies have their unique advantages and combining multiple imaging modalities offers measurements of a wide spectrum of neuronal, glial, vascular, and metabolic parameters needed for comprehensive investigation of physiological and pathophysiological mechanisms. Here, we detail a suite of surgical techniques for installation of different cranial windows targeted for specific imaging technologies and their combination. Following these techniques and practices will yield higher experimental success and reproducibility of results.
Original language | English |
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Article number | 612678 |
Journal | Frontiers in Physiology |
Volume | 11 |
Number of pages | 10 |
ISSN | 1664-042X |
DOIs | |
Publication status | Published - 2021 |
Bibliographical note
Publisher Copyright:
© Copyright © 2021 Kılıç, Desjardins, Tang, Thunemann, Sunil, Erdener, Postnov, Boas and Devor.
- awake, chronic, imaging, mice, multimodal, neural, vascular
Research areas
ID: 279430942