Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

Research output: Contribution to journal › Journal article › Research › peer-review

  • B Z Alizadeh
  • P Hanifi-Moghaddam
  • P Eerligh
  • A R van der Slik
  • H Kolb
  • A V Kharagjitsingh
  • A M Pereira Arias
  • M Ronkainen
  • M Knip
  • R Bonfanti
  • E Bonifacio
  • Devendra Prasad
  • T Wilkin
  • M J Giphart
  • B P C Koeleman
  • R Nolsøe
  • Mandrup-Poulsen, Thomas
  • N C Schloot
  • B O Roep
  • DIABMARKER Study Group
We studied whether serum interferon (IFN)-gamma or interleukin (IL)-10 levels and their corresponding functional polymorphic genotypes are associated with partial remission of type 1 diabetes (T1D). A multi-centre study was undertaken in patients with newly diagnosed T1D and matched controls. T1D patients were followed for 3 months and characterized for remission status. Partial clinical remission was defined as a daily insulin dose
Original languageEnglish
JournalClinical and Experimental Immunology
Volume145
Issue number3
Pages (from-to)480-4
Number of pages5
ISSN0009-9104
DOIs
Publication statusPublished - 1 Sep 2006

    Research areas

  • Analysis of Variance, Biological Markers, Case-Control Studies, Chi-Square Distribution, Diabetes Mellitus, Type 1, Genetic Predisposition to Disease, Genotype, Humans, Interferon-gamma, Interleukin-10, Remission, Spontaneous, Sample Size

ID: 33902104