Department of Biomedical Sciences

  1. 2023
  2. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mild-to-moderate severity of psoriasis may be assessed remotely based on photographs and self-reported extent of skin involvement

    Ali, Z., Robert Zibert, J., Dahiya, P., Bachdal Johansen, C., Grønlund Holm, J., Ravn Jørgensen, A. H., Manole, I., Suru, A., Egeberg, Alexander, Thomsen, Simon Francis & Andersen, A. D., 2023, In: JAAD International. 11, p. 129-136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

    Rusiecka, O. M., Molica, F., Nielsen, Morten Schak, Tollance, A., Morel, S., Frieden, M., Chanson, M., Boengler, K. & Kwak, B. R., 2023, In: Cardiovascular Research. 119, 13, p. 2342-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl) alters their reactivity with vascular smooth muscle cells.

    Hartsema, Els Alletta, Hallberg, L. A. E., Barlous, K. A. & Hawkins, Clare Louise, 2023, In: Redox Biochemistry and Biology. 5-6, 11 p., 100010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Molecular exploration of fossil eggshell uncovers hidden lineage of giant extinct bird

    Grealy, A., Miller, G. H., Phillips, M. J., Clarke, S. J., Fogel, M., Patalwala, D., Rigby, P., Hubbard, A., Demarchi, B., Collins, Matthew James, Mackie, Meaghan, Sakalauskaite, J., Stiller, Josefin, Clarke, J. A., Legendre, L. J., Douglass, K., Hansford, J., Haile, J. & Bunce, M., 2023, In: Nature Communications. 14, 14 p., 914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation

    Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, Per Mårten, Grune, T., Davies, Michael J., Bartesaghi, S. & Radi, R., 2023, In: Journal of Biological Chemistry. 299, 3, 22 p., 102941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Muscarinic acetylcholine receptors M2 are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block

    Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, T. H., Hesselkilde, E. M., Kjeldsen, S. T., Hopster-Iversen, Charlotte, D’Souza, A., Jespersen, Thomas & Buhl, Rikke, 2023, In: Frontiers in Cardiovascular Medicine. 10, 10 p., 1102164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival

    Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography

    Lassen, Martin Lyngby, Rasmussen, T., Byrne, C., Holmvang, Lene, Kjær, Andreas & Hasbak, P., 2023, In: Journal of Nuclear Cardiology. 30, 5, p. 2289-2300

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State

    Lewis, Christopher T.A. & Ochala, Julien, 2023, In: Physiology. 38, 1, p. 3-9

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations

    Sonne, A., Peverelli, L., Hernandez-Lain, A., Domínguez-González, C., Andersen, J. L., Milone, M., Beggs, A. H. & Ochala, Julien, 2023, In: American journal of physiology. Cell physiology. 324, 3, p. C769–C776 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle

    Henriquez-Olguín, Carlos, Meneses Valdés, Roberto Andrés, Raun, Steffen Henning, Gallero, S., Knudsen, Jonas Roland, Li, Z., Li, J., Sylow, Lykke, Jaimovich, E. & Jensen, Thomas Elbenhardt, 2023, In: Redox Biology. 65, 12 p., 102842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Nationwide Utilization of Danish Government Electronic letter system for increasing inFLUenza vaccine uptake (NUDGE-FLU): Study protocol for a nationwide randomized implementation trial

    Johansen, N. D., Vaduganathan, M., Bhatt, A. S., Lee, S. G., Modin, D., Claggett, B. L., Dueger, E. L., Samson, S., Loiacono, M. M., Køber, Lars Valeur, Solomon, S. D., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Valentiner-Branth, P., Krause, T. G. & Biering-Sørensen, Tor, 2023, In: American Heart Journal. 260, p. 58-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Neoadjuvant Gold Nanoshell-Based Photothermal Therapy Combined with Liposomal Doxorubicin in a Mouse Model of Colorectal Cancer

    Simón, M., Jørgensen, Jesper Tranekjær, Norregaard, K., Henriksen, J. R., Clergeaud, G., Andresen, T. L., Hansen, A. E. & Kjær, Andreas, 2023, In: International Journal of Nanomedicine. 18, p. 829-841

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers

    Jensen, M., Thorsen, N. W., Hallberg, L. A. E., Hägglund, Per Mårten & Hawkins, Clare Louise, 2023, In: Free Radical Biology and Medicine. 202, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Next-Level Natriuretic Peptide Measurement

    Nersting, J., Terzic, D., Hansen, L. H. & Goetze, Jens P. , 2023, In: Clinical Chemistry. 69, 4, p. 313-315 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  22. Published

    No diurnal variation is present in maximal fat oxidation during exercise in young healthy women: A cross-over study

    Robles-González, L., Aguilar-Navarro, M., López-Samanes, Á., Ruiz-Moreno, C., Muñoz, A., Varillas-Delgado, D., Gutiérrez-Hellín, J., Helge, Jørn Wulff, Ruiz, J. R. & Amaro-Gahete, F. J., 2023, In: European Journal of Sport Science. 23, 6, p. 936–942

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events

    Shahrbabaki, S. S., Dr Linz, Dominik Karl & Baumert, M., 2023, In: International Journal of Cardiology. 385, p. 55-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Non-invasive methods to assess muscle function in dogs: A scoping review

    Dahl, Kathrine Højte, Zebis, Mette Kreutzfeldt, Vitger, Anne Désiré, Miles, James Edward & Alkjær, Tine, 2023, In: Frontiers in Veterinary Science. 10, p. 1-10 1116854.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Normal Values and Reference Ranges for the Ratio of Transmitral Early Filling Velocity to Early Diastolic Strain Rate: The Copenhagen City Heart Study

    Lassen, M. C. H., Skaarup, K. G., Johansen, N. D., Olsen, F. J., Qasim, A. N., Jensen, G. B., Schnohr, P., Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Journal of the American Society of Echocardiography. 30, 11, p. 1204-1212

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology

    Mia, S., Sonkar, R., Williams, L., Latimer, M. N., Rawnsley, D. R., Rana, S., He, J., Dierickx, P., Kim, T., Xie, M., Habegger, K. M., Kubo, M., Zhou, L., Thomsen, Morten Bækgaard, Prabhu, S. D., Frank, S. J., Brookes, P. S., Lazar, M. A., Diwan, A. & Young, M. E., 2023, In: JACC: Basic to Translational Science. 8, 9, p. 1141-1156 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Nutritional treatment of atopic diseases according to YouTube videos

    Høj, S., Meteran, H., Thomsen, Simon Francis, Sigsgaard, T. & Meteran, Howraman, 2023, In: Journal of Allergy and Clinical Immunology: In Practice. 11, 5, p. 1552-1553

    Research output: Contribution to journalComment/debateResearchpeer-review

  29. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    Obesity is transferable through the gut microbiota

    Choi, Beatrice So-Yun & Jensen, Sune K. , 2023, In: Nature Reviews Endocrinology. 19, p. 687

    Research output: Contribution to journalComment/debateResearch

  31. Published

    Obesity-induced changes in gene expression in feline adipose and skeletal muscle tissue

    Jensen, Kathrine Stenberg, Novotny, G. W., Lutz, T. A., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2023, In: Journal of Animal Physiology and Animal Nutrition. 107, 5, p. 1262 - 1278

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Occurrence and risk factors of mental disorders in patients with chronic urticaria

    Ghazanfar, M. N., Sørensen, J. A., Zhang, D., Holgersen, N. K., Vestergaard, C. & Thomsen, Simon Francis, 2023, In: World Allergy Organization Journal. 16, 11, 4 p., 100835.

    Research output: Contribution to journalLetterResearchpeer-review

  33. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Organism-wide, cell-type-specific secretome mapping of exercise training in mice

    Wei, W., Riley, N. M., Lyu, X., Shen, X., Guo, J., Raun, Steffen Henning, Zhao, M., Moya-Garzon, M. D., Basu, H., Sheng-Hwa Tung, A., Li, V. L., Huang, W., Wiggenhorn, A. L., Svensson, K. J., Snyder, M. P., Bertozzi, C. R. & Long, J. Z., 2023, In: Cell Metabolism. 35, 7, p. 1261-1279 19 p., e11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram

    Maurya, S., Mills, Robert William, Kahnert, Konstantin, Chiang, D. Y., Bertoli, G., Lundegaard, Pia Rengtved, Duran, M. P. H., Zhang, M., Rothenberg, E., George, A. L., MacRae, C. A., Delmar, M. & Lundby, Alicia, 2023, In: Nature Cardiovascular Research. 2, 7, p. 673-692 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells

    Clemen, R., Fuentes Lemus, Eduardo, Bekeschus, S. & Davies, Michael J., 2023, In: Redox Biology. 65, 14 p., 102835.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes

    Popa, I., Touboul, D., Andersson, T., Fuentes Lemus, Eduardo, Santerre, C., Davies, Michael J. & Lood, R., 2023, In: Microorganisms. 11, 9, 15 p., 2260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    PCM1 labeling reveals myonuclear and nuclear dynamics in skeletal muscle across species

    Viggars, M. R., Owens, D. J., Stewart, C., Coirault, C., Mackey, Abigail & Jarvis, J. C., 2023, In: American Journal of Physiology: Cell Physiology. 324, 1, p. C85-C97

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    PaCO2 trajectories in mechanically ventilated patients with COVID-19: A population-based cohort study

    Berg, R. M. G., Ronit, A., Haase, N., Moller, M. H., Kristiansen, K. T. T., Jonassen, T., Wamberg, C., Andreasen, A. S., Mohr, T., Bestle, M. H. H., Jorgensen, V. L. L., Hammer, N. R. R., Mitchell, A. U. U., Smitt, M., Greve, A. M., Nyeland, M. E., Jensen, B. W., Andreasen, A. H., Petersen, J., Solem, E. J. & 2 others, Winther-Jensen, M. & Plovsing, R. R. R., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 779-787 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Parameters associated with improvement of systolic function in patients with heart failure

    Schöps, L. B., Sengeløv, M., Modin, D., Jørgensen, P. G., Bruun, Niels Eske, Fritz-Hansen, T., Gislason, Gunnar Hilmar, Wolsk, E., Schou, M. & Biering-Sørensen, Tor, 2023, In: Heart. 110, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Pathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?

    Harris, K. M., Arya, R., Elias, A., Weber, T., Green, D. A., Greaves, D. K., Petersen, L. G., Roberts, L., Kamine, T. H., Mazzolai, L., Bergauer, A., Kim, D. S., Olde Engberink, R. H., zu Eulenberg, P., Grassi, B., Zuccarelli, L., Baldassarre, G., Tabury, K., Baatout, S., Jordan, J. & 4 others, Blaber, A. P., Choukér, A., Russomano, T. & Goswami, N., 2023, In: npj Microgravity. 9, 1, 7 p., 17.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Patient motivation and adherence to an on-demand app-based heart rate and rhythm monitoring for atrial fibrillation management: data from the TeleCheck-AF project

    TeleCheck-AF investigators, T. I., 2023, In: European Journal of Cardiovascular Nursing. 22, 4, p. 412–424

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

    Mavri, M., Glišić, S., Senćanski, M., Vrecl, M., Rosenkilde, Mette, Spiess, Katja & Kubale, V., 2023, In: Cellular and Molecular Biology Letters. 28, 1, 19 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Peptidylglycine α-amidating monooxygenase and adrenomedullin measurement in patients with hepatic cirrhosis

    Goetze, Jens P. , Voiosu, A., Wiese, S., Schulte, J., Kaufmann, P., Bergmann, A., Bartels, Emil Daniel & Møller, Søren, 2023, In: Biomarkers in Medicine. 17, 13, p. 577-583 7 p.

    Research output: Contribution to journalLetterResearchpeer-review

  47. Published

    Performance of 8- vs 16 ECG-gated reconstructions in assessing myocardial function using Rubidium-82 myocardial perfusion imaging: Findings in a young, healthy population

    Lassen, Martin Lyngby, Wissenberg, M., Byrne, C., Kjær, Andreas & Hasbak, P., 2023, In: Journal of Nuclear Cardiology. 30, 4, p. 1406-1413

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Performance of Panel-Estimated GFR Among Hospitalized Older Adults

    Iversen, E., Bengaard, A. K., Leegaard Andersen, A., Tavenier, J., Nielsen, R. L., Juul-Larsen, H. G., Jørgensen, L. M., Bornæs, O., Jawad, B. N., Aharaz, A., Walls, Anne Byriel, Kallemose, T., Dalhoff, Kim, Nehlin, J. O., Hornum, Mads, Feldt-Rasmussen, Bo, Damgaard, Morten, Andersen, Ove & Houlind, Morten Baltzer, 2023, In: American Journal of Kidney Diseases. 82, 6, p. 715-724 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Peripheral blood mononuclear cells exhibit increased mitochondrial respiration after adjuvant chemo- and radiotherapy for early breast cancer

    Christensen, I. B., Abrahamsen, Marie-Louise Brødsgaard, Ribas, L., Buch-Larsen, K., Marina, D., Andersson, M., Larsen, Steen, Schwarz, Peter, Dela, Flemming & Gillberg, Linn, 2023, In: Cancer Medicine. 12, 16, p. 16985-16996 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Peroxyl radicals modify 6-phosphogluconolactonase from Escherichia coli via oxidation of specific amino acids and aggregation which inhibits enzyme activity

    Reyes, J. S., Fuentes Lemus, Eduardo, Romero, J., Arenas, F., Fierro, A., Davies, Michael J. & López-Alarcón, C., 2023, In: Free Radical Biology and Medicine. 204, p. 118-127

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events

    Linz, Benedikt Maximilian, Hesselkilde, E. M., Skarsfeldt, M. A., Hertel, Julie Norup, Sattler, Stefan M, Yan, Y., Tfelt-Hansen, Jacob, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Dr Linz, Dominik Karl & Jespersen, Thomas, 2023, In: Journal of Cardiovascular Electrophysiology. 34, 1, p. 126-134 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review