Biochemical evaluation of endometrial function at the time of implantation

Research output: Contribution to journal › Review › Research › peer-review

Standard

Biochemical evaluation of endometrial function at the time of implantation. / Lindhard, Anette; Bentin-Ley, Ursula; Ravn, Vibeke; Islin, Henrik; Hviid, Thomas; Rex, Sven; Bangsbøll, Susanne; Sørensen, Steen.

In: Fertility and Sterility, Vol. 78, No. 2, 08.2002, p. 221-33.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Lindhard, A, Bentin-Ley, U, Ravn, V, Islin, H, Hviid, T, Rex, S, Bangsbøll, S & Sørensen, S 2002, 'Biochemical evaluation of endometrial function at the time of implantation', Fertility and Sterility, vol. 78, no. 2, pp. 221-33.

APA

Lindhard, A., Bentin-Ley, U., Ravn, V., Islin, H., Hviid, T., Rex, S., Bangsbøll, S., & Sørensen, S. (2002). Biochemical evaluation of endometrial function at the time of implantation. Fertility and Sterility, 78(2), 221-33.

Vancouver

Lindhard A, Bentin-Ley U, Ravn V, Islin H, Hviid T, Rex S et al. Biochemical evaluation of endometrial function at the time of implantation. Fertility and Sterility. 2002 Aug;78(2):221-33.

Author

Lindhard, Anette ; Bentin-Ley, Ursula ; Ravn, Vibeke ; Islin, Henrik ; Hviid, Thomas ; Rex, Sven ; Bangsbøll, Susanne ; Sørensen, Steen. / Biochemical evaluation of endometrial function at the time of implantation. In: Fertility and Sterility. 2002 ; Vol. 78, No. 2. pp. 221-33.

Bibtex

@article{f1d7430509354184bb43f04341cccf74,
title = "Biochemical evaluation of endometrial function at the time of implantation",
abstract = "OBJECTIVE: To review the literature on various endometrial factors assumed to be of importance to implantation and to evaluate their potential clinical value in the assessment of endometrial function at the time of implantation in infertile women in natural and stimulated cycles.DESIGN: Literature review.RESULT(S): Cytokines such as leukemia inhibitory factor, colony-stimulating factor-1, and interleukin-1 have all been shown to play important roles in the cascade of events that leads to implantation. They participate in a synchronized cooperation between the endometrium and the preimplanting embryo under the influence of steroid hormones. The same applies to the integrin alpha(v)beta(3), glycodelin, and the polymorphic mucin 1. The usefulness of these factors to assess endometrial receptivity and to estimate the prognosis for pregnancy in natural and artificial cycles remains to be proven.CONCLUSION(S): The studies performed to date have mostly included only small groups of patients with a lack of fertile controls, and only a few prospective, controlled trials have been carried out. Therefore, definite conclusions about the clinical value of these factors in the assessment of endometrial function and prognosis for pregnancy after artificial reproductive therapy cannot be drawn at present. Further evaluation of their importance for and function during implantation is needed.",
keywords = "Animals, Cytokines, Embryo Implantation, Endometrium, Female, Glycodelin, Glycoproteins, Growth Inhibitors, Humans, Infertility, Female, Interleukin-1, Interleukin-6, Leukemia Inhibitory Factor, Leukemia Inhibitory Factor Receptor alpha Subunit, Lymphokines, Macrophage Colony-Stimulating Factor, Menstruation, Models, Animal, Mucin-1, Pregnancy Proteins, Receptors, Cytokine, Receptors, OSM-LIF, Journal Article, Review",
author = "Anette Lindhard and Ursula Bentin-Ley and Vibeke Ravn and Henrik Islin and Thomas Hviid and Sven Rex and Susanne Bangsb{\o}ll and Steen S{\o}rensen",
year = "2002",
month = aug,
language = "English",
volume = "78",
pages = "221--33",
journal = "Sexuality, Reproduction and Menopause",
issn = "1546-2501",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Biochemical evaluation of endometrial function at the time of implantation

AU - Lindhard, Anette

AU - Bentin-Ley, Ursula

AU - Ravn, Vibeke

AU - Islin, Henrik

AU - Hviid, Thomas

AU - Rex, Sven

AU - Bangsbøll, Susanne

AU - Sørensen, Steen

PY - 2002/8

Y1 - 2002/8

N2 - OBJECTIVE: To review the literature on various endometrial factors assumed to be of importance to implantation and to evaluate their potential clinical value in the assessment of endometrial function at the time of implantation in infertile women in natural and stimulated cycles.DESIGN: Literature review.RESULT(S): Cytokines such as leukemia inhibitory factor, colony-stimulating factor-1, and interleukin-1 have all been shown to play important roles in the cascade of events that leads to implantation. They participate in a synchronized cooperation between the endometrium and the preimplanting embryo under the influence of steroid hormones. The same applies to the integrin alpha(v)beta(3), glycodelin, and the polymorphic mucin 1. The usefulness of these factors to assess endometrial receptivity and to estimate the prognosis for pregnancy in natural and artificial cycles remains to be proven.CONCLUSION(S): The studies performed to date have mostly included only small groups of patients with a lack of fertile controls, and only a few prospective, controlled trials have been carried out. Therefore, definite conclusions about the clinical value of these factors in the assessment of endometrial function and prognosis for pregnancy after artificial reproductive therapy cannot be drawn at present. Further evaluation of their importance for and function during implantation is needed.

AB - OBJECTIVE: To review the literature on various endometrial factors assumed to be of importance to implantation and to evaluate their potential clinical value in the assessment of endometrial function at the time of implantation in infertile women in natural and stimulated cycles.DESIGN: Literature review.RESULT(S): Cytokines such as leukemia inhibitory factor, colony-stimulating factor-1, and interleukin-1 have all been shown to play important roles in the cascade of events that leads to implantation. They participate in a synchronized cooperation between the endometrium and the preimplanting embryo under the influence of steroid hormones. The same applies to the integrin alpha(v)beta(3), glycodelin, and the polymorphic mucin 1. The usefulness of these factors to assess endometrial receptivity and to estimate the prognosis for pregnancy in natural and artificial cycles remains to be proven.CONCLUSION(S): The studies performed to date have mostly included only small groups of patients with a lack of fertile controls, and only a few prospective, controlled trials have been carried out. Therefore, definite conclusions about the clinical value of these factors in the assessment of endometrial function and prognosis for pregnancy after artificial reproductive therapy cannot be drawn at present. Further evaluation of their importance for and function during implantation is needed.

KW - Animals

KW - Cytokines

KW - Embryo Implantation

KW - Endometrium

KW - Female

KW - Glycodelin

KW - Glycoproteins

KW - Growth Inhibitors

KW - Humans

KW - Infertility, Female

KW - Interleukin-1

KW - Interleukin-6

KW - Leukemia Inhibitory Factor

KW - Leukemia Inhibitory Factor Receptor alpha Subunit

KW - Lymphokines

KW - Macrophage Colony-Stimulating Factor

KW - Menstruation

KW - Models, Animal

KW - Mucin-1

KW - Pregnancy Proteins

KW - Receptors, Cytokine

KW - Receptors, OSM-LIF

KW - Journal Article

KW - Review

M3 - Review

C2 - 12137855

VL - 78

SP - 221

EP - 233

JO - Sexuality, Reproduction and Menopause

JF - Sexuality, Reproduction and Menopause

SN - 1546-2501

IS - 2

ER -

ID: 188691880