Department of Biomedical Sciences

  1. 2024
  2. Published

    Efficacy and safety of ligelizumab in adults and adolescents with chronic spontaneous urticaria: results of two phase 3 randomised controlled trials

    PEARL-1 and PEARL-2 trial investigators, P. A. P. T. I., 2024, In: Lancet (London, England). 403, 10422, p. 147-159 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Elderly male patients with hidradenitis suppurativa have more severe disease independent of disease duration

    Nielsen, V. W., Ring, H. C., Holgersen, N. & Thomsen, Simon Francis, 2024, In: British Journal of Dermatology. 190, 2, p. 292-293

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Electrocardiographic markers in patients with type 2 diabetes and the role of diabetes duration

    Isaksen, Jonas L., Sivertsen, C. B., Jensen, Christian Zinck, Graff, C., Dr Linz, Dominik Karl, Ellervik, Christina, Jensen, M. T., Jørgensen, P. G. & Kanters, Jørgen K., 2024, In: Journal of Electrocardiology. 84, p. 129-136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Electronic nudges increase influenza vaccination utilization after myocardial infarction: the nationwide NUDGE-FLU implementation trial

    Bhatt, A. S., Johansen, N. D., Modin, D., Claggett, B. L., Dueger, E. L., Samson, S. I., Loiacono, M. M., Køber, Lars Valeur, Solomon, S. D., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Martel, C. J., Vaduganathan, M. & Biering-Sørensen, Tor, 2024, In: European Heart Journal. 45, 20, p. 1856–1858 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Elevated levels of iodide promote peroxidase-mediated protein iodination and inhibit protein chlorination

    Jokumsen, Kathrine Væver, Huhle, V. H., Hägglund, Per Mårten, Davies, Michael J. & Gamon, Luke Francis, 2024, In: Free Radical Biology and Medicine. 220, p. 207-221 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Elevated plasma apolipoprotein E levels in people living with HIV: Associations with biomarkers and HIV-specific risk factors

    Jensen, Anne Marie Reimer, Frikke-Schmidt, Ruth, Gelpi, M., Knudsen, A. D., Benfield, Thomas, Nordestgaard, Børge, Afzal, Shoaib, Biering-Sørensen, Tor & Nielsen, Susanne Dam, 2024, In: Atherosclerosis. 390, 6 p., 117457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

    Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

    Baekdal, M., Nielsen, S. W., Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2024, In: Diabetes Care. 47, 1, p. 71-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Endocannabinoid-related molecules predict the metabolic efficacy of GLP-1 receptor agonism in humans with obesity

    Matias, I., Lehmann, E. W., Zizzari, P., Byberg, Sarah, Cota, D., Torekov, Signe Sørensen & Quarta, C., 2024, In: Journal of Endocrinological Investigation. 43, p. 1289–1294

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Epicardial adipose tissue and subclinical incident atrial fibrillation as detected by continuous monitoring: a cardiac magnetic resonance imaging study

    Guldberg, E., Diederichsen, S. Z., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Olesen, Morten Steen Salling, Højberg, S., Køber, Lars Valeur, Vejlstrup, N., Bertelsen, L. & Svendsen, Jesper Hastrup, 2024, In: International Journal of Cardiovascular Imaging. 40, p. 591–599

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evaluating the inhibition of IL-17A and TNFα in a cartilage explant model cultured with Th17-derived cytokines

    Groen, S. S., Bay-Jensen, A. C., Thudium, C. S., Dziegiel, Morten Hanefeld, Skougaard, M., Thomsen, Simon Francis & Nielsen, S. H., 2024, In: Journal of Translational Autoimmunity. 8, 100231.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Even mild mitral regurgitation is associated with incident atrial fibrillation in the general population

    Yafasov, M., Olsen, F. J., Shabib, A., Skaarup, K. G., Lassen, M. C. H., Johansen, N. D., Jensen, M. T., Jensen, G. B., Schnohr, P., Møgelvang, R. & Biering-Sørensen, Tor, 2024, In: European Heart Journal Cardiovascular Imaging. 25, 5, p. 579–586

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. E-pub ahead of print

    Exercise-induced changes in left ventricular strain are affected by interleukin-6 activity: An exploratory analysis of a randomised-controlled trial in humans with abdominal obesity

    Jønck, S., Olsen, Mathilde Løk, Durrer, C., Wedell-Neergaard, A. S., Lehrskov, L. L., Legaard, G. E., Krogh-Madsen, Rikke, Rosenmeier, J., Lund, Morten Asp Vonsild, Pedersen, Bente Klarlund, Ellingsgaard, H., Berg, Ronan Martin Griffin & Christensen, R. H., 2024, (E-pub ahead of print) In: Experimental Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Experiences with pre-graduate research among Danish medical students and doctors

    Zhang, D. G., Zahid, Jawad Ahmad, Hadi, N. A. H. & Thomsen, Simon Francis, 2024, In: Danish Medical Journal. 2024, 4, A09230610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Extracellular matrix turnover proteins as risk markers in people with type 2 diabetes and microalbuminuria

    Skriver-Møller, A. C., Møller, A. L., Blond, Martin Bæk, Rasmussen, D. G. K., Genovese, F., Reinhard, H., von Scholten, B. J., Jacobsen, P. K., Parving, H. H., Karsdal, M. A., Hansen, Tine Willum & Rossing, Peter, 2024, In: Journal of Diabetes and its Complications. 38, 6, 6 p., 108765.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. E-pub ahead of print

    Factors associated with development of post-operative reflux in horses with large colon volvulus and association with complications and outcomes

    Watrobska, N., Gough, R., Hallowell, G., Haugaard, Simon Libak & McGovern, K. F., 2024, (E-pub ahead of print) In: Equine Veterinary Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. E-pub ahead of print

    Fatigue is associated with disease severity in adult patients with hidradenitis suppurativa

    Chodziuk, A., Holgersen, N., Nielsen, V. W., Thyssen, Jacob Pontoppidan, Egeberg, Alexander & Thomsen, Simon Francis, 2024, (E-pub ahead of print) In: JEADV Clinical Practice.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. E-pub ahead of print

    Feasibility and diagnostic performance of sentinel node biopsy for staging cN0 oral squamous cell carcinoma in a previously treated neck

    Mørch, T., Tvedskov, Jesper Filtenborg, Wessel, Irene , Charabi, Birgitte Wittenborg, Jakobsen, K. K., Grønhøj, Christian, Kiss, K., Lelkaitis, G., Mortensen, Jann, Kjær, Andreas, von Buchwald, Christian & Christensen, Anders, 2024, (E-pub ahead of print) In: World Journal of Otorhinolaryngology - Head and Neck Surgery.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Fibroblast Activation Protein (FAP)-Mediated Cleavage of Type III Collagen Reveals Serum Biomarker Potential in Non-Small Cell Lung Cancer and Spondyloarthritis

    Pedersen, Rasmus Sund, Thorlacius-Ussing, J., Raimondo, M. G., Langholm, L. L., Schett, G., Ramming, A., Karsdal, M. & Willumsen, N., 2024, In: Biomedicines. 12, 3, 13 p., 545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. E-pub ahead of print

    First, do no harm: A call to action to improve the evaluation of harms in clinical exercise research

    Thomsen, S. N., Lucia, A., Spence, R. R., Benatti, F. B., Joyner, M. J., Berg, Ronan Martin Griffin, Ried-Larsen, M. & Simonsen, C., 2024, (E-pub ahead of print) In: British Journal of Sports Medicine. bjsports-2023-107579.

    Research output: Contribution to journalEditorialResearchpeer-review

  23. Published

    Focal point-by-point biphasic monopolar pulsed field ablation for posterior wall isolation

    Farnir, F., Chaldoupi, S. M., Farnir, F., Schotten, U., Vernooy, K., Luermans, J. & Dr Linz, Dominik Karl, 2024, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 26, 4, 3 p., euae077 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Focal point-by-point pulsed field ablation for the treatment of atrial arrhythmias in patients with challenging anatomy where radiofrequency ablation cannot be applied: A case series

    Farnir, F., Luermans, J., Manusama, R., den Uijl, D., Chaldoupi, S. M. & Dr Linz, Dominik Karl, 2024, In: HeartRhythm Case Reports. 10, 1, p. 21-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Frequency and risk factors of atrial fibrillation after acute abdominal surgery: A prospective cohort study

    Madsen, C. L., Leerhøy, B., Jørgensen, Lars Nannestad, Meyhoff, Christian Sylvest, Sajadieh, Ahmad & Dominguez, Helena, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 345-353 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    From biochemical markers to molecular endotypes of osteoarthritis: a review on validated biomarkers

    Hannani, Monica, Thudium, C. S., Karsdal, M. A., Ladel, C., Mobasheri, A., Uebelhoer, M., Larkin, J., Bacardit, J., Struglics, A. & Bay-Jensen, A. C., 2024, In: Expert Review of Molecular Diagnostics. 24, 1-2, p. 23-38

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology

    Rosenkilde, Mette, Lindquist, Peter, Kizilkaya, Hüsün Sheyma & Gasbjerg, Lærke Smidt, 2024, In: Peptides. 177, 14 p., 171212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    GLP-1-directed NMDA receptor antagonism for obesity treatment

    Petersen, J., Ludwig, M. Q., Juozaityte, V., Ranea-Robles, P., Svendsen, C., Hwang, E., Kristensen, A. W., Fadahunsi, N., Lund, J., Breum, A. W., Mathiesen, C. V., Sachs, L., Moreno-Justicia, R., Rohlfs, R., Ford, J. C., Douros, J. D., Finan, B., Portillo, B., Grose, K., Petersen, J. E. & 13 others, Trauelsen, Mette, Feuchtinger, A., DiMarchi, R. D., Schwartz, Thue W., Deshmukh, Atul Shahaji, Thomsen, Morten Bækgaard, Kohlmeier, Kristi Anne, Williams, K. W., Pers, Tune H, Frølund, Bente, Strømgaard, Kristian, Klein, A. B. & Clemmensen, Christoffer, 2024, In: Nature. 629, 8014, p. 1133–1141

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms

    Richter, Michael Martin, Kemp, I. M., Heebøll, S., Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, Mikael Ploug, Madsbad, Sten, Schiødt, Frank Vinholt, Nørgaard, Kirsten, Schmidt, S., Gluud, Lise Lotte, Haugaard, Steen Bendix, Holst, Jens Juul, Nielsen, S., Rungby, Jørgen & Albrechtsen, Nicolai Jacob Wewer, 2024, In: Metabolism: Clinical and Experimental. 156, 13 p., 155915.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals

    Kliim-Hansen, V., Gether, I. M., Juel, C. T., Ellegaard, A., Pedersen, M. G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Lund, Asger Bach, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2024, In: Peptides. 179, 5 p., 171242.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Glucose turnover at whole-body and skeletal muscle level in response to parenteral nutrition in male patients with alcoholic liver cirrhosis

    Trinh, B., Rasmussen Rinnov, A., Iepsen, Ulrik Winning, Winding Munch, G., Munch Winding, K., Lauridsen, C., Gluud, Lise Lotte, van Hall, Gerrit & Ellingsgaard, H., 2024, In: Clinical Nutrition ESPEN. 60, p. 240-246

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. E-pub ahead of print

    Glycolysis inhibition affects proliferation and cytotoxicity of Vγ9Vδ2 T cells expanded for adoptive cell therapy

    Aehnlich, P., Santiago, M. V., Dam, S. H., Saló, S. F., Rahbech, Anne, Olsen, L. R., thor Straten, P., Desler, Claus & Holmen Olofsson, G., 2024, (E-pub ahead of print) In: Cytotherapy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    HER2-targeted, enzyme-activated liposomes show superior in vivo efficacy in an ovarian cancer model

    Juul, C. A., Engel, T. B., Fliedner, F. P., Ringgaard, L., Eliasen, R., Melander, F., Bak, M., Kjær, Andreas, Henriksen, J. R., Elema, D. R., Hansen, A. E. & Andresen, T. L., 2024, In: Journal of Controlled Release. 371, p. 288-297

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published

    Host defense peptides human β defensin 2 and LL-37 ameliorate murine necrotizing enterocolitis

    Lueschow-Guijosa, S. R., Stanford, A. H., Berger, J. N., Gong, H., Boly, T. J., Jensen, Benjamin Anderschou Holbech, Nordkild, P., Leegwater, A. J., Wehkamp, J., Underwood, M. A. & McElroy, S. J., 2024, In: iScience. 27, 6, 21 p., 109993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Immunohistochemical characterization of integrin alfa 6 in uterus and cervix of the cynomolgus monkeys (Macaca fascicularis) with MfPV3 infection

    Setyawaty, D., Mariya, S., Prabandari, S. A., Boilessen, D. R., Holst, Peter Johannes & Darusman, H. S., 2024, In: Journal of Medical Primatology. 53, 1, 6 p., e12690.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Impact of COVID-19 restrictions on the treatment of neovascular age-related macular degeneration

    Bagi Nordsten, C., Rasmussen, B. K., Li, Xiaoqiang, Thomsen, Alexander Kai & Sørensen, Torben Lykke, 2024, In: Acta Ophthalmologica. 102, 3, p. e404-e405 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    Impact of Synbiotic Intake on Liver Metabolism in Metabolically Healthy Participants and Its Potential Preventive Effect on Metabolic-Dysfunction-Associated Fatty Liver Disease (MAFLD): A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial

    Mantri, A., Köhlmoos, A., Schelski, D. S., Seel, W., Stoffel-Wagner, B., Krawitz, P., Stehle, P., Holst, Jens Juul, Weber, B., Koban, L., Plassmann, H. & Simon, M. C., 2024, In: Nutrients. 16, 9, 14 p., 1300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. E-pub ahead of print

    Impedance drop during focal monopolar pulsed field ablation in the atrium

    Farnir, F. I. P., Luermans, J. G. L. M., Farnir, F. P. F. J. D. J., Chaldoupi, S. M. & Dr Linz, Dominik Karl, 2024, (E-pub ahead of print) In: Journal of Interventional Cardiac Electrophysiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. Published

    Improving post-MI risk stratification with pressure-strain loops: Work in progress

    Olsen, F. J., Smiseth, O. A. & Biering-Sørensen, Tor, 2024, In: International Journal of Cardiology. 402, 3 p., 131866.

    Research output: Contribution to journalEditorialResearchpeer-review

  42. Published
  43. E-pub ahead of print

    Incidence of premature battery depletion in subcutaneous cardioverter-defibrillator patients: insights from a multicenter registry

    Lüker, J., Strik, M., Andrade, J. G., Raymond-Paquin, A., Elrefai, M. H., Roberts, P. R., Pérez, Ó. C., Kron, J., Koneru, J., Franqui-Rivera, H., Sultan, A., Ernst, A., Schmitt, J., Pott, A., Veltmann, C., Srinivasan, N. T., Collinson, J., van Stipdonk, A. M. W., Linz, D., Fluschnik, N. & 4 others, Tönnis, T., Haeberlin, A., Ploux, S. & Steven, D., 2024, (E-pub ahead of print) In: Journal of Interventional Cardiac Electrophysiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Increased sub-clinical coronary artery pathology in type 2 diabetes with albuminuria

    Rasmussen, I. K. B., Skriver-Moeller, A., Ripa, Rasmus Sejersten, Hasbak, P., Wasehuus, V. S., lvs502, lvs502, Zobel, E. H., Lassen, Martin Lyngby, Holmvang, Lene, Slomka, P., Rossing, Peter, Kjær, Andreas & Hansen, T. W., 2024, In: Diabetes. 73, 3, p. 490–496 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

    Smits, Mark, Dreyer, S. I. L., Dal, Jenna Elizabeth Hunt, Drzazga, Anna Katarzyna, Modvig, Ida Marie, Holst, Jens Juul & Kissow, Hannelouise, 2024, In: Frontiers in Endocrinology. 15, 10 p., 1362711.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis

    Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, Baras, A., Mirshahi, T., Carey, D. J., Kaplan, D. E., Lynch, J., Morgan, T., Schwantes-An, T., Dochtermann, D. R., Pyarajan, S., Tsao, P. S., Laisk, T., Mägi, R., Kozlitina, J., Tybjærg-Hansen, Anne, Jones, D., Knowlton, K. U., Nadauld, L., Ferkingstad, E., Björnsson, E. S., Ulfarsson, M. O., Sturluson, Á., Sulem, P., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Gudbjartsson, D. F., Stefansson, K., Olesen, Morten Steen Salling, Chang, K., Bundgård, Henning, Stender, Stefan & DBDS Genomic Consortium, D. G. C., 2024, In: Nature Genetics. 56, p. 827–837 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Interleukin-8 Promoter Polymorphism -251 A/T and Treatment Response in Neovascular Age-related Macular Degeneration

    Thomsen, Alexander Kai, Krogh Nielsen, M., Liisborg, C. & Sørensen, Torben Lykke, 2024, In: Clinical ophthalmology (Auckland, N.Z.). 18, p. 537-543 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans

    Englund, A., Gilliam-Vigh, H., Suppli, M. P., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 7 p., 171227.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Investigating protease-mediated peptides of inflammation and tissue remodeling as biomarkers associated with flares in psoriatic arthritis

    Groen, S. S., Nielsen, S. H., Bay-Jensen, A. C., Rasti, M., Ganatra, D., Oikonomopoulou, K. & Chandran, V., 2024, In: Arthritis Research and Therapy. 26, 1, 13 p., 107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
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