Department of Biomedical Sciences

  1. 2023
  2. Published

    Ligand entry pathways control the chemical space recognized by GPR183

    Kjær, Viktoria Madeline Skovgaard, Stępniewski, T. M., Medel-Lacruz, B., Reinmuth, L., Ciba, Marija, Ulven, Elisabeth Rexen, Bonomi, M., Selent, J. & Rosenkilde, Mette, 2023, In: Chemical Science. 14, 39, p. 10671-10683

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Ligand selectivity hotspots in serotonin GPCRs

    Simon, Icaro A, Bjørn-Yoshimoto, Walden, Harpsøe, Kasper, Iliadis, S., Svensson, B., Jensen, Anders A. & Gloriam, David E., 2023, In: Trends in Pharmacological Sciences. 44, 12, p. 978-990

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

    Unterweger, Iris Anne, Klepstad, J., Hannezo, E., Lundegaard, Pia Rengtved, Trusina, Ala & Ober, Elke, 2023, In: PLOS Biology. 21, 10, 30 p., e3002315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Link between myocardial deformation phenotyping using longitudinal and circumferential strain and risk of incident heart failure and cardiovascular death

    Skaarup, K. G., Lassen, M. C. H., Johansen, N. D., Sengeløv, M., Olsen, F. J., Jensen, G. B., Schnohr, P., Shah, A., Claggett, B. L., Solomon, S. D., Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: European Heart Journal Cardiovascular Imaging. 24, 8, p. 999-1006 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses

    Carstensen, Helena, Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., van Hunnik, A., Hohl, M., Sattler, Stefan M, Fløgstad, C., Hopster-Iversen, Charlotte, Verheule, S., Böhm, M., Schotten, U., Jespersen, Thomas & Buhl, Rikke, 2023, In: Journal of Cardiovascular Translational Research. 16, p. 1205–1219

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Long-term monitoring with an implantable loop recorder detects multiple episodes of paroxysmal atrial fibrillation after electrical cardioversion in a Warmblood horse

    Kjeldsen, S. T., Jensen, M., Sørensen, C. T., Hopster-Iversen, Charlotte & Nissen, Sarah Dalgas, 2023, In: Equine Veterinary Education. 35, 7, p. 340-346 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Long-term non-invasive ventilation for COPD patients following an exacerbation with acute hypercapnic respiratory failure: a randomized controlled trial

    Hedsund, C., Linde Ankjærgaard, K., Peick Sonne, T., Tønnesen, P., Frausing Hansen, E., Frost Andreassen, H., Berg, Ronan Martin Griffin, Jensen , Jens-Ulrik Stæhr & Wilcke, Jon Torgny Rostrup, 2023, In: European Clinical Respiratory Journal. 10, 1, 2257993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Long-term stability of thyroid peroxidase antibody (anti-TPO) in serum in the Danish General Suburban Population Study

    Jensen, Christian Zinck, Nygaard, Birte, Faber, J., Pedersen, P. L., Larsen, Morten Kranker, Kanters, Jørgen K., Poulsen, Henrik Enghusen, Kellogg, M. & Ellervik, Christina, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 9, 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published
  14. Published

    Loss of Adgra3 causes obstructive azoospermia with high penetrance in male mice

    Nybo, Maja Lind, Kvam, J. M., Nielsen, J. E., Frederiksen, H., Spiess, Katja, Jensen, Kristian HR, Gadgaard, S., Walser, Anna Louise Silvia, Thomsen, J. S., Cowin, P., Juul, Anders, Jensen, M. B. & Rosenkilde, Mette, 2023, In: FASEB Journal. 37, 2, 13 p., 22781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading

    Berg, P., Jensen, T., Andersen, J. F., Svendsen, S. L., Modvig, Ida Marie, Wang, T., Frische, S., Chow, B. K. C., Malte, H., Holst, Jens Juul, Sørensen, M. V. & Leipziger, J., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 8, p. 1329-1342 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals

    Wang, J., Mogensen, A. M. G., Thybo, F., Brandbyge, M., Brorson, J., van Hall, Gerrit, Agergaard, J., de Paoli, F. V., Miller, B. F., Bøtker, H. E., Farup, J. & Vissing, K., 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 134, 4, p. 1047-1062 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    MRI-Induced Neurosensory Events in Decorative Black Tattoos: Study by Advanced Experimental Methods

    Alsing, K. K., Olsen, O., Bender Koch, Christian, Hansen, R. H., Persson, Daniel Pergament, Qvortrup, Klaus & Serup, J., 2023, In: Case Reports in Dermatology. 15, 1, p. 85-92

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Maternal obesity, interpregnancy weight changes and congenital heart defects in the offspring

    Hedermann, G., Thagaard, I. N., Hedley, P. L., Krebs, Lone, Hagen, C. M., Sørensen, Thorkild I.A., Christiansen, Michael & Ekelund, Charlotte Kvist, 2023, medRxiv, 20 p.

    Research output: Working paperPreprintResearch

  20. Published

    Mechanisms of a Mycobacterium tuberculosis Active Peptide

    Rao, K. U., Li, P., Welinder, C., Tenland, E., Gourdon, Pontus Emanuel, Sturegård, E., Ho, J. C. S. & Godaly, G., 2023, In: Pharmaceutics. 15, 2, 16 p., 540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Mechanisms underlying the blood pressure-lowering effects of empagliflozin, losartan and their combination in people with type 2 diabetes: A secondary analysis of a randomized crossover trial

    Scholtes, R. A., Mosterd, C. M., Hesp, A. C., Smits, Mark, Heerspink, H. J. L. & van Raalte, D. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 198-207

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Medicinal plant rosemary relaxes blood vessels by activating vascular smooth muscle KCNQ channels

    Manville, R. W., Baldwin, S. N., Eriksen, E. Ø., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2023, In: FASEB Journal. 37, 9, p. 1-15 e23125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins

    Vadmand, A. C., Nissen, A. A., Mathiesen, S., Ebbesen, M. S., Gerbek, T., Fridh, M. K., Sørensen, K., Hartmann, Bolette, Holst, Jens Juul & Muller, Klaus, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 2, p. 453–462

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Methods to Estimate Energy Expenditure, Physical Activity, and Sedentary Time in Pregnant Women: A Validation Study Using Doubly Labeled Water

    Alomairah, S. A., Knudsen, S. D. P., Roland, Caroline Borup, Hergel, I. M., Mølsted, Stig, Clausen, Tine Dalsgaard, Løkkegaard, Ellen Christine Leth, Bendix, J. M., Maddison, R., Löf, M., Larsen, J. E., van Hall, Gerrit & Stallknecht, Bente Merete, 2023, In: Journal for the Measurement of Physical Behaviour . 6, 1, p. 88-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Methylation and hydroxymethylation in cancer

    Asmar, F., Gillberg, Linn & Grønbæk, Kirsten, 2023, Epigenetic Cancer Therapy [Second Edition]. 2. ed. Elsevier, p. 11-37 27 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle

    Knudsen, Jonas Roland, Persson, K. W., Henriquez-Olguín, Carlos, Li, Z., Di Leo, N., Hesselager, S. A., Raun, Steffen Henning, Hingst, J. R., Trouillon, R., Wohlwend, M., Wojtaszewski, Jørgen F P, Gijs, M. A. M. & Jensen, Thomas Elbenhardt, 2023, In: eLife. 12, 24 p., e83338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Mild-to-moderate severity of psoriasis may be assessed remotely based on photographs and self-reported extent of skin involvement

    Ali, Z., Robert Zibert, J., Dahiya, P., Bachdal Johansen, C., Grønlund Holm, J., Ravn Jørgensen, A. H., Manole, I., Suru, A., Egeberg, Alexander, Thomsen, Simon Francis & Andersen, A. D., 2023, In: JAAD International. 11, p. 129-136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

    Rusiecka, O. M., Molica, F., Nielsen, Morten Schak, Tollance, A., Morel, S., Frieden, M., Chanson, M., Boengler, K. & Kwak, B. R., 2023, In: Cardiovascular Research. 119, 13, p. 2342-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl) alters their reactivity with vascular smooth muscle cells.

    Hartsema, Els Alletta, Hallberg, L. A. E., Barlous, K. A. & Hawkins, Clare Louise, 2023, In: Redox Biochemistry and Biology. 5-6, 11 p., 100010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Molecular exploration of fossil eggshell uncovers hidden lineage of giant extinct bird

    Grealy, A., Miller, G. H., Phillips, M. J., Clarke, S. J., Fogel, M., Patalwala, D., Rigby, P., Hubbard, A., Demarchi, B., Collins, Matthew James, Mackie, Meaghan, Sakalauskaite, J., Stiller, Josefin, Clarke, J. A., Legendre, L. J., Douglass, K., Hansford, J., Haile, J. & Bunce, M., 2023, In: Nature Communications. 14, 14 p., 914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation

    Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, Per Mårten, Grune, T., Davies, Michael J., Bartesaghi, S. & Radi, R., 2023, In: Journal of Biological Chemistry. 299, 3, 22 p., 102941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Muscarinic acetylcholine receptors M2 are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block

    Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, T. H., Hesselkilde, E. M., Kjeldsen, S. T., Hopster-Iversen, Charlotte, D’Souza, A., Jespersen, Thomas & Buhl, Rikke, 2023, In: Frontiers in Cardiovascular Medicine. 10, 10 p., 1102164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival

    Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography

    Lassen, Martin Lyngby, Rasmussen, T., Byrne, C., Holmvang, Lene, Kjær, Andreas & Hasbak, P., 2023, In: Journal of Nuclear Cardiology. 30, 5, p. 2289-2300

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State

    Lewis, Christopher T.A. & Ochala, Julien, 2023, In: Physiology. 38, 1, p. 3-9

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations

    Sonne, A., Peverelli, L., Hernandez-Lain, A., Domínguez-González, C., Andersen, J. L., Milone, M., Beggs, A. H. & Ochala, Julien, 2023, In: American journal of physiology. Cell physiology. 324, 3, p. C769–C776 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle

    Henriquez-Olguín, Carlos, Meneses Valdés, Roberto Andrés, Raun, Steffen Henning, Gallero, S., Knudsen, Jonas Roland, Li, Z., Li, J., Sylow, Lykke, Jaimovich, E. & Jensen, Thomas Elbenhardt, 2023, In: Redox Biology. 65, 12 p., 102842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Nationwide Utilization of Danish Government Electronic letter system for increasing inFLUenza vaccine uptake (NUDGE-FLU): Study protocol for a nationwide randomized implementation trial

    Johansen, N. D., Vaduganathan, M., Bhatt, A. S., Lee, S. G., Modin, D., Claggett, B. L., Dueger, E. L., Samson, S., Loiacono, M. M., Køber, Lars Valeur, Solomon, S. D., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Valentiner-Branth, P., Krause, T. G. & Biering-Sørensen, Tor, 2023, In: American Heart Journal. 260, p. 58-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Neoadjuvant Gold Nanoshell-Based Photothermal Therapy Combined with Liposomal Doxorubicin in a Mouse Model of Colorectal Cancer

    Simón, M., Jørgensen, Jesper Tranekjær, Norregaard, K., Henriksen, J. R., Clergeaud, G., Andresen, T. L., Hansen, A. E. & Kjær, Andreas, 2023, In: International Journal of Nanomedicine. 18, p. 829-841

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers

    Jensen, M., Thorsen, N. W., Hallberg, L. A. E., Hägglund, Per Mårten & Hawkins, Clare Louise, 2023, In: Free Radical Biology and Medicine. 202, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Next-Level Natriuretic Peptide Measurement

    Nersting, J., Terzic, D., Hansen, L. H. & Goetze, Jens P. , 2023, In: Clinical Chemistry. 69, 4, p. 313-315 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  47. Published

    No diurnal variation is present in maximal fat oxidation during exercise in young healthy women: A cross-over study

    Robles-González, L., Aguilar-Navarro, M., López-Samanes, Á., Ruiz-Moreno, C., Muñoz, A., Varillas-Delgado, D., Gutiérrez-Hellín, J., Helge, Jørn Wulff, Ruiz, J. R. & Amaro-Gahete, F. J., 2023, In: European Journal of Sport Science. 23, 6, p. 936–942

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events

    Shahrbabaki, S. S., Dr Linz, Dominik Karl & Baumert, M., 2023, In: International Journal of Cardiology. 385, p. 55-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Non-invasive methods to assess muscle function in dogs: A scoping review

    Dahl, Kathrine Højte, Zebis, Mette Kreutzfeldt, Vitger, Anne Désiré, Miles, James Edward & Alkjær, Tine, 2023, In: Frontiers in Veterinary Science. 10, p. 1-10 1116854.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Normal Values and Reference Ranges for the Ratio of Transmitral Early Filling Velocity to Early Diastolic Strain Rate: The Copenhagen City Heart Study

    Lassen, M. C. H., Skaarup, K. G., Johansen, N. D., Olsen, F. J., Qasim, A. N., Jensen, G. B., Schnohr, P., Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Journal of the American Society of Echocardiography. 30, 11, p. 1204-1212

    Research output: Contribution to journalJournal articleResearchpeer-review