Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice

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Standard

Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice. / Sölétormos, G; Fogh, J M; Sehested-Hansen, B; Spang-Thomsen, M; Schiøler, V; Dombernowsky, P; Skovsgaard, T.

In: European Journal of Cancer, Vol. 33, No. 1, 1997, p. 108-14.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sölétormos, G, Fogh, JM, Sehested-Hansen, B, Spang-Thomsen, M, Schiøler, V, Dombernowsky, P & Skovsgaard, T 1997, 'Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice', European Journal of Cancer, vol. 33, no. 1, pp. 108-14.

APA

Sölétormos, G., Fogh, J. M., Sehested-Hansen, B., Spang-Thomsen, M., Schiøler, V., Dombernowsky, P., & Skovsgaard, T. (1997). Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice. European Journal of Cancer, 33(1), 108-14.

Vancouver

Sölétormos G, Fogh JM, Sehested-Hansen B, Spang-Thomsen M, Schiøler V, Dombernowsky P et al. Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice. European Journal of Cancer. 1997;33(1):108-14.

Author

Sölétormos, G ; Fogh, J M ; Sehested-Hansen, B ; Spang-Thomsen, M ; Schiøler, V ; Dombernowsky, P ; Skovsgaard, T. / Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice. In: European Journal of Cancer. 1997 ; Vol. 33, No. 1. pp. 108-14.

Bibtex

@article{6ae0d36064b911de8bc9000ea68e967b,
title = "Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice",
abstract = "A set of experimental model systems were designed to investigate (a) the inter-relationship between growth of two human cancer cell lines (SK-CO-1, HT-29) and carcino-embryonic antigen (CEA) kinetics; and (b) whether neoplastic growth or CEA concentration is modulated by human growth hormone (hGH). We found that increasing CEA concentration depended on tumour burden. SK-CO-1 cells had the lowest growth rates but the highest rates of CEA production. The rate of CEA increase exceeded the growth rate of both SK-CO-1 and HT-29. hGH modulated neither neoplastic growth nor CEA production. In conclusion, our results suggest that experimental models may be useful for investigating the role of serological markers as monitors of increasing tumour burden. It will be of interest to investigate the performance of those model systems in examining the effect of cytotoxic agents in neoplastic growth.",
author = "G S{\"o}l{\'e}tormos and Fogh, {J M} and B Sehested-Hansen and M Spang-Thomsen and V Schi{\o}ler and P Dombernowsky and T Skovsgaard",
note = "Keywords: Adenocarcinoma; Animals; Carcinoembryonic Antigen; Colonic Neoplasms; Growth Hormone; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured",
year = "1997",
language = "English",
volume = "33",
pages = "108--14",
journal = "European Journal of Cancer, Supplement",
issn = "0959-8049",
publisher = "Pergamon",
number = "1",

}

RIS

TY - JOUR

T1 - Carcino-embryonic antigen in monitoring the growth of human colon adenocarcinoma tumour cells SK-CO-1 and HT-29 in vitro and in nude mice

AU - Sölétormos, G

AU - Fogh, J M

AU - Sehested-Hansen, B

AU - Spang-Thomsen, M

AU - Schiøler, V

AU - Dombernowsky, P

AU - Skovsgaard, T

N1 - Keywords: Adenocarcinoma; Animals; Carcinoembryonic Antigen; Colonic Neoplasms; Growth Hormone; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured

PY - 1997

Y1 - 1997

N2 - A set of experimental model systems were designed to investigate (a) the inter-relationship between growth of two human cancer cell lines (SK-CO-1, HT-29) and carcino-embryonic antigen (CEA) kinetics; and (b) whether neoplastic growth or CEA concentration is modulated by human growth hormone (hGH). We found that increasing CEA concentration depended on tumour burden. SK-CO-1 cells had the lowest growth rates but the highest rates of CEA production. The rate of CEA increase exceeded the growth rate of both SK-CO-1 and HT-29. hGH modulated neither neoplastic growth nor CEA production. In conclusion, our results suggest that experimental models may be useful for investigating the role of serological markers as monitors of increasing tumour burden. It will be of interest to investigate the performance of those model systems in examining the effect of cytotoxic agents in neoplastic growth.

AB - A set of experimental model systems were designed to investigate (a) the inter-relationship between growth of two human cancer cell lines (SK-CO-1, HT-29) and carcino-embryonic antigen (CEA) kinetics; and (b) whether neoplastic growth or CEA concentration is modulated by human growth hormone (hGH). We found that increasing CEA concentration depended on tumour burden. SK-CO-1 cells had the lowest growth rates but the highest rates of CEA production. The rate of CEA increase exceeded the growth rate of both SK-CO-1 and HT-29. hGH modulated neither neoplastic growth nor CEA production. In conclusion, our results suggest that experimental models may be useful for investigating the role of serological markers as monitors of increasing tumour burden. It will be of interest to investigate the performance of those model systems in examining the effect of cytotoxic agents in neoplastic growth.

M3 - Journal article

C2 - 9071909

VL - 33

SP - 108

EP - 114

JO - European Journal of Cancer, Supplement

JF - European Journal of Cancer, Supplement

SN - 0959-8049

IS - 1

ER -

ID: 12870173