Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans

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Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. / Solomon, Thomas; Blannin, Andrew K.

In: Journal of Applied Physiology, Vol. 105, No. 6, 04.2009, p. 969-76.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Solomon, T & Blannin, AK 2009, 'Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans', Journal of Applied Physiology, vol. 105, no. 6, pp. 969-76. https://doi.org/10.1007/s00421-009-0986-9

APA

Solomon, T., & Blannin, A. K. (2009). Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. Journal of Applied Physiology, 105(6), 969-76. https://doi.org/10.1007/s00421-009-0986-9

Vancouver

Solomon T, Blannin AK. Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. Journal of Applied Physiology. 2009 Apr;105(6):969-76. https://doi.org/10.1007/s00421-009-0986-9

Author

Solomon, Thomas ; Blannin, Andrew K. / Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. In: Journal of Applied Physiology. 2009 ; Vol. 105, No. 6. pp. 969-76.

Bibtex

@article{ba177f89ce314dccb43eb8ac5f4b1305,
title = "Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans",
abstract = "Cinnamon can improve fasting glucose in humans yet data on insulin sensitivity are limited and controversial. Eight male volunteers (aged 25 +/- 1 years, body mass 76.5 +/- 3.0 kg, BMI 24.0 +/- 0.7 kg m(-2); mean +/- SEM) underwent two 14-day interventions involving cinnamon or placebo supplementation (3 g day(-1)). Placebo supplementation was continued for 5 days following this 14 day period. Oral glucose tolerance tests (OGTT) were performed on days 0, 1, 14, 16, 18, and 20. Cinnamon ingestion reduced the glucose response to OGTT on day 1 (-13.1 +/- 6.3% vs. day 0; P <0.05) and day 14 (-5.5 +/- 8.1% vs. day 0; P = 0.09). Cinnamon ingestion also reduced insulin responses to OGTT on day 14 (-27.1 +/- 6.2% vs. day 0; P <0.05), as well as improving insulin sensitivity on day 14 (vs. day 0; P <0.05). These effects were lost following cessation of cinnamon feeding. Cinnamon may improve glycaemic control and insulin sensitivity, but the effects are quickly reversed.",
keywords = "Adult, Blood Glucose, Cinnamomum zeylanicum, Cross-Over Studies, Diabetes Mellitus, Fasting, Glucose Tolerance Test, Humans, Insulin, Insulin Resistance, Male, Phytotherapy, Single-Blind Method",
author = "Thomas Solomon and Blannin, {Andrew K}",
year = "2009",
month = apr,
doi = "10.1007/s00421-009-0986-9",
language = "English",
volume = "105",
pages = "969--76",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "6",

}

RIS

TY - JOUR

T1 - Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans

AU - Solomon, Thomas

AU - Blannin, Andrew K

PY - 2009/4

Y1 - 2009/4

N2 - Cinnamon can improve fasting glucose in humans yet data on insulin sensitivity are limited and controversial. Eight male volunteers (aged 25 +/- 1 years, body mass 76.5 +/- 3.0 kg, BMI 24.0 +/- 0.7 kg m(-2); mean +/- SEM) underwent two 14-day interventions involving cinnamon or placebo supplementation (3 g day(-1)). Placebo supplementation was continued for 5 days following this 14 day period. Oral glucose tolerance tests (OGTT) were performed on days 0, 1, 14, 16, 18, and 20. Cinnamon ingestion reduced the glucose response to OGTT on day 1 (-13.1 +/- 6.3% vs. day 0; P <0.05) and day 14 (-5.5 +/- 8.1% vs. day 0; P = 0.09). Cinnamon ingestion also reduced insulin responses to OGTT on day 14 (-27.1 +/- 6.2% vs. day 0; P <0.05), as well as improving insulin sensitivity on day 14 (vs. day 0; P <0.05). These effects were lost following cessation of cinnamon feeding. Cinnamon may improve glycaemic control and insulin sensitivity, but the effects are quickly reversed.

AB - Cinnamon can improve fasting glucose in humans yet data on insulin sensitivity are limited and controversial. Eight male volunteers (aged 25 +/- 1 years, body mass 76.5 +/- 3.0 kg, BMI 24.0 +/- 0.7 kg m(-2); mean +/- SEM) underwent two 14-day interventions involving cinnamon or placebo supplementation (3 g day(-1)). Placebo supplementation was continued for 5 days following this 14 day period. Oral glucose tolerance tests (OGTT) were performed on days 0, 1, 14, 16, 18, and 20. Cinnamon ingestion reduced the glucose response to OGTT on day 1 (-13.1 +/- 6.3% vs. day 0; P <0.05) and day 14 (-5.5 +/- 8.1% vs. day 0; P = 0.09). Cinnamon ingestion also reduced insulin responses to OGTT on day 14 (-27.1 +/- 6.2% vs. day 0; P <0.05), as well as improving insulin sensitivity on day 14 (vs. day 0; P <0.05). These effects were lost following cessation of cinnamon feeding. Cinnamon may improve glycaemic control and insulin sensitivity, but the effects are quickly reversed.

KW - Adult

KW - Blood Glucose

KW - Cinnamomum zeylanicum

KW - Cross-Over Studies

KW - Diabetes Mellitus

KW - Fasting

KW - Glucose Tolerance Test

KW - Humans

KW - Insulin

KW - Insulin Resistance

KW - Male

KW - Phytotherapy

KW - Single-Blind Method

U2 - 10.1007/s00421-009-0986-9

DO - 10.1007/s00421-009-0986-9

M3 - Journal article

C2 - 19159947

VL - 105

SP - 969

EP - 976

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 6

ER -

ID: 50218504