Department of Biomedical Sciences

  1. 2022
  2. Published

    Experimental Model of Pulmonary Inflammation Induced by SARS-CoV-2 Spike Protein and Endotoxin

    Puthia, M., Tanner, L., Petruk, G. & Schmidtchen, A., 11 Mar 2022, In: ACS Pharmacology and Translational Science. 5, 3, p. 141-148 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial

    Eveleens Maarse, B. C., Graff, C., Kanters, Jørgen K., van Esdonk, M. J., Kemme, M. J. B., in 't Veld, A. E., Jansen, M. A. A., Moerland, M. & Gal, P., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1054-1062 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Hemoglobin-based oxygen carriers camouflaged with membranes extracted from red blood cells: Optimization and assessment of functionality

    Jansman, M. M. T., Coll-Satue, C., Liu, X., Kempen, Paul Joseph, Andresen, T. L., Thulstrup, Peter Waaben & Hosta-Rigau, L., Mar 2022, In: Biomaterials advances. 134, 15 p., 112691.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pharmacological inhibition of acetylcholine-regulated potassium current (IK,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events

    Linz, Benedikt Maximilian, Thostrup, A. H., Saljic, Arnela, Rombouts, K., Hertel, Julie Norup, Hohl, M., Milnes, J., Tfelt-Hansen, Jacob, Dr Linz, Dominik Karl & Jespersen, Thomas, Feb 2022, In: Heart Rhythm O2. 3, 1, p. 97-104

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation

    Jensen, Sune K. , Pærregaard, S. I., Brandum, E. P., Jørgensen, Astrid Sissel, Hjortø, Gertrud Malene & Jensen, Benjamin Anderschou Holbech, 25 Jan 2022, In: Gastroenterology Report. 10, p. 1-15 goac008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published
  9. Published

    NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy

    Ranu, N., Laitila, J., Dugdale, H. F., Mariano, J., Kolb, J. S., Wallgren-Pettersson, C., Witting, N., Vissing, J., Vilchez, J. J., Fiorillo, C., Zanoteli, E., Auranen, M., Jokela, M., Tasca, G., Claeys, K. G., Voermans, N. C., Palmio, J., Huovinen, S., Moggio, M., Beck, T. N. & 3 others, Kontrogianni-Konstantopoulos, A., Granzier, H. & Ochala, Julien, 2022, In: Acta Neuropathologica Communications. 10, 185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A Blunted GPR183/Oxysterol Axis during Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung during Mycobacterium tuberculosis Infection

    Ngo, M. D., Bartlett, S., Bielefeldt-Ohmann, H., Foo, C. X., Sinha, R., Arachchige, B. J., Reed, S., Mandrup-Poulsen, Thomas, Rosenkilde, Mette & Ronacher, K., 2022, In: Journal of Infectious Diseases. 225, 12, p. 2219-2228

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study

    Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 2022, In: Acta Dermato-Venereologica. 102, 5 p., adv00704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A Novel Dimeric Conotoxin, FrXXA, from the Vermivorous Cone Snail Conus fergusoni, of the Eastern Pacific, Inhibits Nicotinic Acetylcholine Receptors

    Rodriguez-Ruiz, X. C., Aguilar, M. B., Ortiz-Arellano, M. A., Safavi-Hemami, H. & Lopez-Vera, E., 2022, In: Toxins. 14, 8, 13 p., 510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A RANDOMIZED, CROSS-OVER STUDY TO INVESTIGATE THE EFFECT OF WEIGHT-BEARING VS NON-WEIGHT-BEARING EXERCISE AND CARDIOVASCULAR STRESS ON TYPE II COLLAGEN TURNOVER IN PATIENTS WITH KNEE OSTEOARTHRITIS - SERUM BIOMARKER DATA FROM THE EFEX-OA-02 STUDY

    Bjerre-Bastos, J. J., Sejersen, Casper Aastrup, Nielsen, H. B., Boesen, M., Secher, Niels H., Distajo, G., Flood, V., Henrotin, Y., Uebelhoer, M., Mackey, Abigail, Krustrup, P., Kitchen, C. -., Petersen, E. E., Thudium, C. S., Andersen, J. R. & Bihlet, A. R., 2022, In: Osteoarthritis and Cartilage. 30, p. S102-S103 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  15. Published

    A Scintillation Proximity Assay for Real-Time Kinetic Analysis of Chemokine-Chemokine Receptor Interactions

    Eberle, S. A. & Gustavsson, Martin, 2022, In: Cells. 11, 8, 15 p., 1317.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A VIRTUAL Sleep Apnoea management pathway For the work-up of Atrial fibrillation patients in a digital Remote Infrastructure: VIRTUAL-SAFARI

    Verhaert, D. V. M., Betz, K., Gawałko, M., Hermans, A. N. L., Pluymaekers, N. A. H. A., Van Der Velden, R. M. J., Philippens, S., Vorstermans, B., Simons, S. O., Den Uijl, D. W., Chaldoupi, S. M., Luermans, J. G. L. M., Westra, S. W., Lankveld, T., Kadhim, K., Pepin, J. L., Van Steenwijk, R. P., Hol, B., Schotten, U., Sanders, P. & 3 others, Vernooy, K., Hendriks, J. M. & Dr Linz, Dominik Karl, 2022, In: Europace. 24, 4, p. 565-575

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A Vasopressin-Induced Change in Prostaglandin Receptor Subtype Expression Explains the Differential Effect of PGE2 on AQP2 Expression

    Deen, P. M. T., Boone, M., Schweer, H., Olesen, Emma Tina Bisgaard, Carmone, C., Wetzels, J. F. M., Fenton, R. A. & Kortenoeven, M. L. A., 2022, In: Frontiers in Physiology. 12, 13 p., 787598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling

    Schreiber, J. A., Möller, M., Zaydman, M., Zhao, L., Beller, Z., Becker, S., Ritter, N., Hou, P., Shi, J., Silva, J., Wrobel, E., Strutz-Seebohm, N., Decher, N., Schmitt, Nicole, Meuth, S. G., Düfer, M., Wünsch, B., Cui, J. & Seebohm, G., 2022, In: Communications Biology . 5, 1, p. 1-13 301.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A convolutional neural network for total tumor segmentation in [64Cu]Cu-DOTATATE PET/CT of patients with neuroendocrine neoplasms

    Carlsen, E. A., Lindholm, Kristian, Hindsholm, A., Gæde, M., Ladefoged, C. N., Loft, M., Johnbeck, C. B., Langer, Seppo W., Oturai, P., Knigge, Ulrich, Kjær, Andreas & Andersen, Flemming Littrup, 2022, In: EJNMMI Research. 12, 1, p. 1-10 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients

    Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A guide to adhesion GPCR research

    Liebscher, I., Cevheroglu, O., Hsiao, C., Maia, A. F., Schihada, H., Scholz, N., Soave, M., Spiess, Katja, Trajkovic, K., Kosloff, M. & Proemel, S., 2022, In: FEBS Journal. 289, 24, p. 7610-7630

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A knowledge graph to interpret clinical proteomics data

    Santos, A., Colaço, A. R., Nielsen, A. B., Niu, Lili, Strauss, Maximilian, Geyer, P. E., Coscia, F., Albrechtsen, Nicolai Jacob Wewer, Mundt, F., Jensen, Lars Juhl & Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 692–702

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait

    Orozco, G. A., Karjalainen, K., Moo, E. K., Stenroth, Lauri, Tanska, P., Rios, J. L., Tuomainen, T. V., Nissi, M. J., Isaksson, H., Herzog, W. & Korhonen, R. K., 2022, In: PLOS Computational Biology. 18, 6, p. 1-23 e1009398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A new uPAR-targeting fluorescent probe for optical guided intracranial surgery in resection of a meningioma — a case report

    Skjøth, Jane, Azam, Aleena, Larsen, C. C., Scheie, David, Stræde, Karina & Kjær, Andreas, 2022, In: Acta Neurochirurgica. 164, 1, p. 267-271 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A randomised, factorial phase II study to determine the optimal dosing regimen for 68Ga-satoreotide trizoxetan as an imaging agent in patients with gastroenteropancreatic neuroendocrine tumours

    Virgolini, I., Bahri, S., Kjær, Andreas, Gronbaek, H., Iversen, P., Carlsen, E. A., Loft, M., Knigge, Ulrich, Maffey-Steffan, J., Powell, C., Miller, C. G., Rohban, T., McEwan, S. & Czernin, J., 2022, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A randomized double-blind single center study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Kreiberg, M., Jørgensen, N., Juul, Anders, Lauritsen, J., Oturai, P., Helge, Jørn Wulff, Christensen, J. F., Aksglaede, L., Schauer, T., Wagner, T., Rosenvilde, J., Grunwald, E., Dehlendorff, C., Daugaard, G. & Bandak, M., 2022, In: Clinical Genitourinary Cancer. 20, 5, p. 404-414 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A systematic review of mobile health opportunities for atrial fibrillation detection and management

    Hermans, A. N. L., Gawalko, M., Dohmen, L., Van Der Velden, R. M. J., Betz, K., Verhaert, D. V. M., Pluymaekers, N. A. H. A., Hendriks, J. M. & Dr Linz, Dominik Karl, 2022, In: European Journal of Preventive Cardiology. 29, 5, p. E205-E208

    Research output: Contribution to journalLetterResearchpeer-review

  30. Published

    Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists

    Stavnsbjerg, Camilla, Christensen, Esben, Münter, R., Henriksen, J. R., Fach, M., Parhamifar, L., Christensen, Camilla Hell, Kjær, Andreas, Hansen, A. E. & Andresen, T. L., 2022, In: Journal of Controlled Release. 342, p. 337-344

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Accuracy, analysis time, and reproducibility of dedicated 4D echocardiographic left atrial volume quantification software

    Olsen, F. J., Bertelsen, L., Vejlstrup, N., Bjerregaard, C. L., Diederichsen, S. Z., Jørgensen, P. G., Jensen, M. T., Dahl, A., Landler, N. E., Graff, C., Brandes, A., Krieger, D., Haugan, K., Køber, Lars Valeur, Højberg, S., Svendsen, Jesper Hastrup & Biering-Sørensen, Tor, 2022, In: International Journal of Cardiovascular Imaging. 38, p. 1277–1288

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Activity Dose Reduction in 64Cu-DOTATATE PET in Patients with Neuroendocrine Neoplasms: Impact on Image Quality and Lesion Detection Ability.

    Loft, M., Carlsen, Esben Andreas, Johnbeck, C. B., Jensen, C. V., Andersen, Flemming Littrup, Langer, Seppo W., Oturai, P., Knigge, Ulrich & Kjær, Andreas, 2022, In: Molecular Imaging and Biology. 24, p. 600–611

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published

    Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

    Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Acute normobaric hypoxia blunts contraction-mediated mTORC1- and JNK-signaling in human skeletal muscle

    Moberg, M., Apró, W., Horwath, O., van Hall, Gerrit, Blackwood, S. J. & Katz, A., 2022, In: Acta Physiologica. 234, 2, 19 p., e13771.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Adduction reactions of alpha,beta-unsaturated aldehydes to proteins

    Davies, Michael J., 2022, In: Toxicology Letters. 368, Suppl, p. S62-S62 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    Adrenaline autoinjector is underprescribed in typical cold urticaria patients

    Bizjak, M., Košnik, M., Dinevski, D., Thomsen, S. F., Fomina, D., Borzova, E., Kulthanan, K., Meshkova, R., Aarestrup, F. M., Ahsan, D. M., Al-Ahmad, M., Altrichter, S., Bauer, A., Brockstädt, M., Costa, C., Demir, S., Criado, R. F., Ensina, L. F., Gelincik, A., Giménez-Arnau, A. M. & 26 others, Gonçalo, M., Gotua, M., Holm, J. G., Inomata, N., Kasperska-Zajac, A., Khoshkhui, M., Klyucharova, A., Kocatürk, E., Lu, R., Makris, M., Maltseva, N., Pasali, M., Paulino, M., Pesqué, D., Peter, J., Ramón, G. D., Ritchie, C., Rodrigues Valle, S. O., Rudenko, M., Sikora, A., Wagner, N., Xepapadaki, P., Xue, X., Zhao, Z., Terhorst-Molawi, D. & Maurer, M., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 7, p. 2224-2229

    Research output: Contribution to journalLetterResearchpeer-review

  40. Published
  41. Published

    Age- and sex-based normal values of layer-specific longitudinal and circumferential strain by speckle tracking echocardiography: the Copenhagen City Heart Study

    Skaarup, K. G., Lassen, M. C. H., Johansen, N. D., Olsen, F. J., Lind, J. N., Jørgensen, P. G., Jensen, G., Schnohr, P., Prescott, Eva, Søgaard, P., Møgelvang, R. & Biering-Sørensen, Tor, 2022, In: European Heart Journal Cardiovascular Imaging. 23, 5, p. 629–640

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Age- and sex-specific effects of a long-term lifestyle intervention on body weight and cardiometabolic health markers in adults with prediabetes: results from the diabetes prevention study PREVIEW

    Zhu, R., Craciun, I., Bernhards-Werge, J., Jalo, E., Poppitt, S. D., Silvestre, M. P., Huttunen-Lenz, M., McNarry, M. A., Stratton, G., Handjiev, S., Handjieva-Darlenska, T., Navas-Carretero, S., Sundvall, J., Adam, T. C., Drummen, M., Simpson, E. J., Macdonald, I. A., Brand-Miller, J., Muirhead, R., Lam, T. & 5 others, Vestentoft, P. S., Færch, K., Martinez, J. A., Fogelholm, M. & Raben, Anne, 2022, In: Diabetologia. 65, 8, p. 1262-1277 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Aging is associated with an altered macrophage response during human skeletal muscle regeneration

    Ahmadi, M., Karlsen, Anders, Mehling, J., Soendenbroe, C., Mackey, Abigail & Hyldahl, R. D., 2022, In: Experimental Gerontology. 7 p., 111974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Amino Acid Metabolism and Protein Turnover in Lean and Obese Humans During Exercise-Effect of IL-6 Receptor Blockade

    Trinh, B., Peletier, M., Simonsen, C., Plomgaard, Peter Stendahl, Karstoft, Kristian, Pedersen, Bente Klarlund, van Hall, Gerrit & Ellingsgaard, H., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1854-1864

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Amiodarone attenuates cardiac Rubidium-82 in consecutive PET/CT scans in a rodent model

    Bentsen, Simon, Bang, L. E., Hasbak, P., Kjær, Andreas & Ripa, Rasmus Sejersten, 2022, In: Journal of Nuclear Cardiology. 29, p. 2853–2862

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journalComment/debateResearch

  47. Published

    An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity"

    Bodine, S. C., Brooks, H. L., Coller, H. A., Domingos, A. I., Frey, M. R., Goodman, B. E., Kleyman, T. R., Lindsey, M. L., Morty, R. E., Petersen, O. H., Ramírez, J. M., Schaefer, L., Thomsen, Morten Bækgaard & Yosten, G. L. C., 2022, In: American journal of physiology. Lung cellular and molecular physiology. 323, 5, p. L593-L602

    Research output: Contribution to journalEditorialResearchpeer-review

  48. Published

    An Estimate of Plasma Volume Changes Following Moderate-High Intensity Running and Cycling Exercise and Adrenaline Infusion

    Bjerre-Bastos, J. J., Sejersen, Casper Aastrup, Bihlet, A. R., Secher, Niels H., Mackey, Abigail, Kitchen, C., Drobinski, P., Thudium, C. S. & Nielsen, H. B., 2022, In: Frontiers in Physiology. 13, 8 p., 948097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    An MMP-degraded and cross-linked fragment of type III collagen as a non-invasive biomarker of hepatic fibrosis resolution

    Pehrsson, M., Manon-Jensen, T., Sun, S., Villesen, I. F., Castañé, H., Joven, J., Patel, K., Goodman, Z., Nielsen, M. J., Bay-Jensen, A. C., Leeming, D. J., Mortensen, J. H. & Karsdal, M. A., 2022, In: Liver International. 42, 7, p. 1605-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Grarup, N., Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.

    Research output: Contribution to journalConference abstract in journalResearch

  51. Published